Research Papers

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REMINERALIZATION OF WHITE SPOT LESIONS IN PRIMARY TEETH USING AN INTENSIVE APPLICATION PROTOCOL OF CURODONT REPAIR FLUORIDE PLUS, MI VARNISH OR DURAPHAT VARNISH (RANDOMIZED CONTROLLED CLINICAL TRIAL).

The journal of evidence-based dental practice • 2025 • Vol. 25 (3)

OBJECTIVES: To evaluate the efficacy of intensive application of Curodont Repair Fluoride Plus (CRFP), MI varnish or Duraphat in treating white spot lesions (WSLs) of primary teeth over 12-months fol…

PMID: 40716822 PICO Pending DOI

Dowidar, K; Khairy, S; Talaat, D

Published: Sep 01, 2025
EFFICACY OF HYALURONIC NANOGEL SPRAY FOR TREATING DRY MOUTH: A RANDOMIZED CROSSOVER STUDY.

The journal of evidence-based dental practice • 2025 • Vol. 25 (3)

OBJECTIVES: To evaluate the efficacy of Hy-N spray in dry mouth patients. MATERIALS AND METHODS: A randomized double-blind crossover study was conducted on patients with dry mouth. They were given 3 …

PMID: 40716828 PICO Pending DOI

Bhalang, K; Eakpunyakul, N; Kopongpanich, P

Published: Sep 01, 2025
The Desensitizing Effect of Nanosilver Fluoride Compared to Photobiomodulation Therapy in Molar-Incisor Hypomineralization: A Randomized Clinical Trial.

The journal of evidence-based dental practice • 2025 • Vol. 25 (3)

OBJECTIVES: Molar-incisor hypomineralization (MIH) can cause hypersensitivity. This study compared nanosilver fluoride (NSF) and photobiomodulation therapy (PBMT) regarding desensitization in MIH-aff…

PMID: 40716831 PICO Pending DOI

Essawy, M; Nabil, N; Sharaf, A

Published: Sep 01, 2025
Suspected Feline Calicivirus Infection Triggering Ulcerative Oral and Skin Lesions in Cats Following Routine Ovariohysterectomy: A Postoperative Risk Assessment.

Veterinary medicine and science • 2025 • Vol. 11 (5)

Feline calicivirus (FCV) is a highly contagious pathogen prevalent in domestic cats, often leading to upper respiratory tract infections and oral diseases. In clinical settings, particularly veterina…

PMID: 40728089 PICO Pending DOI PMC

Akgul, G; Karakaya-Bilen, E; Yilmaz-Koc, O

Published: Sep 01, 2025
Racial Disparities in Quality of Dental Care Among Publicly Insured Children.

Medical care • 2025 • Vol. 63 (9)

BACKGROUND: Reducing oral health disparities requires identifying subgroups experiencing gaps in quality of dental care and the sizes of those gaps. This study measured magnitudes and trends of racia…

PMID: 40730339 PICO Pending DOI PMC

Choi, S; Fayyad, R; Normand, S

Published: Sep 01, 2025
Prediction of Speech Impairment in Patients Treated for Oral or Oropharyngeal Cancer Using Automatic Speech Analysis.

International journal of language & communication disorders • 2025 • Vol. 60 (5)

BACKGROUND: Perceptual evaluation of speech disorders produces scores that poorly predict the consequences of speech impairment on the communication abilities of patients treated for oral/oropharynge…

PMID: 40755165 PICO Pending DOI PMC

Balaguer, M; Farinas, J; Pinquier, J

Published: Sep 01, 2025
Potential effects of prebiotic fibers on dental caries: a systematic review.

Journal of the science of food and agriculture • 2025 • Vol. 105 (11)

Certain dietary fibers exhibit prebiotic effects on gut microbiota, but their influence on oral health remains unclear. This study conducted a systematic review across four databases to examine the p…

PMID: 39812321 PICO Pending DOI

Fernandez, C; Maturana-Valenzuela, C; Rojas-Castillo, N

Published: Aug 30, 2025
Alteration of immunomodulatory properties of locally applied gingival-derived mesenchymal stem cells by the oral inflammatory environment via Caspase-3/8 in periodontitis.

International immunopharmacology • 2025 • Vol. 161

OBJECTIVES: To investigate whether gingival tissue-specific mesenchymal stem cells exhibit relevant phenotypic features in the periodontal inflammatory microenvironment. METHODS: In this study, perio…

PMID: 40472777 PICO Pending DOI

Chen, Q; Duan, F; Gu, B

Published: Aug 28, 2025
Localized delivery of Aza-BODIPY photosensitizer using dissolvable microneedle patch to treat oral carcinoma.

International journal of pharmaceutics • 2025 • Vol. 681

The clinical application of photodynamic therapy (PDT) is limited by the phototoxicity of the photosensitizer. Localized application of photosensitizers can reduce the phototoxic effects and improve …

PMID: 40523547 PICO Pending DOI

Chakravarty, M; Kothari, R; Nag, A

Published: Aug 20, 2025
[Reversed halo sign as imaging manifestation of primary Sjogren's syndrome with nonspecific interstitial pneumonia].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases • 2025 • Vol. 48 (8)

The reversed halo sign (RHS), also referred to as the atoll sign, represents a distinct imaging finding that was initially characterized in cryptogenic organizing pneumonia and has subsequently been …

PMID: 40764139 PICO Pending DOI

Feng, T; Lin, C; Wang, S

Published: Aug 12, 2025
Micro-CT analysis of cement adaptation and porosity in 3D-Printed permanent resin crowns before and after chewing simulation.

