Research Papers
AgNWs-COF SERS biosensor for oral cancer diagnosis based on exhaled breath and saliva.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy • 2026 • Vol. 344 (Pt 1)
Over recent years, surface-enhanced Raman spectroscopy (SERS) has shown its unparalleled sensitivity and molecular specificity in biomedical applications. However, noninvasive and sensitive detection…
Chen, Z; Huang, Y; Li, S
NIR-activated nanodisguisers for targeted bactericidal action and enhanced electron transfer in periodontitis treatment.
Biomaterials • 2026 • Vol. 324
Antibacterial treatment for periodontitis faces significant challenges due to the lack of selective bactericidal therapies. In this study, we developed multifunctional nanospheres encapsulated with F…
Ding, Q; Dong, B; Kim, J
Soft tissue integration around dental implants: A pressing priority.
Biomaterials • 2026 • Vol. 324
While osseointegration has traditionally been the focal point of dental implant design, recent research highlights the equally crucial role of establishing a resilient and biologically integrated sof…
Alexander, R; Liu, X
Clinical and dosimetric feasibility of sparing submandibular gland in patients with oral cavity squamous cell carcinoma.
Annals of medicine • 2025 • Vol. 57 (1)
BACKGROUND: To investigate the incidence of submandibular gland (SMG) involvement and explore the feasibility of sparing SMG in the oral cavity squamous cell carcinoma (OSCC). METHODS: This study ret…
Guan, L; He, Y; Wu, S
Chronic stress resulting from stressful life events and its role in the onset of primary Sjogren's syndrome: a comparative analysis using the modified Holmes-Rahe stress scale.
Stress (Amsterdam, Netherlands) • 2025 • Vol. 28 (1)
Recent years brought considerable attention to the connection between chronic stress and the development of autoimmune diseases. However, little is still known about the impact of prolonged stress re…
Chmielewski, M; Jaskolska, M; Jaskolski, D
Reproduction outcomes and prognostic significance of pregnancy after nasopharyngeal carcinoma treatment.
Annals of medicine • 2025 • Vol. 57 (1)
OBJECTIVE: Many female patients with nasopharyngeal carcinoma (NPC) desire to reproduce after treatment. To evaluate the outcomes of subsequent pregnancy after NPC and explore the prognostic effects …
Chen, Q; Guo, S; Li, X
Zinc-mediated metalloimmunotherapy with dual elimination of tumor and intratumoral bacteria in oral squamous cell carcinoma.
Biomaterials • 2025 • Vol. 323
Metal dyshomeostasis has been implicated in the immune evasion, host-microbiota interaction and tumor progression during carcinogenesis. Specifically, zinc dyshomeostasis has been observed in oral sq…
Chen, J; Cheng, B; Hui, Q
The effect of mumps vaccine on the incidence of mumps in Hefei: An interrupted time-series analysis.
Human vaccines & immunotherapeutics • 2025 • Vol. 21 (1)
To quantitatively assess the incremental protective effect of two-dose mumps vaccination in Hefei. Monthly mumps incidence during 2011-2023 were collected. The Interrupted Time Series and Segmented R…
Hou, L; Jin, Y; Qu, G
Advances in pH-responsive drug delivery systems for periodontitis treatment.
Drug delivery • 2025 • Vol. 32 (1)
Periodontitis is a prevalent and destructive inflammatory disease that is closely linked to various systemic conditions. In recent years, the local delivery of therapeutic agents via novel biomateria…
Chen, X; Gong, X; Li, X
Histine, carbohydrates/polysaccharides, and proteins with beta-sheet conformation as promising staging markers for oral squamous cell carcinoma.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy • 2025 • Vol. 340
Cancers of the oral cavity and lip ranks 15th cancer mortality being oral squamous cell carcinoma (OSCC) the predominant malignant neoplasm in the head and neck region. Liquid optical biopsy using in…
Alves, M; Bandeira, C; da Silva Martinho, H
Development and evaluation of a retrieval-augmented large language model framework for enhancing endodontic education.
