Sharply defined radiolucencies on a panoramic radiograph are often interpreted as cystic laesions. In some cases, however, it appears to be another condition, or an anatomical variation. In the present case, involving 2 healthy patients, 1 or more sharply defined lucencies were seen in the lateral parts of the mandible. After exploration, in both cases, an empty cavity was found without epithelial lining, which is pathognomonic for a simple bone cyst. Multiple occurrences are uncommon.
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