Myeloid sarcomas of the oral cavity are exceedingly rare. This report describes a recent case, and reviews the literature. This case report serves three purposes: 1) to demonstrate that the use of an intraoral biopsy can diagnose severe systemic disease; 2) to remind practitioners to be cognizant of less common diagnoses in the differential diagnosis of facial swelling; and 3) to contribute a case of myeloid sarcoma that was confirmed by flow cytometry to the published data.
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