OBJECTIVES: The influence of different cleaning methods, air-abrasion parameters, and aging on shear bond strength (SBS) and tensile bond strength (TBS) of 3D resin luted to composite resin. MATERIALS AND METHODS: Nine hundred resin substrates were 3D printed (D20II, Rapid Shape) and cleaned with either isopropanol (ISO), butyldiglycol-based solution (BUT), or centrifugation (CEN). After 24-h storage in 37 degrees C water, specimens were air-abraded (mean particle size 50 microm; n = 60) with either alumina at 0.1 MPa (AL0.1) or 0.4 MPa (AL0.4) and glass pearls at 0.1 MPa (GP0.1) and 0.4 MPa (GP0.4) or conditioned with visio.link (control) and luted with PanaviaV5. Initially (24 h, 37 degrees C water storage) or after aging (10,000 thermal cycles), SBS and TBS were measured, and fracture types were examined. Surface free energy (SFE) and roughness (Ra) were determined after air-abrasion. Kolmogorov-Smirnov, Kruskal-Wallis H, Mann-Whitney U, chi-square, and partial eta-squared were computed. RESULTS: SBS measurements presented higher values than TBS (p < 0.001-0.033). Within the pretreatment groups, CEN showed the highest SBS and TBS values compared to cleaning with ISO or BUT (p < 0.001-0.040). Pretreatment with GP0.1 displayed the lowest bond strength values (p < 0.001-0.049), and mostly adhesive fractures occurred. The highest Ra values (p < 0.001) were observed for AL0.4 pretreatment. CONCLUSIONS: Pretreatment with AL0.4 and the control group mainly presented the highest bond strength values. Thermocycling had a positive effect on the bond strength. CLINICAL RELEVANCE: According to this study, 3D-printed restorations should be pretreated with AL0.4 or with visio.link before adhesive luting, regardless of their cleaning.
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