Research Papers
Fecal microbiota and genetics in pediatric-onset orofacial granulomatosis and Crohn s disease.
Scientific reports • 2025 • Vol. 15 (1)
Orofacial granulomatosis (OFG) is a rare chronic inflammatory condition. It is under debate, whether it is a condition of its own or merely a subtype of Crohn's disease (CD). We aimed to search for m…
Agrawal, N; Alapulli, H; de Vos, W
Dimensional accuracy of additive and subtractive manufactured ceramic-reinforced hybrid composite inlays: a CBCT-based in vitro study.
Scientific reports • 2025 • Vol. 15 (1)
The dimensional accuracy of digitally processed inlays is often questioned because of inherent manufacturing inconsistencies associated with computer-aided design and manufacturing (CAD/CAM). This st…
Almasoudi, S; Chaurasia, A; Chourasia, H
A novel methodology for detecting separated endodontic instruments using a combination of algorithms in post-processing CBCT software.
Scientific reports • 2025 • Vol. 15 (1)
Separated endodontics instruments and high-density obturating materials produce metal artifacts on cone-beam computed tomography (CBCT) scans. This study evaluated a novel methodology to detect separ…
Azevedo, B; Bueno, M; de Sousa, V
Assessment of two methods for detecting carious dentin: an in vitro study.
BMC oral health • 2025 • Vol. 25 (1)
BACKGROUND: The objective of this study was to compare, in vitro, two dentinal caries lesion detector methods, Caries Finder and BlueCheck, to determine if they were substantially equivalent in their…
Jensen, R; Jenson, L; Kukreti, P
Modulatory role of exogenous arachidonic acid in periodontitis with type 2 diabetes mellitus mice.
BMC oral health • 2025 • Vol. 25 (1)
BACKGROUND: Type 2 diabetes mellitus (T2DM) exhibits a bidirectional relationship with periodontitis, wherein each condition influences the progression of the other. Arachidonic acid (AA) exerts an a…
Chen, X; Gong, H; He, Y
Development and validation of risk-predicting model for oral frailty in older adults patients with stroke.
BMC oral health • 2025 • Vol. 25 (1)
OBJECTIVE: This study aimed to construct a nomogram predicting oral frailty risk in Older adults patients with stroke. DESIGN: A cross-sectional study. METHODS: We selected 664 hospitalised older adu…
Fan, X; Li, Z; Ma, R
[Clinical efficacy of clear aligner treatment for pathologically migrated teeth in the anterior region of patients with severe periodontitis].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences • 2025 • Vol. 57 (1)
OBJECTIVE: To evaluate the clinical efficacy of clear aligner therapy in patients with severe periodontitis accompanied by pathological tooth displacement in the anterior region. METHODS: This retros…
Jiao, J; Li, J; Shi, J
[Microneedle combined with photodynamic therapy in the treatment of oral leukoplakia].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences • 2025 • Vol. 57 (1)
OBJECTIVE: To explore whether microneedle pretreatment can significantly improve the efficacy and safety of 5-aminolevulinic acid (ALA)-photodynamic therapy (PDT) in the treatment of oral leukoplakia…
Han, Y; Liu, H; Zhao, P
[Clinical application and three-dimensional finite element analysis of along-axis extraction method in mandibular mesial and horizontally impacted third molar surgery].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences • 2025 • Vol. 57 (1)
OBJECTIVE: To investigate the clinical application effect of the along-axis extraction method in the extraction of impacted mandibular third molars (IMTM) and to compare the biomechanical characteris…
Duan, D; Liu, M; Wang, E
[Characteristics of occlusal force and contact in 20 individual normal occlusion children with mixed dentition].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences • 2025 • Vol. 57 (1)
OBJECTIVE: To measure and analyze the occlusal force and contact in children with mixed dentition, and to preliminarily provide baseline data on the occlusion of individual normal occlusion children …
Jin, Y; Liao, P; Wang, Y
[Development and validation of a clinical automatic diagnosis system based on diagnostic criteria for temporomandibular disorders].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences • 2025 • Vol. 57 (1)
OBJECTIVE: To develop a clinical automated diagnostic system for temporomandibular disorders (TMD) based on the diagnostic criteria for TMD (DC/TMD) to assist dentists in making rapid and accurate cl…
Fang, Y; Fu, K; Lei, J
Advanced image-identified extranodal extension of retropharyngeal lymph nodes in the refinement of N classification for nasopharyngeal carcinoma.
