Functional Appliances May Be Effective in Correcting Skeletal Class II Malocclusion in the Long Term; However, the Quality of the Evidence Was Very Low and the Clinical Significance Was Limited.

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Long-term effects of functional appliances in treated versus untreated patients with class II malocclusion: A systematic review and meta-analysis. Cacciatore G, Ugolini A, Sforza C, Gbinigle O, Pluddemann A. PLoS One 14:e0221624. SOURCE OF FUNDING: Authors reported no specific funding for this research study. TYPE OF STUDY/DESIGN: Systematic review with meta-analysis of data.