AIM: To present the 5 years outcomes of a reconstructive surgical protocol for peri-implantitis defects with different morphologies, by means of deproteinized bovine bone mineral with 10% collagen (DBBMC). MATERIAL AND METHODS: The original population of this case series consisted of 75 patients with one crater-like defect and probing depth (PD) >/=6 mm. After flap elevation, defects were assigned to one characteristic class and treated by means of DBBMC. Following healing, patients were enrolled in an individualized supportive periodontal/peri-implant (SPT) program. RESULTS: Fifty-one patients reached the 5 years examination, as 11 patients were lost to follow-up and 13 implants were removed. Overall treatment success was registered in 29 patients (45.3%). Mean PD and BOP significantly decreased at one year and remained stable for the rest of observation period. No correlation was found between implant survival rate and defect configuration (p = 0.213). Patients, who did not fully adhere to the SPT, experienced more complications and implant loss than those who regularly attended recall appointments (p = 0.009). CONCLUSIONS: The proposed reconstructive treatment resulted in a high 5 years implant survival rate in patients who fully adhered to SPT. The resolution of the peri-implantitis defect does not seem significantly associated with the defect configuration at the time of treatment.
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