Cell reports. Medicine • 2025 • Vol. 6 (2)
Advanced extranodal extension (ENE) in cervical lymph nodes (CLNs) increases the risk of distant metastasis in nasopharyngeal carcinoma (NPC). The 9th NPC staging system classifies N1/N2 patients wit…
Chen, L; Cui, C; Du, X
Hydrogels in Oral Disease Management: A Review of Innovations in Drug Delivery and Tissue Regeneration.
Medical science monitor : international medical journal of experimental and clinical research • 2025 • Vol. 31
The oral cavity is an open and complicated structure with a variety of factors affecting topical oral medications. The complicated physical and chemical surroundings of the oral cavity can influence …
Dapeng, M; Dongwen, L; Jiazhi, Y
Meteorin-like levels of oral fluids in periodontal health and diseases: a comparative cross-sectional study.
Clinical oral investigations • 2025 • Vol. 29 (2)
OBJECTIVES: Cytokines are critical role in the pathogenesis of periodontal diseases. Meteorin-like (Metrnl), a protein released in the oral mucosa, is a novel cytokine associated with various inflamm…
Koseoglu, S; Saglam, E; Saglam, M
Daytime sleepiness estimated using the Karolinska Sleepiness Scale during mandibular advancement device therapy for snoring and sleep apnea: a secondary analysis of a randomized controlled trial.
Sleep & breathing = Schlaf & Atmung • 2025 • Vol. 29 (1)
PURPOSE: The effect of mandibular advancement device therapy on daytime sleepiness remains unclear. Here, we evaluate the effect of a mandibular advancement device on daytime sleepiness using the Kar…
Carlberg, B; Forsgren, L; Franklin, K
Substance use during pregnancy and childhood dental caries: a Brazilian cohort study.
Scientific reports • 2025 • Vol. 15 (1)
This study aimed to evaluate the association between substance use during pregnancy (SUDP) and dental caries considering the Tooth Development Hypothesis and the Behavioral Hypothesis. This is a Braz…
Alves, C; Costa, E; de Sousa, F
A rare case of lingual mucosal leishmaniasis caused by reactivation of Leishmania infantum infection.
BMC infectious diseases • 2025 • Vol. 25 (1)
BACKGROUND: Leishmania infantum is the only prevalent Leishmania species in Europe and manifesting predominantly as cutaneous or visceral leishmaniasis, whereas new world species like Leishmania (L.)…
Eggers, Y; Feldt, T; Hammacher, A
The influence of different factors on the bond strength of lithium disilicate-reinforced glass-ceramics to Resin: a machine learning analysis.
BMC oral health • 2025 • Vol. 25 (1)
BACKGROUND: To assess the influence of various factors on the bond strength of glass-based ceramics and develop a model that can predict the bond strength values using machine learning (ML). METHODS:…
Chen, C; Chen, D; Liu, J
Relationship between bone mineral density and oral health: a cross sectional observational study.
BMC oral health • 2025 • Vol. 25 (1)
PURPOSE: Bone mineral density (BMD) is related to oral health. This study investigated how changes in BMD influence tooth loss risk and dental caries prevalence. METHODS: This cross-sectional observa…
Erdem, M; Erdem, R; Karakaya, K
High IgG titers against EBV glycoprotein 42 correlate with lower risk of nasopharyngeal carcinoma.
The Journal of clinical investigation • 2025 • Vol. 135 (4)
Serologic biomarkers for the early diagnosis of EBV-associated nasopharyngeal carcinoma (NPC) have been identified from population studies, but a protective antibody signature in cancer-free seroposi…
Shair, K; Warner, B