Assessment of sphenoid sinus types in patients with cleft lip and palate on cone-beam CT.

PURPOSE: The aim of this study is to examine the sphenoid sinus morphology and variations in patients with cleft lip and palate (CLP) on cone-beam computed tomography (CBCT) images, and to compare them with healthy controls. METHODS: CBCT images of 54 patients (28 males and 26 females,) with CLP and 54 age- and gender-matched healthy individuals (28 males and 26 females) were retrospectively evaluated. Sphenoid sinus main types (conchal, presellar, sellar, postsellar), sellar subtypes, clival and lateral extensions, and sinus septation were analyzed in CLP and control groups. The data were statistically analyzed using Chi-square test to compare the groups. RESULTS: A statistically significant difference was found between CLP and control groups for sphenoid sinus main types (p < 0.05). Presellar type was more commonly observed in CLP group (18.5%), while the postsellar (31.5%) and clival (17.7%) types were more frequent in control group. There was a significant difference between the groups among different sellar sinus subtypes (p < 0.05). A significant difference was detected between the groups for clival extensions of sphenoid sinus (p < 0.05), but no difference was found for the lateral extensions (p > 0.05). No significant difference was determined between groups for sphenoid sinus septation (p > 0.05). CONCLUSION: Significant differences were found between the CLP and control groups in terms of sphenoid sinus main types, sellar subtypes and the clival extensions. Knowledge of sphenoid sinus pneumatization in patients with CLP is important for preventing complications during transsphenoidal surgery.