Research Papers
Immune Response Targeting Sjogren's Syndrome Antigen Ro52 Suppresses Tear Production in Female Mice.
International journal of molecular sciences • 2018 • Vol. 19 (10)
Autoantibodies reactive against Ro52 are present in 70% of Sjogren's syndrome patients and are associated with higher disease severity. However, their role in causing aqueous deficient dry eye, a maj…
Bagavant, H; Deshmukh, U; Papinska, J
Idiopathic macrocheilia.
BMJ case reports • 2018 • Vol. 2018
A 13-year-boy presented with painless swelling of upper and lower lips accompanied with gingival enlargement. The aetiology for these symptoms included vast pathological varieties but none of them co…
Pandya, H; Patel, H; Purani, J
Evaluation of Volume of Nasopharyngeal Cancers by the Cavalieri Principle.
Asian Pacific journal of cancer prevention : APJCP • 2018 • Vol. 19 (9)
Prediction of tumor volume using the Cavalieri method may be helpful in management of therapy and evaluation of treatment results. The aim of this study was to adapt the Cavalieri stereological metho…
Ozmen, H; Tatar, A; Yoruk, O
Polydopamine Nanoparticles as Efficient Scavengers for Reactive Oxygen Species in Periodontal Disease.
ACS Nano • 2018 • Vol. 12 (9)
Antioxidative therapy has been considered an efficient strategy for the treatment of a series of excessive reactive oxygen species (ROS)-triggered diseases, including oxidative-stress-induced periodo…
Bao, X; Hu, M; Sun, J
Development and validation of an endoscopic images-based deep learning model for detection with nasopharyngeal malignancies.
Cancer communications (London, England) • 2018 • Vol. 38 (1)
BACKGROUND: Due to the occult anatomic location of the nasopharynx and frequent presence of adenoid hyperplasia, the positive rate for malignancy identification during biopsy is low, thus leading to …
Cao, K; Chen, M; Chen, Q
In vitro and clinical evaluation of optical coherence tomography for the detection of subgingival calculus and root cementum.
Journal of oral science • 2018 • Vol. 60 (3)
This study evaluated the effectiveness of swept-source optical coherence tomography (ss-OCT) for detecting calculus and root cementum during periodontal therapy. Optical coherence tomography (OCT) im…
Akizuki, T; Aoki, A; Ejiri, K
Nanofilled and conventional resin-modified glass ionomer fillings combined with connective tissue grafts for treatment of gingival recessions with non-carious cervical lesions.
Journal of oral science • 2018 • Vol. 60 (3)
The aim of this study was to evaluate the clinical root coverage results of subepithelial connective tissue grafts (SCTG) performed on teeth with gingival recessions and non-carious cervical lesions …
Akalin, F; Dursun, C; Dursun, E
The molecular mechanisms of increased radiosensitivity of HPV-positive oropharyngeal squamous cell carcinoma (OPSCC): an extensive review.
Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale • 2018 • Vol. 47 (1)
Head and neck carcinomas (HNCs) collectively are the sixth most common cancer with an annual incidence of about 400,000 cases in the US. The most well-established risk factors for HNCs are tobacco an…
Kokot, N; Liu, C; Mann, D
Increased risk of aortic aneurysm and dissection in patients with Sjogren's syndrome: a nationwide population-based cohort study in Taiwan.
BMJ open • 2018 • Vol. 8 (9)
OBJECTIVES: Sjogren's syndrome (SS) is a systemic autoimmune disorder. Several molecular pathways and the activation of matrix metalloproteinases associated with the pathogenesis of SS participate in…
Chen, S; Chien, W; Chu, S
Molecular and cellular characterizations of human cherubism: disease aggressiveness depends on osteoclast differentiation.
Orphanet journal of rare diseases • 2018 • Vol. 13 (1)
BACKGROUND: Cherubism is a rare autosomal dominant disorder of the jaws caused by mutation of the SH3BP2 gene. The bone is replaced by a fibrous granuloma containing multinucleated giant cells. Cells…
Badoual, C; Berdal, A; Coudert, A
Integrated genomic analyses in PDX model reveal a cyclin-dependent kinase inhibitor Palbociclib as a novel candidate drug for nasopharyngeal carcinoma.
