2025 Journal of endodontics

Clinician Perspective of Regenerative Endodontic Procedures for Immature Anterior Teeth: An Observational Web-based Study.

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Journal of endodontics Vol. 51 (8) : 1061-1071 • Aug 2025

INTRODUCTION: Regenerative endodontic procedures (REPs) are beneficial in preserving infected immature permanent teeth. The aim of this observational study was to assess treatment planning of REPs, geographical differences in their provision, clinical hesitancy and provision rate. METHODS: Digitally manipulated radiographs showing varying degrees of root development in a maxillary central incisor with apical pathosis were used in an anonymized online questionnaire to assess clinical predisposition. The data were analyzed using descriptive statistics. RESULTS: Among 160 participants (59.4% specialist endodontists), 73.1% favored REPs for the most immature apices, decreasing with root maturity. Specialist experience did not impact REP provision. UK endodontists performed REPs less frequently than international counterparts. Key perceived REP benefits included fracture resistance and root lengthening. Hesitancy stemmed from unfamiliarity (32.9%) and healing concerns (25.9%). Confidence varied and 25% had never performed a REP. CONCLUSION: REPs are generally appropriately treatment planned, although more education with regards to clinical suitability and case selection is suggested. Geographical variance in provision of REPs is apparent between the UK and non-UK endodontists. Hesitancy exists in the provision of REPs, and prevalence of provision is low.

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