BACKGROUND: The study evaluates the position and displacement tendency of unerupted maxillary canines in orthodontic patients with non-syndromic craniofacial disorders (CD) compared to a control (C) group. METHODS: Canine position and displacement tendency were evaluated using panoramic radiographs (PAN) examined with parameters such as sector classification (sectors 1-5) and inclination angles (alpha and beta). The displacement tendency was defined as the positioning of the tip in sectors 1 or 2, as well as its combination with increased angles (alpha > 30 degrees and beta > 39 degrees ). In addition, the correlation of the tooth position and agenesis, cleft side, and sex was assessed. RESULTS: A total of 116 pre-treatment PAN, divided into the CD group (n = 50; mean age 8.32 +/- 2.27 years) and the C group (n = 66; mean age 10.80 +/- 2.82 years), were evaluated in this study. The sector classification showed no displacement tendency in both groups. Inclination angles alpha/beta showed a statistically significant higher displacement tendency (p = 0.01) of the CD group (n = 5) on the right side, compared to healthy subjects (n = 1). Male CD patients had a statistically significant higher displacement tendency on the right side (p = 0.03). A statistically significant correlation between cleft and non-cleft-side (p = 0.03) was found. CONCLUSION: Patients with CD showed a statistically significant higher displacement tendency of the maxillary canine affected by the cleft side. The inclination angle was found to be the better predictor compared to the sector classification which should be considered in the orthodontic treatment planning.
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