Journal of experimental & clinical cancer research : CR • 2018 • Vol. 37 (1)
BACKGROUND: Patient-derived xenograft (PDX) tumor model has become a new approach in identifying druggable tumor mutations, screening and evaluating personalized cancer drugs based on the mutated tar…
Chang, A; Chang, K; Chang, Y
Effects of an ethanol extract from Lactobacillus paracasei subsp. paracasei NTU 101 fermented skimmed milk on lipopolysaccharide-induced periodontal inflammation in rats.
Food & function • 2018 • Vol. 9 (9)
The increased incidence of periodontal disease in recent years has garnered considerable attention. Numerous studies have confirmed that probiotics, such as lactic acid bacteria, can ameliorate perio…
Liu, T; Pan, T; Tsai, T
Comparison of initial oral microbiomes of young adults with and without cavitated dentin caries lesions using an in situ biofilm model.
Scientific reports • 2018 • Vol. 8 (1)
Dental caries is caused by acids released from bacterial biofilms. However, the in vivo formation of initial biofilms in relation to caries remains largely unexplored. The aim of this study was to co…
Backes, C; Erol, A; Galata, V
Dental management of a patient with 22q11.2 deletion syndrome (22q11.2DS).
BMJ case reports • 2018 • Vol. 2018
22q11.2 deletion syndrome (22q11.2DS) is one of the most common microdeletion syndromes, with an incidence of approximately 1/2000-1/4000 live births; it is thought to be mainly attributable to a de …
Alharbi, A; AlQarni, M; Merdad, L
Long-term antimicrobial assessment of orthodontic brackets coated with nitrogen-doped titanium dioxide against Streptococcus mutans.
Progress in orthodontics • 2018 • Vol. 19 (1)
BACKGROUND: The antimicrobial properties of orthodontic wire and brackets with nitrogen-doped titanium dioxide (N-doped TiO2) coating have been studied in the past. However, the evaluation period had…
Babanouri, N; Roein-Peikar, M; Salehi, P
The factors that influence oral health-related quality of life in young adults.
Health and quality of life outcomes • 2018 • Vol. 16 (1)
BACKGROUND: Young adulthood is a time when subjects transform their role from a dependent child to an independent social identity. This cross-sectional study aimed to analyze the sociodemographic and…
McGrath, C; Sun, L; Wong, H
TMJ pathomorphology in patients with JIA-radiographic parameters for early diagnosis.
Head & face medicine • 2018 • Vol. 14 (1)
BACKGROUND: Juvenile idiopathic arthritis (JIA) is often accompanied by pathomorphological changes to the temporomandibular joint (TMJ). By analyzing orthodontical orthopantomograms of JIA patients t…
Holl-Wieden, A; Klenke, D; Meyer-Marcotty, P
Comparison of Significant Carotid Stenosis for Nasopharyngeal Carcinoma between Intensity-Modulated Radiotherapy and Conventional Two-Dimensional Radiotherapy.
Scientific reports • 2018 • Vol. 8 (1)
Radiotherapy (RT) serves as the most efficient treatment for nasopharyngeal carcinoma (NPC) and can cause carotid stenosis. This work compared the incidence of significant carotid stenosis between in…
Bai, S; Fan, S; Liao, W
A TGF-beta1 genetic variant at the miRNA187 binding site significantly modifies risk of HPV16-associated oropharyngeal cancer.
International journal of cancer • 2018 • Vol. 143 (6)
TGF-beta1rs1982073 polymorphism at the miRNA-187 binding site may alter TGF-beta1 expression and function, and thereby this polymorphism (genotype CT/CC) increases cancer susceptibility. HPV16 L1 ser…
Dahlstrom, K; Huang, Z; Li, G
A novel benzamide derivative protects ligature-induced alveolar bone erosion by inhibiting NFATc1-mediated osteoclastogenesis.
Toxicology and applied pharmacology • 2018 • Vol. 355
Since elevated osteoclast formation and/or activity by inhibitory responses against pathogens leads to diverse osteolytic bone diseases including periodontitis, inhibition of osteoclast differentiati…
Ihn, H; Kim, J; Kim, J