Because of its anatomical/physiological characteristics, the Class II division 2 (class II, div. 2) is one of the malocclusions considered as a possible risk factor for Temporomandibular disorders (TMD). A literature review was conducted from the electronic databases of Medline and Elsevier Masson, through the year 2010, in order to clarify the relationships that may exist between Class II division 2 and TMD. This research helped identify 50 articles: 7 articles specifically concerned the Class II div. 2, 37 articles concerned some of the characteristics of the Class II div. 2, considered individually (Class II, deep bite, retroclined maxillary incisors, mandibular retrognathism) and 6 articles orthodontic treatment. From the conclusions of these studies, the Class II, div. 2 does not appear to represent a significant risk factor for TMD. The clearest association would involve mandibular retrognathism and the risk of articular disk displacement. However, given the low number of articles published on this topic, the methodological variability and the contradictory results, it is difficult to identify reliable conclusions and, consequently, the therapeutic indications for the treatment of Class II div. 2 patients with TMD.
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