2021 Brain and nerve = Shinkei ken…

[Sjogren's Syndrome].

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Brain and nerve = Shinkei kenkyu no shinpo Vol. 73 (5) : 552-559 • May 2021

Sjogren's syndrome is an autoimmune disease characterized by chronic sialadenitis and keratoconjunctivitis sicca. While dryness of the salivary and lacrimal glands is a core symptom, neurological complications are known to occur as part of a variety of extraglandular manifestations. The reported frequency of neurological complications ranges from 1.8% to 60%, with a wide variety of central, peripheral, and muscular manifestations. In 25% of cases, neurological symptoms precede the diagnosis of Sjogren's syndrome. Therefore, in the presence of unexplained neurological symptoms, it is important to exclude Sjogren's syndrome.

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