This cohort study focuses on establishing volumes and subclassifications of extended temporomandibular joint replacement (eTMJR) prostheses that are presently being produced compared to the production of standard TMJR devices. The reports of the use of eTMJR devices in the management of large segmental mandibular defects that also involve the temporomandibular joint (TMJ) are increasing in the literature. Data received from Stryker/TMJ Concepts reveals that eTMJR prostheses account for 13.5% of TMJR devices produced. The literature reports eTMJR adverse event issues such as infection, mechanical failures, and heterotopic bone formation. The aim of this study is to provide insights into the use of eTMJR prostheses to guide clinicians and researchers in advancing their use as a management option for complex mandibular reconstructions. Future research directions, focusing on the elements of device embodiments (materials, design, manufacturing), regenerative medicine, and predictive tools to enhance eTMJR longevity and success, are discussed.
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