BACKGROUND: The aim of the study was to test caries preventive gel compositions by a developed and patented objective laboratory method for evaluating the effectiveness of prophylactic agents based on the active transport of ions through tooth enamel. MATERIAL AND METHODS: The experiment used a prototype device for assessing ion transport and pork fangs filled with saline solution and immersed in various caries preventive media. An electric current was passed through the device and then the internal solution was analyzed in laboratory conditions for the concentration of ions in it. RESULTS: Minimal fluoride concentration (F</=500 ppm) with optimal concentration of calcium and phosphate ions does not impair ion transport to deep layers of enamel thus promoting active remineralization of dental hard tissues. CONCLUSION: During the experiment, the most active and promising gel-based caries preventive compositions were established, and a method for evaluating the effectiveness of prophylactic agents was proposed.
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