Research Papers

476343 papers found
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Craniofacial integration and modularity in untreated cleft lip and palate.

Clinical oral investigations • 2025 • Vol. 29 (4)

OBJECTIVES: To quantify craniofacial variation, integration, and modularity in untreated adults with orofacial clefts who had not undergone surgery, as well as in unaffected controls. MATERIALS AND M…

PMID: 40163241 PICO Pending DOI PMC

Fudalej, P; Kuijpers-Jagtman, A; Latief, B

Published: Mar 31, 2025
A systematic review and network meta-analysis of the association between periodontitis and inflammatory bowel diseases.

BMC oral health • 2025 • Vol. 25 (1)

OBJECTIVES: Several earlier studies have shown that IBD (including its two subtypes, ulcerative colitis (UC) and Crohn's disease (CD)) increases the risk of periodontal disease. This study aimed to e…

PMID: 40165211 PICO Pending DOI PMC

Ahmadi, M; Ahmadianghalehsorkh, M; Ayati, A

Published: Mar 31, 2025
Short-term cone beam CT study on bone mass changes post touch-controlled minimally invasive mandibular molar implant.

Scientific reports • 2025 • Vol. 15 (1)

This study aimed to investigate the change of peri-implant bone mass after touch-controlled, minimally invasive implantation in the mandibular first molar region by cone-beam computed tomography (CBC…

PMID: 40157911 PICO Pending DOI PMC

Han, W; Li, S; Li, W

Published: Mar 29, 2025
Effect of nanosecond laser assisted surface modification on physical and mechanical properties of denture base materials.

Scientific reports • 2025 • Vol. 15 (1)

Lasers are being used for modifying the surfaces of biomaterials to make them resistant to microbial adhesion. However, the effect of such surface modification on physical and mechanical properties h…

PMID: 40158027 PICO Pending DOI PMC

Daniel George, S; Ghurye, A; Ginjupalli, K

Published: Mar 29, 2025
Retinoic acid enhances gammadelta T cell cytotoxicity in nasopharyngeal carcinoma by reversing immune exhaustion.

Cell communication and signaling : CCS • 2025 • Vol. 23 (1)

Recent studies have shown that the antitumor immunity of adaptive immune cells is regulated by Vitamin A (retinoic acid, RA). However, it remains unclear whether RA and retinoic acid receptor (RAR) s…

PMID: 40158172 PICO Pending DOI PMC

Duan, H; Li, K; Li, P

Published: Mar 29, 2025
Salivary Interleukin-6 and Interleukin-18 Levels and Their Association with Dental Health in Children with Idiopathic Nephrotic Syndrome.

International journal of molecular sciences • 2025 • Vol. 26 (7)

Idiopathic nephrotic syndrome (NS) is associated with immune dysfunction and increased susceptibility to infections. Oral health may influence systemic inflammation and disease progression. This stud…

PMID: 40243946 PICO Pending DOI PMC

Korytowska-Przybylska, N; Olczak-Kowalczyk, D; Panczyk-Tomaszewska, M

Published: Mar 29, 2025
[Pleomorphic adenoma of the upper lip].

Swiss dental journal • 2025 • Vol. 135 (2)

A 48-year-old woman presented with a submucosal, slow-growing tumor of over 1.5 cm in the left upper lip. The enucleation was performed in local anesthesia and after a curved incision cranial to the …

PMID: 40151876 PICO Pending DOI

Stanowska, O; VGA, S

Published: Mar 28, 2025
Reliability of Ashley Howes analysis in evaluating expansion potential: a cone beam computed tomography study.

Clinical oral investigations • 2025 • Vol. 29 (4)

OBJECTIVES: In recent times orthodontic treatment trends has swung towards non -extraction treatment. The Ashley Howes analysis evaluates the possibility of expansion based on the apical base. The tr…

PMID: 40153094 PICO Pending DOI

Agrawal, B; Padmanabhan, S; Srinivasan, B

Published: Mar 28, 2025
Implant placement-associated tissue swelling: a digital three-dimensional and patient-based assessment.

Clinical oral investigations • 2025 • Vol. 29 (4)

OBJECTIVES: There is scarce evidence on immediate soft tissue and patient-reported outcome measures (PROMs) following implant surgery. This prospective study aimed to quantify post-implant placement …

PMID: 40153106 PICO Pending DOI

Dentino, A; Han, S; Kofina, V

Published: Mar 28, 2025
Microenvironment-based immunotherapy in oral cancer: a comprehensive review.

Medical oncology (Northwood, London, England) • 2025 • Vol. 42 (5)

Oral cancer, a prevalent form of head and neck malignancy, accounts for 4% of global cancer cases. The most common type, oral squamous cell carcinoma (OSCC), has a survival rate of about 50%. Even th…

PMID: 40153139 PICO Pending DOI

Afjadi, M; Eskandari-Yaghbastlo, A; Faghihinia, F

Published: Mar 28, 2025
Platelet-Rich Fibrin in MRONJ Management: A Prospective Comparative Study on Its Effectiveness in Prevention and Treatment.