International journal of medical informatics • 2025 • Vol. 203
BACKGROUND: Integrating domain-specific knowledge into large language models (LLMs) remains a critical challenge in medical education. In dental specialties such as endodontics, effective learning re…
Dong, Y; Li, J; Liu, S
Prototype design of porous Ti6Al4V intraosseous implant for use in mandibular reconstruction.
Journal of the mechanical behavior of biomedical materials • 2025 • Vol. 171
The design of patient-specific implants often requires computer simulations for the characterization of mechanical properties before manufacturing. We previously developed numerical models to predict…
Armstrong, J; Dixon, S; Hijazi, K
An exploration of molecular signaling in drug reprocessing for Oral Squamous Cell Carcinoma.
European journal of medicinal chemistry • 2025 • Vol. 295
The unique characteristics of cancer are crucial for comprehending the processes underlying cancer initiation, development, and maintenance. These hallmarks guide the development of novel therapeutic…
Afshari, A; Ghoflchi, S; Hosseini, H
Luteolin alleviates hyposalivation by upregulating AQP5 through binding to estrogen receptor beta and potentiating the saliva secretion signaling pathway.
European journal of pharmacology • 2025 • Vol. 1004
Xerostomia, common in postmenopausal women, is highly prevalent and significantly diminishes quality of life. However, effective clinical treatments with minimal side effects are limited. This study …
He, X; Li, J; Li, Y
Low IL-35 expression in CSF is associated with Neuro-Behcet Disease: Comparative analysis between parenchymal and Non-parenchymal NBD.
Immunology letters • 2025 • Vol. 275
BACKGROUND: IL-35 is a recently discovered immunoregulatory cytokine that inhibits inflammatory cytokines by suppressing their lineage-specific transcription factors. The objective of this study was …
Hamzaoui, A; Hamzaoui, K; Salhi, M
Panx3 mediates ferroptosis via the AKT/mTOR signaling pathway in oral squamous cell carcinoma.
Cellular signalling • 2025 • Vol. 134
Pannexin 3 (Panx3) has been the subject of numerous studies across different cell types, predominantly concentrating on bone remodeling, wound repair, and dermal inflammation. However, the link betwe…
Li, X; Liang, S; Liu, Y
Role of the CEACAM7-JAK2/STAT3-BST2 Axis in the migration of nasopharyngeal carcinoma cells.
Biochimica et biophysica acta. Molecular basis of disease • 2025 • Vol. 1871 (7)
OBJECTIVE: Nasopharyngeal carcinoma (NPC) is a rare malignancy of the head and neck, with recurrence and distant metastasis being the primary causes of mortality among affected patients. Carcinoembry…
Ho, Y; Hsin, C; Huang, C
Enamel remineralization enhancement by mesoporous bioactive glass (MBG) in commercial fluoride varnish and development of an MBG/fluoride chitosan composite hydrogel.
Colloids and surfaces. B, Biointerfaces • 2025 • Vol. 254
With its excellent bioactivity and mesoporosity that endows controlled release of chemical or biological cues, mesoporous bioactive glass (MBG) is widely used in bone regeneration, yet less recognize…
Guo, J; Lin, D; Yang, L
METTL1-mediated m7G modification of NEK1 mRNA promotes the proliferation of oral squamous cell carcinoma.
Biochimica et biophysica acta. Molecular basis of disease • 2025 • Vol. 1871 (7)
Oral squamous cell carcinoma (OSCC) is the most common malignant tumor found in the head and neck region, representing a significant public health concern. The 7-methylguanylate (m7G) RNA modificatio…
Chen, Y; Fu, B; Li, G
Cadmium(II) complexes with pyridine/dicarboxylic acid ligands as promising molecules for the treatment of oral candidiasis.
Journal of inorganic biochemistry • 2025 • Vol. 271
Overgrowth of Candida spp., known for its strong adhesion to biotic and abiotic surfaces, makes treatment difficult in denture stomatitis. To address this challenge, two novel cadmium(II) complexes c…
Casagrande, G; da Paz Costa Sauda, T; da Silva, D