Allergen-triggered lichenoid oral mucosa lesions may occur both in oral lichen planus (OLP) and oral lichenoid lesions (OLL). Clinically, OLP and OLL are difficult to distinguish from each other. An OLP should be checked by histological examination. Therefore all patients with OLP should be included into a close control interval due to the the potential malignant transformation, whereas in the literature a higher risk of malignancy is attributed to OLL in comparison with OLP. Based on a clinical case, it is demonstrated that an interdisciplinary approach in allergy and mucous diagnosis is necessary to verify the correaltion between a contact allergy to amalgam and the lichenoid mucosal lesions. The subsequent treatment exemplifies the steps of dental therapies with multiple contact allergies to dental materials.
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