2019 Gan to kagaku ryoho. Cancer &…

[A Case of Intracranial Epidural Abscess Secondary to Medication-Related Osteonecrosis of the Jaw].

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Gan to kagaku ryoho. Cancer & chemotherapy Vol. 46 (2) : 271-273 • Feb 2019

Recently, bisphosphonate and denosumab have been widely used for the treatment of bone metastasis of breast cancer. However, medication-related osteonecrosis of the jaw(MRONJ)has often been reported as a side effect of these drugs. We experienced a rare case of intracranial epidural abscess secondary to MRONJ. The patient died of the condition, although chemotherapy was effective. The mechanism of and therapy for MRONJ have not been clarified; therefore, its prevention should be emphasized.

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