Behcet's disease, also known as the oral-ocular-genital syndrome, is a chronic systemic vasculitis characterized by recurrent oral and genital ulcers as well as ocular manifestations such as uveitis and conjunctivitis. When the cardiovascular system is predominantly affected, the condition is known as cardiac Behcet's disease. This variant can manifest as aortic valve regurgitation, conduction system disorders, myocarditis, and even acute myocardial infarction. Aortic regurgitation is an exceedingly rare and threatening cardiovascular complication in patients with Behcet's disease, often indicating a poor prognosis. Surgical intervention for aortic regurgitation in patients with Behcet's disease is associated with high risks of postoperative complications and mortality. To mitigate these risks, techniques such as the Bentall procedure have been employed. This report describes the case of a patient with Behcet's disease and severe aortic regurgitation who underwent the Bentall procedure. Unfortunately, the patient developed a pseudoaneurysm and prosthetic valve detachment at the aortic root 3 months postoperatively. This severe complication necessitated a subsequent intervention utilizing the Cabrol technique for correction.
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