Smartphone-generated 3D facial images: reliable for routine assessment of the oronasal region of patients with cleft or mere convenience? A validation study.

OBJECTIVES: To evaluate the validity and reliability of smartphone-generated three-dimensional (3D) facial images for routine evaluation of the oronasal region of patients with cleft by comparing their accuracy to that of direct anthropometry (DA) and 3dMD. MATERIALS AND METHODS: Eighteen soft-tissue facial landmarks were manually labelled on each of the 17 (9 males and 8 females; mean age 23.3 +/- 5.4 years) cleft lip and palate (CLP) patients' faces. Two surface imaging systems, 3dMDface and Bellus3D FaceApp, were used to perform two imaging operations on each labelled face. Subsequently, 32 inter-landmark facial measurements were directly measured on the labelled faces and digitally measured on the 3D facial images. Statistical comparisons were made between smartphone-generated 3D facial images (SGI), DA, and 3dMD measurements. RESULTS: The SGI measurements were slightly higher than those from DA and 3dMD, but the mean differences between inter-landmark measurements were not statistically significant across all three methods. In terms of clinical acceptability, 16% and 59% of measures showed differences of </= 3 mm or </= 5 masculine, with good agreement between DA and SGI and 3dMD and SGI, respectively. A small systematic bias of +/- 0.2 mm was observed generally among the three methods. Additionally, the mean absolute difference between the DA and SGI methods was the highest for linear measurements (1.31 +/- 0.34 mm) and angular measurements (4.11 +/- 0.76 masculine). CONCLUSIONS: SGI displayed fair trueness compared to DA and 3dMD. It exhibited high accuracy in the orolabial area and specific central and flat areas within the oronasal region. Notwithstanding this, it has limited clinical applicability for assessing the entire oronasal region of patients with CLP. From a clinical application perspective, SGI should accurately encompass the entire oronasal region for optimal clinical use. CLINICAL RELEVANCE: SGI can be considered for macroscopic oronasal analysis or for patient education where accuracy within 3 mm and 5 masculine may not be critical.