Research Papers
Oral Health Status of the Elderly Population in Iran.
Clinical and experimental dental research • 2025 • Vol. 11 (4)
OBJECTIVES: To evaluate the oral, periodontal, and dental health of the elderly population of Iran. MATERIAL AND METHODS: This was a cross-sectional study as a part of the second wave of Birjand Long…
Alizadeh, L; Bijari, S; Darmiani, S
Comparison of Different Frameworks and Implant Angulations in All-On-Four and Six Concepts: A Finite Element Analysis.
Clinical implant dentistry and related research • 2025 • Vol. 27 (4)
OBJECTIVES: The study aimed to compare the biomechanical behaviors in the all-on-four and all-on-six concept prostheses of different framework materials (cobalt-chromium Co-Cr, titanium Ti, and polye…
Aydin, S; Korkmaz, C
Accuracy of Robotic Computer-Assisted Implant Surgery for Transcrestal Sinus Floor Elevation: A Retrospective Case Series Study.
Clinical implant dentistry and related research • 2025 • Vol. 27 (4)
AIM: To investigate the accuracy of robotic computer-assisted implant surgery (r-CAIS) for transcrestal sinus floor elevation (TSFE) with simultaneous implant placement. MATERIALS AND METHODS: Virtua…
Chen, J; Li, A; Li, P
Derivation and validation of the AJCC9V pathological stage classification for HPV-positive oropharyngeal carcinoma: a multicentre registry analysis.
The Lancet. Oncology • 2025 • Vol. 26 (8)
BACKGROUND: Modernisation of the American Joint Committee on Cancer and Union for International Cancer Control (AJCC/UICC) staging for HPV-positive oropharyngeal carcinoma has strengthened its fundam…
Branstetter, B; Evans, M; Ferris, R
Evaluation of Root Canal Cleaning and Irrigant Penetration Using Different Irrigation Protocols: A Combined SEM and Single-Tooth Micro-CT Study.
Clinical and experimental dental research • 2025 • Vol. 11 (4)
OBJECTIVES: This study evaluated the effectiveness of different irrigation techniques in removing debris and smear layers and in improving irrigant penetration within root canals. Particular attentio…
Abdellatif, D; Armogida, N; Cernera, M
Single-cell and spatial transcriptomics reveal mechanisms of radioresistance and immune escape in recurrent nasopharyngeal carcinoma.
Nature genetics • 2025 • Vol. 57 (8)
Radiotherapy resistance and immune evasion are prominent features of recurrent nasopharyngeal carcinoma (rNPC). However, their mechanisms remain incompletely understood. Here, we conducted single-cel…
Chen, K; Chen, M; Dong, K
A Study Investigating the Value of Using a Novel Mobile Application as an Adjunct to the Traditional Method of Diagnosing Periodontal Diseases.
Clinical and experimental dental research • 2025 • Vol. 11 (4)
BACKGROUND: Periodontal disease is a prevalent condition in the general population. An updated classification system in 2018 introduced major changes to how this disease is classified and has implica…
Honari, B; Maloney, B; Polyzois, I
Marginal Bone Level Changes in Full-Arch Rehabilitation: Digital Versus Analog Protocols-A 5-Year Retrospective Study.
Clinical implant dentistry and related research • 2025 • Vol. 27 (4)
INTRODUCTION: This retrospective study compares the clinical outcomes of analog impressions versus intraoral scanning in full-arch immediate loading rehabilitations. Specifically, it evaluates peri-i…
Caponio, V; De Angelis, N; Menini, M
A Multicenter Study of Factors Related to Early Implant Failures-Part 2: Patient Factors.
Clinical implant dentistry and related research • 2025 • Vol. 27 (4)
BACKGROUND: Recent advancements in dental implant materials, designs, and surgery have increased their use, especially for challenging local conditions. As guidelines for individualized risk assessme…
Hjalmarsson, L; Stenport, V; Wahlberg, R
Effect of Secondary Non-Thermal Plasma Decontamination on Ethanol-Treated Endosteal Implant Surfaces: An In Vivo Study of Osseointegration.
Journal of biomedical materials research. Part B, Applied biomaterials • 2025 • Vol. 113 (8)
Effective surface treatment of implants is essential for enhancing osseointegration outcomes. This study assessed the influence of alcohol decontamination both with and without secondary argon-based …
Brochu, B; Castellano, A; Coelho, P
Prevalence of dental anxiety and its associated factors among patients visiting tertiary care dental hospital in Kathmandu, Nepal: a cross-sectional study.
