OBJECTIVE: To assess the degree of influence of human blood plasma simulating dentinal fluid on the composite resin adhesion to dental hard tissues. MATERIAL AND METHODS: The strength of the adhesive bond between the composite material and dental hard tissues was studied using a shear test machine Zwick Roell Z 010 (<<Zwick>>, Germany) on extracted human teeth. XP Bond one-component adhesive system and XENOV self-etching adhesive system (DENTSPLY, Germany), high-definition micrometric restoration material Esthet X HD (DENTSPLY, Germany), as well as centrifuged blood plasma were used. RESULTS: Adhesion strength decreased by 26-78% when blood plasma weighing from 0.2 to 2.0 mg mixed up the self-etching system (weight 6.6 mg). A significant decrease in the adhesion force occurred when plasma with a mass of 0.7 mg or more mixed up with the monomer (a decrease in adhesion by 19.1%). A critical decrease in the adhesion force (43% or more) occurred with the mixture of blood plasma weighing 2.0 mg or more.
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