Medicina (Kaunas, Lithuania) • 2025 • Vol. 61 (4)

Background and Objectives: Medication-related osteonecrosis of the jaw (MRONJ) was first recognized as a disease entity and reported in the literature in 2003. Within a few years, the incidence of MR…

PMID: 40282916 PICO Pending DOI PMC

Hum, I; Maracineanu, R; Motoc, M

Published: Mar 28, 2025
Periodontal pathogens as potential risk factors for systemic diseases: An overview.

Acta microbiologica et immunologica Hungarica • 2025 • Vol. 72 (1)

There is a plethora of evidence that suggests infection may either directly or indirectly trigger chronic inflammatory processes which may then act as a risk factor for diabetes mellitus and atherosc…

PMID: 40067380 PICO Pending DOI

Kodangala, S; Rao, A

Published: Mar 27, 2025
Atherogenic index of plasma and periodontitis in non-dyslipidemic adults: a nationwide study.

Clinical oral investigations • 2025 • Vol. 29 (4)

BACKGROUND: This study investigated the association between atherogenic index of plasma (AIP)-related indices and periodontal diseases in adults without dyslipidemia using healthcare big data from Ko…

PMID: 40140104 PICO Pending DOI

Chung, K; Kang, T; Kim, N

Published: Mar 27, 2025
Effectiveness of root canal therapy in auto-transplanted third molars: a systematic review, meta-analysis and case series report.

Clinical oral investigations • 2025 • Vol. 29 (4)

OBJECTIVES: The existing literature indicates insufficient conclusive evidence regarding the efficacy of root canal therapy (RCT) in conjunction with third molar autologous tooth transplantation (ATT…

PMID: 40146481 PICO Pending DOI PMC

Chen, Y; Chi, J; Guo, D

Published: Mar 27, 2025
Smoking impairs cognitive function through the mediating effect of periodontitis in older adults.

BMC psychiatry • 2025 • Vol. 25 (1)

OBJECTIVES: Evidence has shown that both smoking and periodontitis were linked to cognitive impairment. This study examines whether periodontitis mediates the effects of smoking status on cognitive f…

PMID: 40148790 PICO Pending DOI PMC

An, Y; Gao, J; Jin, Z

Published: Mar 27, 2025
Changing trends in oral mucosal diseases in China (2016-2024): a cross-sectional study of 316,166 patients with focus on COVID-19 impact and use of chinese patent medicines.

BMC oral health • 2025 • Vol. 25 (1)

BACKGROUND: Oral mucosal health is a critical component of overall oral health and impacts an individual's quality of life. Despite variations in prevalence rates of oral mucosal diseases across regi…

PMID: 40148866 PICO Pending DOI PMC

Chen, Y; Fang, J; Hua, H

Published: Mar 27, 2025
Management of deep carious lesions among Syrian dentists: a cross-sectional study.

BMC oral health • 2025 • Vol. 25 (1)

BACKGROUND: Deep carious lesions present significant challenges in dental practice, requiring effective management strategies to preserve tooth sensibility and function. This study aimed to assess Sy…

PMID: 40148883 PICO Pending DOI PMC

Alghorani, R; Alhaffar, M; Banerjee, A

Published: Mar 27, 2025
Evaluation of dentinal crack formation during post space preparation using different fiber post systems with micro-computed tomography.

BMC oral health • 2025 • Vol. 25 (1)

BACKGROUND: This study used micro-computed tomography (microCT) to assess the post space preparation systems [Rebilda (VOCO), RelyX (3M)] and preparations of varying lengths to create root dentin cra…

PMID: 40148885 PICO Pending DOI PMC

Kirici, D; Kusucar, A

Published: Mar 27, 2025
Validation and development of a refined M1 category for nasopharyngeal carcinoma based on the version-nine of AJCC/UICC TNM staging system in the immunotherapy era: A multicenter cohort study.

European journal of cancer (Oxford, England : 1990) • 2025 • Vol. 219

OBJECTIVE: To evaluate the applicability of the M1 category of the version-nine of AJCC/UICC TNM staging system (TNM-9) for M1 nasopharyngeal carcinoma (M1-NPC) in immunotherapy era and propose poten…

PMID: 39954311 PICO Pending DOI

Chen, X; Gong, X; Guo, Q

Published: Mar 26, 2025
ACLY inhibitor reduced Porphyromonas gingivalis-induced pyroptosis by suppressing microtubules acetylation in macrophages.

International immunopharmacology • 2025 • Vol. 150

OBJECTIVES: This study aimed to investigate the effect of acetylation of alpha-tubulin induced by ATP-citrate lyase (ACLY) activation on pyroptosis process in mouse bone marrow derived macrophages (B…

PMID: 39955916 PICO Pending DOI

Guo, F; Jiang, K; Lei, L

Published: Mar 26, 2025
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