Research Papers

476343 papers found
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The biological function and diagnostic value of miR-762 in nasopharyngeal carcinoma.

Journal of the Chinese Medical Association : JCMA • 2021 • Vol. 84 (5)

BACKGROUND: Low diagnostic efficiency and high metastasis and recurrence of nasopharyngeal carcinoma (NPC) result in bad survival. A novel diagnostic biomarker is of great importance for the improvem…

PMID: 33742996 PICO Pending DOI

Bao, L; Ji, K; Li, D

Published: May 01, 2021
A case-control study of topical and supplemental fluoride use and osteosarcoma risk.

Journal of the American Dental Association (1939) • 2021 • Vol. 152 (5)

BACKGROUND: A relationship between fluoride and osteosarcoma has been hypothesized but not validated. To the authors' knowledge, there are no published studies examining topical fluoride or dietary f…

PMID: 33745682 PICO Pending DOI PMC

Burgard, S; Couper, D; Douglass, C

Published: May 01, 2021
Repair of aged polymer-based CAD/CAM ceramics treated with different bonding protocols.

The International journal of prosthodontics • 2021 • Vol. 34 (3)

PURPOSE: The aim of this study was to compare the microtensile bond strength (muTBS) of different CAD/CAM polymer-based ceramics to a repair composite resin using various bonding protocols. MATERIALS…

PMID: 33750995 PICO Pending DOI

Bayazit, E

Published: May 01, 2021
Tanshinone IIA regulates microRNA‑125b/foxp3/caspase‑1 signaling and inhibits cell viability of nasopharyngeal carcinoma.

Molecular medicine reports • 2021 • Vol. 23 (5)

Nasopharyngeal carcinoma (NPC) is a common disease with high prevalence worldwide, affecting hundreds of thousands of patients every year. Although its progress can be inhibited by concurrent chemora…

PMID: 33760137 PICO Pending DOI PMC

Jin, W; Wang, J; Wang, Y

Published: May 01, 2021
Insight into the roles of melatonin in bone tissue and bone‑related diseases (Review).

International journal of molecular medicine • 2021 • Vol. 47 (5)

Bone‑related diseases comprise a large group of common diseases, including fractures, osteoporosis and osteoarthritis (OA), which affect a large number of individuals, particularly the elderly. The p…

PMID: 33760138 PICO Pending DOI PMC

Chen, G; Chen, L; Huang, X

Published: May 01, 2021
Galectin‑3 facilitates the proliferation and migration of nasopharyngeal carcinoma cells via activation of the ERK1/2 and Akt signaling pathways, and is positively correlated with the inflammatory state of nasopharyngeal carcinoma.

Molecular medicine reports • 2021 • Vol. 23 (5)

Nasopharyngeal carcinoma (NPC) is an epithelial carcinoma originating from the nasopharyngeal mucosal tissue and is highly prevalent in southeast Asia. Galectin‑3 (gal‑3) serves crucial roles in many…

PMID: 33760180 PICO Pending DOI PMC

Chai, J; Chen, Y; Li, M

Published: May 01, 2021
LUCAT1 as an oncogene in tongue squamous cell carcinoma by targeting miR-375 expression.

Journal of cellular and molecular medicine • 2021 • Vol. 25 (10)

Emerging studies suggested that lncRNAs play a crucial molecular role in cancer development and progression. LncRNA LUCAT1 has been proved as oncogenic molecular in lung cancer, glioma, osteosarcoma,…

PMID: 33787082 PICO Pending DOI PMC

Gong, Z; Wang, Q; Zhang, K

Published: May 01, 2021
The role of illicit drugs in developing medication-related osteonecrosis (MRONJ): a systematic review.

The British journal of oral & maxillofacial surgery • 2021 • Vol. 59 (4)

Medication-related osteonecrosis of the jaw (MRONJ) is a challenging condition to treat. It has primarily been associated with anti-resorptive and anti-angiogenic drugs, which are increasingly being …

PMID: 33789811 PICO Pending DOI

Akintola, O; Ball, R; Barry, E

Published: May 01, 2021
Accuracy of surface-guided patient setup for conventional radiotherapy of brain and nasopharynx cancer.

Journal of applied clinical medical physics • 2021 • Vol. 22 (5)

PURPOSE: To evaluate the accuracy of surface-guided radiotherapy (SGRT) in cranial patient setup by direct comparison between optical surface imaging (OSI) and cone-beam computed tomography (CBCT), b…

PMID: 33792186 PICO Pending DOI PMC

Aristophanous, M; Ballangrud, A; Cervino Arriba, L

Published: May 01, 2021
Comparison of subgingival and gingival margin plaque microbiota from dogs with healthy gingiva and early periodontal disease.

Research in veterinary science • 2021 • Vol. 136

The purpose of the investigation was to determine whether canine gingival margin (GM) plaque is a reliable surrogate for subgingival (SG) plaque from a microbial community (microbiota) perspective. S…

PMID: 33799170 PICO Pending DOI

Cawthrow, A; Haydock, R; Holcombe, L

Published: May 01, 2021
Generation of an iPSC line (CRICKi001-A) from an individual with a germline SMARCA4 missense mutation and autism spectrum disorder.

