INTRODUCTION: The purpose of this study was to determine the prevalence and size of periapical radiolucencies using cone-beam computed tomographic (CBCT) imaging in teeth without apparent signs of intraoral radiographic lesions. METHODS: One hundred twenty roots from 53 patients who had been determined to have no signs of intraoral radiographic lesions were included in this study. Limited-volume CBCT scans were taken at 0.125-mm(3) voxel size. The widest area of apical radiolucency of each root canal-treated tooth was measured and assigned a numeric score based on the CBCT-Endodontic Radiolucency Index (ERI). CBCT data were evaluated by 2 radiologists with an interclass correlation coefficient of 0.96. RESULTS: The majority of roots (53.3%) had periodontal ligament widths </=0.5 mm; 26.7% had radiolucency widths of 0.5 < x </= 1 mm, 15.0% had radiolucency widths of 1.0 < x </= 1.5 mm, 0.8% had radiolucency widths of 1.5 < x </= 2.0 mm, 1.7% had radiolucency widths of 2.0 < x </= 2.5 mm, and 2.5% had radiolucency widths of >2.5 mm. Patient age, recall interval, tooth type, and arch type had no statistically significant effect on the ERI distribution. CONCLUSIONS: Twenty percent of teeth with successful root canal treatment based on conventional periapical imaging had CBCT radiolucencies measuring greater than 1 mm. Because these radiolucencies may not be pathological changes, clinicians are cautioned against overtreatment of them before determining the true nature of these findings. Clinical studies with long follow-up times are needed to determine the proper course of actions for these cases.
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