Clinical oral investigations • 2025 • Vol. 29 (9)

OBJECTIVE: This study evaluates cementation gap, cement volume, and porosity levels in three-dimensional crown restorations using four permanent resin materials and printers, and examines changes aft…

PMID: 40789822 PICO Pending DOI

Arslan, E; Keles, A

Published: Aug 12, 2025
Dental lessons learned from large-scale military dental records in the Israel defense forces: military dentistry as a window into national oral health trends.

Israel journal of health policy research • 2025 • Vol. 14 (1)

Mandatory military service creates a unique opportunity to examine health patterns in a near-comprehensive national cohort of young adults. In this context, large-scale, routinely collected military …

PMID: 40790222 PICO Pending DOI PMC

Tobias, G; Zadik, Y

Published: Aug 12, 2025
Oesophageal Lichen Planus: Case Series and Review of the Literature.

Acta dermato-venereologica • 2025 • Vol. 105

Lichen planus affects 0.5% to 2% of the population. The involvement of the oesophagus is a rare manifestation with high morbidity and risk of malignancy. Clinical characteristics and diagnostic-thera…

PMID: 40787740 PICO Pending DOI

Iglesias, M; Manzanares, N; Molina-Alvarez, A

Published: Aug 11, 2025
Are dental magnetic resonance imaging and ultrasonography techniques reliable alternatives for treatment planning dental implants? A systematic review and meta-analysis.

International journal of implant dentistry • 2025 • Vol. 11 (1)

BACKGROUND: The rising global demand for dental implant highlights the necessity for precise imaging techniques that minimise patient risk of radiation exposure. While the cone -beam Computed Tomogra…

PMID: 40788371 PICO Pending DOI PMC

Donaldson, J; Neves, V; Scott, J

Published: Aug 11, 2025
The effect of flap advancement on bone graft displacement with or without membrane stabilization - a preclinical study.

BMC oral health • 2025 • Vol. 25 (1)

BACKGROUND: Displacement of bone graft materials following horizontal bone augmentation (HBA) procedures may compromise treatment outcomes, yet the role of flap tension remains unclear. This study ai…

PMID: 40790206 PICO Pending DOI PMC

Cafferata, E; Couso-Queiruga, E; Raabe, C

Published: Aug 11, 2025
Pseudomonas aeruginosa in dental unit waterlines: an emerging threat of virulence genes in healthcare-associated infections.

BMC oral health • 2025 • Vol. 25 (1)

INTRODUCTION: Pseudomonas aeruginosa is a leading cause of healthcare-associated infections (HAIs), especially in dental environments. In this study, we examine the prevalence of virulence factors in…

PMID: 40790577 PICO Pending DOI PMC

Emrani, N; Shafipour, M; Shahryari, A

Published: Aug 11, 2025
Malignant melanoma of the conjunctiva metastatic to the parotid gland: a case report.

Journal of medical case reports • 2025 • Vol. 19 (1)

BACKGROUND: Most malignant melanomas occurring in the parotid gland are presumed to be of metastatic origin from cutaneous, sporadically mucosal, or ocular primary sites in the head and neck region. …

PMID: 40790597 PICO Pending DOI PMC

Gamrot-Wrzol, M; Misiolek, M; Rogalska, M

Published: Aug 11, 2025
Mutant p53 confers chemoresistance by activating KMT5B-mediated DNA repair pathway in nasopharyngeal carcinoma.

Cancer letters • 2025 • Vol. 625

Nasopharyngeal carcinoma (NPC), a malignancy arising from the nasopharyngeal epithelium, is common in the east and southeast area of Asia. Treatments for locally advanced and recurrent NPC include ch…

PMID: 40316196 PICO Pending DOI

Bazer, D; Chiang, Y; Gingold, J

Published: Aug 10, 2025
Long-Term Follow-Up of E3311, an ECOG-ACRIN Cancer Research Group Phase II Trial of Transoral Surgery and Risk-Based Adjuvant Treatment in Human Papillomavirus-Initiated Oropharynx Cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2025 • Vol. 43 (23)

This phase II trial of transoral surgery (TOS) with deintensified postoperative management in human papillomavirus (HPV)-associated oropharynx cancer (OPC) enrolled patients with resectable cT1-2 sta…

PMID: 40493877 PICO Pending DOI PMC

Bell, R; Burtness, B; Ferris, R

Published: Aug 10, 2025
Primary Central Intraosseous Mucoepidermoid Carcinoma of the Mandible.

Head and neck pathology • 2025 • Vol. 19 (1)

Mucoepidermoid carcinoma (MEC) is the most common malignant tumor of the salivary glands. Rarely, MEC may arise primarily within the jaw bones as central intraosseous MEC, whose pathogenesis remains …

PMID: 40781173 PICO Pending DOI PMC

Araujo, F; Barros, A; de Vasconcelos Carvalho, M

Published: Aug 09, 2025
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