Stem cell research • 2021 • Vol. 53

Germline missense mutations in the BAF swi/snf chromatin remodeling subunit SMARCA4 are associated with neurodevelopmental disorders, including Coffin Siris Syndrome (CSS). Here, we generated an indu…

PMID: 33799280 PICO Pending DOI PMC

Devito, L; Dias, C; Guillemot, F

Published: May 01, 2021
Rare tumors: Retinoblastoma, nasopharyngeal cancer, and adrenocorticoid tumors.

Pediatric blood & cancer • 2021 • Vol. 68 Suppl 2

The role of surgery, chemotherapy, and radiation therapy for retinoblastoma has evolved considerably over the years with the efficacy of intraarterial chemotherapy and the high incidence of secondary…

PMID: 33818883 PICO Pending DOI

Bradley, K; Buchsbaum, J; Chuba, P

Published: May 01, 2021
Screening and identification of autophagy-related biomarkers for oral squamous cell carcinoma (OSCC) via integrated bioinformatics analysis.

Journal of cellular and molecular medicine • 2021 • Vol. 25 (9)

Increasing evidences have showed that autophagy played a significant role in oral squamous cell carcinoma (OSCC). Purpose of our study was to explore the prognostic value of autophagy-related genes (…

PMID: 33837652 PICO Pending DOI PMC

Gao, H; Huang, G; Lu, Z

Published: May 01, 2021
Post-operative pain management in dental implant surgery: a systematic review and meta-analysis of randomized clinical trials.

Clinical oral investigations • 2021 • Vol. 25 (5)

PURPOSE: To evaluate the clinical efficacy of various analgesic medications in mitigating orofacial pain following dental implant surgery. MATERIALS AND METHODS: A systematic search was conducted to …

PMID: 33839939 PICO Pending DOI

Alrajhi, M; Braun, R; Fatima, S

Published: May 01, 2021
Induction chemotherapy with lobaplatin and fluorouracil versus cisplatin and fluorouracil followed by chemoradiotherapy in patients with stage III-IVB nasopharyngeal carcinoma: an open-label, non-inferiority, randomised, controlled, phase 3 trial.

The Lancet. Oncology • 2021 • Vol. 22 (5)

BACKGROUND: Cisplatin-based induction chemotherapy plus concurrent chemoradiotherapy in the treatment of patients with locoregionally advanced nasopharyngeal carcinoma has been recommended in the Nat…

PMID: 33857411 PICO Pending DOI

Bai, Y; Cao, K; Cao, X

Published: May 01, 2021
A Novel Competence Pathway in the Oral Pathogen Streptococcus sobrinus.

Journal of dental research • 2021 • Vol. 100 (5)

Streptococcus sobrinus is an etiologic cause of dental caries (tooth decay) in humans. Our knowledge of S. sobrinus is scant despite the organism's important role in oral health. It is widely believe…

PMID: 33876976 PICO Pending DOI PMC

Jensen, P; Li, J; Wyllie, R

Published: May 01, 2021
Establishment of Pulp Damage Repair Models in Miniature Pigs Using Diode Lasers.

Photobiomodulation, photomedicine, and laser surgery • 2021 • Vol. 39 (5)

Objective: To establish a controlled pulp damage repair model in miniature pigs by using a diode laser. Background: Laser is a novel kind of controllable energy, and it is widely used in dentistry. M…

PMID: 33885356 PICO Pending DOI

Cheng, Q; Hong, J; Ma, Z

Published: May 01, 2021
The Nasoalveolar Molding Cleft Protocol: Long-Term Treatment Outcomes from Birth to Facial Maturity.

Plastic and reconstructive surgery • 2021 • Vol. 147 (5)

BACKGROUND: The authors present outcomes analysis of the nasoalveolar molding treatment protocol in patients with a cleft followed from birth to facial maturity. METHODS: A single-institution retrosp…

PMID: 33890899 PICO Pending DOI

Cutting, C; Flores, R; Grayson, B

Published: May 01, 2021
[Geographic analyses as a foundation for evidence-based public health interventions: the example identification and typology of risk clusters for mumps, measles, and rubella].

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz • 2021 • Vol. 64 (5)

BACKGROUND: Ideally, health services and interventions to improve immunization rates should be tailored to local target populations, such as spatial clusters. However, to date, little attention has b…

PMID: 33891131 PICO Pending DOI PMC

Hammerschmidt, R; Spura, A; Volker, S

Published: May 01, 2021
Outcomes and prognostic factors of apical periodontitis by root canal treatment and endodontic microsurgery-a retrospective cohort study.

Annals of palliative medicine • 2021 • Vol. 10 (5)

BACKGROUND: The aim of this study was to analyze the outcome and prognostic factors of root canal treatment (RCT) and endodontic microsurgery (EMS) in the treatment of apical periodontitis (AP), resp…

PMID: 33894717 PICO Pending DOI

Chen, X; Liu, S; Liu, W

Published: May 01, 2021
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