Introduction Artificial intelligence (AI)-powered mobile applications (apps) like TestMyTeeth offer potential for at-home dental plaque screening.Objective To evaluate usability and user perceptions of the TestMyTeeth app for remote plaque detection.Methods A cross-sectional study with adult participants recruited using convenience sampling. Participants used the app and completed an online questionnaire including the system usability scale (SUS) and user experience items. Descriptive statistics summarised demographics and responses. SUS scores and non-parametric tests assessed usability differences across age, education level and sex.Results For 132 participants recruited (75% female; 90% under 44 years-old), the mean SUS score was 56.2 (standard deviation +/- 13.5; range: 10-85), indicating 'marginal' acceptability. Additionally, 54.6% were interested in frequent use, 41.6% found the app easy to use and 50% needed technical support. Participants found significant challenges capturing intra-oral photographs, especially for posterior teeth. No significant SUS score differences were found for age (p = 0.951), education level (p = 0.569), or sex (p = 0.154). Qualitative feedback highlighted benefits of self-monitoring but concerns about app complexity and accuracy without professional guidance.Conclusion The app shows potential for empowering at-home dental plaque screening but faces usability challenges. Improvements in user interface and photo-capture functionality would enhance usability.
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