2020 Journal of anesthesia history

From ACE to ACENO: How America's Munson added Harley's British mixture to nitrous oxide.

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Journal of anesthesia history Vol. 6 (3) : 168-169 • Sep 2020

An Ohio dentist, Corydon Munson, patented a gasometer with an attachment for vaporizing trace amounts of volatile general anesthetics or their mixtures into unoxygenated nitrous oxide. After vaporizing a variant of George Harley's ACE mixture into nitrous oxide, Munson branded his own novel anesthetic combination as ACENO.

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