OBJECTIVE: The aim of this study was to investigate the connection between preradiotherapy dental extractions and self-reported health-related QoL. STUDY DESIGN: Retrospective data on patients treated with radiotherapy for oropharyngeal cancer were pooled with the results of a cross-sectional survey. RESULTS: Greater than eight preradiotherapy dental extractions, p16 negative status, female gender, and positive smoking status were associated with statistically significant reduced QoL. CONCLUSIONS: Preradiotherapy dental extractions do not result in improved QoL and, in fact, may worsen it.
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