Phineas T. Barnum (1810-1891) and Gardner Q. Colton (1814-1898) both entered the laughing gas show business in Manhattan in 1844. With Horace Wells (1815-1848), Colton introduced inhaled nitrous oxide for dental anesthesia in December 1844. The Barnumesque nature of laughing gas exhibitions may have contributed to the initially negative reception of nitrous anesthesia as humbug. Colton continued laughing gas shows after 1844, and he performed in a Barnum forum in Boston in 1862. In 1863, Barnum encouraged Colton to establish a flourishing painless dentistry practice in Manhattan. Barnum designated himself to be the Prince of Humbug. He embraced humbug for entertainment purposes but decried medical humbug. Notwithstanding, Barnum explicitly evinced awareness of the power of the placebo response. Accordingly, the proneness of individuals to deem impersonal all-purpose assessments to be personally applicable is dubbed the Barnum effect. Barnum was indirectly connected to Painless Parker (1872-1952), a dentist who exploited sensational advertising and humbug and ran a circus.
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