2025 BMJ case reports

Late-onset distant metastasis in parotid gland myoepithelial carcinoma.

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BMJ case reports Vol. 18 (1) • Jan 2025

Myoepithelial carcinoma (MC) is a rare salivary gland malignancy that usually affects people over the age of 50. The incidence is similar in both men and women. MC might develop de novo or within a pre-existing benign myoepithelioma or pleomorphic adenoma. Reports on MC clinical behaviour differ. Here, we present the case of a female patient in her 60s who had surgery for parotid gland MC. Seven years after parotidectomy, a distant metastasis was found in the sixth left rib, and she underwent a metastasectomy. Nine years after the initial surgery, another distant metastasis was detected in the fifth right rib, and a second metastasectomy was performed. Throughout this period, there was no locoregional recurrence of the disease. This case highlights the need for continued research on the clinical behaviour of salivary glands MC and the importance of regular and long follow-up and monitoring for distant metastases.

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