2025 Seminars in diagnostic pathol…

Exploring the debates surrounding keratoameloblastoma: An in-depth review of an emerging entity.

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Seminars in diagnostic pathology Vol. 42 (1) : 37-43 • Jan 2025

Ameloblastoma is a benign odontogenic epithelial tumor characterized by its aggressive behavior and a high likelihood of local recurrence if not fully excised. Ameloblastomas are a common type of slow-growing, true jaw tumor which may present as solid, multicystic or unicystic forms and originate from odontogenic epithelium and exhibit a variety of histological patterns. Keratoameloblastoma is considered to be a rare variant of ameloblastoma associated with more intense keratinization. Therefore, in this present review, authors report a case of keratoameloblastoma in a 14-year-old male and review giving a sneak-peek into this lesion with insight into the literature concerning its presentation, incidence, aetiology, clinical features, radiological appearance, histopathological findings and treatment options along with the current literature about this lesion.

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