PURPOSE: To investigate the effect of resin cement color on the post-cementation shade of thin laminate veneers milled from multilayered glass ceramic blocks for each layer. MATERIALS AND METHODS: Thin slices (N = 180) with two thicknesses (A: 8 x 8x0.55 mm and B: 8x8x0.8 mm; n = 90/group) were obtained from multilayered glass ceramic blocks using a diamond saw. Resin die specimens were prepared (8 x 8 x 4 mm) (n = 180) and divided into two resin cement colors (D: -3. L: +3) and one control group (C: translucent). Each slice was luted to the composite specimens using a dual-curing resin cement under a constant load of 250 g and light-polymerized for 120 seconds. Specimens were placed on a white background and CIELab values for each layer of the blank slices (incisal [In], body [Bo], and cervical [Ce]) were recorded using a dental contact spectrophotometer. The values were calculated as DeltaE, and the data were statistically analyzed (one-way ANOVA, Shapiro-Wilk). RESULTS: Mean DeltaE values for A and B were significant (p < 0.05) for In (A: 6.2 +/- 1.1; B: 6.6 +/- 1.2), Bo (A: 5.1 +/- 2.6; B: 3.9 +/- 1), and Ce (A: 5.3 +/- 2.7; B: 3.8 +/- 1.2). Mean DeltaE values for In for D and L for A and B groups were significantly higher (6.3 +/- 1.2; 6.6 +/- 1.2) than Bo and Ce for D (4.4 +/- 2.4; 4.6 +/- 2.6) and L (4.6 +/- 1.4; 4.5 +/- 1.7) groups (p < 0.05), respectively. Mean differences between Bo and Ce for A and B groups were insignificant (p >/= 0.05), while for In the differences were significant. Mean differences between Bo and Ce for A (5.1 +/- 2.6; 5.3 +/- 2.7) and for B (3.9 +/- 1; 3.5 +/- 1.2) groups were insignificant (p >/= 0.05), while for In the differences were significant (6.2 +/- 1.1 for A and 6.6 +/- 1.2 for B). CONCLUSION: The color changes for body and cervical regions of multilayered ceramic veneers were not affected by resin color or ceramic thickness, but the incisal area was affected. The translucency of each layer in ceramic veneer fabricated with multilayered blanks should be considered for clinical situations.
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