BACKGROUND: Self-tapping screws have been extensively used for dental implants. Their biomechanical behavior is highly associated with their clinical success, particularly for screws used for immediate implant placement and restoration, because occlusal forces can directly affect the loading transfer at the bone-implant interface after implantation. The effect of implant design on the initial stability of self-tapping screws remains unclear. This study explored the biomechanical behaviors of implant stability in standardized implants with different design features. METHODS: Six types of dental implants were designed using computer-aided design/computer-aided manufacturing technology, including three types of cutting flute shapes (spiral, straight, and non-self-tapping) combined with two types of screw features. Peak insertion torque values were first recorded; initial stability levels were subsequently evaluated in terms of the maximum force and resistance to lateral loads using an electrodynamic test system. FINDINGS: The peak insertion torque values, maximum force, and resistance to lateral loads of the non-self-tapping groups were higher than those of the self-tapping groups by 17%-90% (p < 0.01). The peak insertion torque values of the Straumann implant with a spiral flute was higher than that of the original straight flute by 20% (p < 0.001). However, compared with the original spiral flute, the Nobel Biocare implant with straight flute had a 23% higher maximum force (p = 0.016) and 24.5% higher resistance (p = 0.012) under lateral loading. INTERPRETATION: Changing the flute design would affect initial implant stability. Non-self-tapping implants exhibited superior initial stability than did self-tapping implants.
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