Research Papers
CD8+ T Cell Infiltration Predicts Chemoradiosensitivity in Nasopharyngeal or Oropharyngeal Cancer.
The Laryngoscope • 2021 • Vol. 131 (4)
OBJECTIVES: Limited information exists regarding the associations between pre-existing immune parameters in the tumor immune microenvironment (TIM) and either chemoradiosensitivity or prognosis for p…
Akiba, J; Chitose, S; Kakuma, T
Stress distribution within the ceramic veneer-tooth system with butt joint and feathered edge incisal preparation designs.
Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] • 2021 • Vol. 33 (3)
OBJECTIVE: This in-vitro study aims to study the stress distribution within the ceramic veneer-tooth system with two incisal preparation designs-butt joint (BJ) and feathered edge (FE), and to correl…
Aarts, J; Bennani, V; Chai, S
Short-term outcomes of induction chemotherapy with docetaxel, cisplatin, and fluorouracil (TPF) in locally advanced nasopharyngeal carcinoma.
Investigational new drugs • 2021 • Vol. 39 (2)
There is an unmet need for improving survival outcomes of locally advanced nasopharyngeal carcinoma, for example, T4/ N3 stage disease. To this end, we administered induction chemotherapy (IC) with T…
Honma, Y; Ikeda, A; Itami, J
An Exploratory Study of Speech and Language Therapy Intervention for Children Born With Cleft Palate +/- Lip.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association • 2021 • Vol. 58 (4)
INTRODUCTION: Children born with a cleft palate +/- lip are at risk of developing speech and language difficulties, which may require intervention from a speech and language therapist (SLT). To date,…
Harding, S; Williams, C; Wren, Y
Xerostomia and COVID-19: Unleashing Pandora's Box.
Ear, nose, & throat journal • 2021 • Vol. 100 (2_suppl)
Saniasiaya, J
Is systemic inflammation a missing link between periodontitis and hypertension? Results from two large population-based surveys.
Journal of internal medicine • 2021 • Vol. 289 (4)
OBJECTIVE: The primary objective was to investigate the relationship between periodontitis and hypertension in two independent large surveys. The secondary objective was to ascertain whether systemic…
Czesnikiewicz-Guzik, M; D'Aiuto, F; Guzik, T
[Clear resection margins to avoid escalation of adjuvant therapy in oropharyngeal squamous cell carcinoma].
HNO • 2021 • Vol. 69 (4)
BACKGROUND: Resection margins in patients with oropharyngeal squamous cell carcinoma (OPSCC) are a predictive marker for overall survival (OS) and recurrence-free interval (RFI). Adjuvant therapy is …
Backes, C; Becker, C; Hofauer, B
Effect of mineral trioxide aggregate plug location on root development in regenerative endodontic procedure.
Odontology • 2021 • Vol. 109 (2)
This retrospective study investigated the effect of mineral trioxide aggregate (MTA) plug location on treatment outcome and root maturation after regenerative endodontic procedures (REP) in immature …
Baek, S; Chun, K; Jun, J
A randomized crossover study on the effects of a custom-made mouthguard on cardiopulmonary parameters and cortisol differences in a validated handball specific course.
Injury • 2021 • Vol. 52 (4)
BACKGROUND: The importance of mouthguards for handball players has been proven however, most players are reluctant to use it. The impact on physical capacity is assessed heterogeneously in the litera…
Busse, M; Falz, R; Kwast, S
A survey of current trends in root canal treatment: access cavity design and cleaning and shaping practices.
Australian endodontic journal : the journal of the Australian Society of Endodontology Inc • 2021 • Vol. 47 (1)
The purpose of this study was to evaluate current trends in access cavity design and cleaning and shaping among endodontists. A survey was e-mailed to active members of the American Association of En…
Arias, A; Dunlap, C; Peters, O
Tissue-specific analysis of Fgf18 gene function in palate development.
Developmental dynamics : an official publication of the American Association of Anatomists • 2021 • Vol. 250 (4)
BACKGROUND: Previous studies showed that mice lacking Fgf18 function had cleft palate defects and that the FGF18 locus was associated with cleft lip and palate in humans, but what specific roles Fgf1…
Imamura, T; Jiang, R; Lan, Y
Selective Retreatment and Sinus Lift: An Alternative Approach to Surgically Manage the Palatal Roots of Maxillary Molars.
Journal of endodontics • 2021 • Vol. 47 (4)
Endodontic microsurgery on the palatal root of maxillary molars presents a clinical challenge because of the root position and approximation from the maxillary sinus floor. Attempting a buccal or a p…
Azim, A; Serebro, M; Wang, H
Guided Endodontic Access in a Maxillary Molar Using a Dynamic Navigation System.
Journal of endodontics • 2021 • Vol. 47 (4)
The treatment of calcified root canals is challenging in endodontic practice. A 63-year-old man was referred to the postgraduate endodontic clinic at the University of Maryland School of Dentistry, B…
Dianat, O; Gupta, S; Mostoufi, B
[De-escalation concepts for chemoradiotherapy of HPV-positive oropharyngeal carcinomas: pros and cons].
HNO • 2021 • Vol. 69 (4)
BACKGROUND: In contrast to alcohol- and nicotine-induced head and neck tumors, human papillomavirus (HPV)-positive oropharyngeal carcinoma rather affects younger patients, and the incidence of this e…
Nicolay, N; Ruhle, A
mTOR Inhibition Ablates Cisplatin-Resistant Salivary Gland Cancer Stem Cells.
Journal of dental research • 2021 • Vol. 100 (4)
Patients with advanced salivary gland mucoepidermoid carcinoma (MEC) are treated with surgery and radiotherapy, as current systemic therapies are largely ineffective. As such, current treatment frequ…
Nakano, T; Nor, J; Oklejas, A
Epithelial-to-mesenchymal transition in oral squamous cell carcinoma: Challenges and opportunities.
International journal of cancer • 2021 • Vol. 148 (7)
Oral squamous cell carcinoma (OSCC) is the most common malignancy representing 90% of all forms of oral cancer worldwide. Although great efforts have been made in the past decades, the 5-year surviva…
Cheng, B; Ling, Z; Tao, X
Allogenic stem cell transplant-associated acute graft versus host disease: a computational drug discovery text mining approach using oral and gut microbiome signatures.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer • 2021 • Vol. 29 (4)
PURPOSE: Acute graft versus host disease (aGVHD) is a major cause of non-relapse morbidity and mortality post-allogenic hematopoietic stem cell transplant (HSCT). Using conventional literature search…
Bahrani Mougeot, F; Beckman, M; Morton, D
Comparison of two curing protocols during adhesive cementation: can the step luting technique supersede the traditional one?
Odontology • 2021 • Vol. 109 (2)
This study aims to compare the degree of conversion of two different curing protocols used during adhesive cementation. The following resin luting agents were tested: Hri Flow (MF) and pre-heated Hri…
Conti, C; Monterubbianesi, R; Orilisi, G
A Case of Ramsay Hunt Syndrome That Began with Vestibular Symptoms: A Great Mimicker.
The American journal of medicine • 2021 • Vol. 134 (4)
Shimizu, T; Yokose, M
Reducing antibiotic prescriptions in children is not associated with higher rate of complications.
European journal of pediatrics • 2021 • Vol. 180 (4)
Acute otitis media (AOM) and sore throat are common reasons for antibiotic prescription in children. Starting from 2007, evidence-based guidelines and other multifaceted improvement activities (ProBA…
Barbieri, L; Buttazzi, R; Di Mario, S