BMJ open • 2025 • Vol. 15 (7)
BACKGROUND: Dental anxiety, affecting 15.3% of adults globally, is more common in younger people and women. It often leads to avoiding dental visits, which worsens oral health. In Nepal, limited stud…
Kandel, K; Karn, K; Kumal, M
Single-cell spatial atlas of smoking-induced changes in human gingival tissues.
International journal of oral science • 2025 • Vol. 17 (1)
Smoking is a well-established risk factor for periodontitis, yet the precise mechanisms by which smoking contributes to periodontal disease remain poorly understood. Recent advances in spatial transc…
Gao, L; Ren, J; Shen, Z
Comparative analysis of fit, mechanical properties, and surface characteristics in subtractive- and additive-manufactured zirconia crowns.
BMC oral health • 2025 • Vol. 25 (1)
BACKGROUND: This study presents different zirconia additive manufacturing (AM) materials and technologies while assessing the fit, hardness, and shear bond strength of crowns produced by AM and subtr…
Cho, S; Chung, H; Ioannidis, A
Network control theory uncovers aberrant connectome controllability in trigeminal neuralgia.
The journal of headache and pain • 2025 • Vol. 26 (1)
BACKGROUND: Trigeminal neuralgia (TN) involves complex neural network alterations beyond the trigeminal system. Network Control Theory (NCT) offers a novel framework to quantify how brain network arc…
Chu, T; Gao, F; Peng, J
Boldine as a Potent Anticancer Agent: Induction of Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis via Inhibition of Notch Signaling in Human Oral Carcinoma Cells.
Journal of biochemical and molecular toxicology • 2025 • Vol. 39 (8)
In the present study, we investigated the anticarcinogenic potential of Boldine, a natural alkaloid, against human oral carcinoma KB and HEp-2 cell lines. Cytotoxicity was evaluated using the MTT ass…
Asath, N; Azhamuthu, T; Jaganathan, M
Suppression of Schwann Cell Ferroptosis Mitigates Demyelination and Trigeminal Neuropathic Pain in the IoN-CCI Model.
The European journal of neuroscience • 2025 • Vol. 62 (3)
Demyelination is widely acknowledged as the underlying pathological mechanism of trigeminal neuralgia (TN), while ferroptosis has been implicated in neurodegenerative disorders associated with demyel…
Chen, K; Dou, N; Hu, S
3D-guided grafting and implant reconstruction for severe oligodontia in an adolescent: a novel approach.
British dental journal • 2025 • Vol. 239 (3)
This paper outlines the case of a 16-year-old female patient with oligodontia, missing most of her permanent teeth, who was unhappy with her appearance and was embarrassed and felt socially inhibited…
Dawood, A; Fullerton, H; Harley, K
Rethinking Radiation Therapy for Perineural Invasion in Oral Cancer: Does More Coverage Improve Outcomes?
Cancer medicine • 2025 • Vol. 14 (15)
INTRODUCTION: Perineural invasion (PNI) in oral squamous cell carcinoma (OSCC) is linked to aggressive tumour behaviour and poorer survival outcomes. Adjuvant radiotherapy (RT) is recommended for PNI…
Adhau, A; Bal, M; Budrukkar, A
Impact of Immediate Dentin Sealing With Various Universal Adhesives on Shear Bond Strength of Dual-Cure Resin Cement.
Clinical and experimental dental research • 2025 • Vol. 11 (4)
OBJECTIVES: This study evaluated the effect of universal adhesives (UAs) applied as Immediate Dentin Sealing (IDS) on the shear bond strength (SBS) of dual-cure resin cement, both immediately and aft…
Janson, M; Liebermann, A; Schoppmeier, C
RANKL, OPG, and CTS-K Release in Bone Response to Immediate Nonfunctional Loading of a Single Implant in Mandibular Molar Sites During Osseointegration Establishment.
Clinical and experimental dental research • 2025 • Vol. 11 (4)
OBJECTIVES: To verify that osseointegration maturation under immediate restoration is correlative with active release of cytokines. MATERIAL AND METHODS: The participants needing the restoration of a…
Chen, X; Fan, Y; Hu, X