2014 Internal medicine journal

Use of infliximab and other biologics in Behcet disease.

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Internal medicine journal Vol. 44 (1) : 96-100 • Jan 2014

Behcet disease is a multisystem vasculitis characterised by recurrent oral ulceration in conjunction with other manifestations. Neurological involvement or neuro-Behcet disease is not common, but typically affects young men at its onset between the ages of 20 and 40 with significant long-term morbidity and mortality. There is substantial case literature to support the use of tumour necrosis factor antagonists, notably infliximab, in the treatment of neuro-Behcet disease.

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