Investigation of treatment options to minimize the effects of acid erosion on enamel.

This in vitro study investigated 4 products (containing calcium, phosphate, and/or fluoride) and their ability to reharden enamel softened by hydrochloric acid as compared to hardening with saliva alone. Extracted human molars were embedded and polished, and baseline Vickers hardness (VH) of enamel was measured. Statistical analysis was performed with ANOVA followed by Student-Newman-Keuls post hoc tests (P = 0.05). For all groups, VH decreased significantly after immersion in hydrochloric acid. Fluoride in combination with casein phosphopeptide amorphous calcium phosphate was the most effective treatment for enamel hardness recovery.