Research Papers
Interobserver agreement in dysplasia grading: toward an enhanced gold standard for clinical pathology trials.
Oral surgery, oral medicine, oral pathology and oral radiology • 2015 • Vol. 120 (4)
OBJECTIVE: Interobserver agreement in the context of oral epithelial dysplasia (OED) grading has been notoriously unreliable and can impose barriers for developing new molecular markers and diagnosti…
Abram, T; Bouquot, J; Corby, P
Early Postoperative Complications following Gracilis Free Muscle Transfer for Facial Reanimation: A Systematic Review and Pooled Data Analysis.
Journal of reconstructive microsurgery • 2015 • Vol. 31 (8)
BACKGROUND: Multiple studies have detailed promising smile restoration following gracilis free muscle transfer for facial reanimation but information detailing the potential complications is lacking.…
Garcia, R; Gosain, A; Marcus, J
Effect of bone marrow-derived stem cells and bone morphogenetic protein-2 on treatment of osteoradionecrosis in a rat model.
Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery • 2015 • Vol. 43 (8)
PURPOSE: We investigated the effect of rat mesenchymal stem cells (rMSCs) and bone morphogenetic protein-2 (BMP-2) on the osseous healing of osteoradionecrosis in the rat mandible, depending on appli…
Hwang, S; Jin, I; Kim, J
Lower CYP2C9 activity in Turkish patients with Behcet's disease compared to healthy subjects: a down-regulation due to inflammation?
European journal of clinical pharmacology • 2015 • Vol. 71 (10)
BACKGROUND: We previously reported on a Swedish patient with Behcet's disease (BD) who was an ultra-rapid metaboliser of drugs catalysed by CYP2C9. Was this extreme metabolism caused by the disease? …
Akdogan, A; Babaoglu, M; Bertilsson, L
Programmed cell removal biomarkers calreticulin and CD47 implicated in oral lichen planus.
Oral diseases • 2015 • Vol. 21 (7)
OBJECTIVES: To investigate the expression of the programmed cell removal markers, calreticulin (CRT) and CD47, known to be involved in various autoimmune diseases, in patients with oral lichen planus…
Allon, I; Hirshberg, A; Vered, H
Three-year outcomes of apicectomy (apicoectomy): Mining an insurance database.
Journal of dentistry • 2015 • Vol. 43 (10)
OBJECTIVES: The outcome of apicectomy in clinical reality is supposed to be different compared to outcomes reported from clinical trials. The objective of this study was to measure the outcome of api…
Bohm, S; Hartmann, A; Raedel, M
Additional disinfection with a modified salt solution in a root canal model.
Journal of dentistry • 2015 • Vol. 43 (10)
OBJECTIVES: The aim of this study is to investigate the disinfecting properties of a modified salt solution (MSS) and calcium hydroxide (Ca(OH)2) in a non-direct-contact ex-vivo model. METHODS: Seven…
Crielaard, W; de Soet, J; Nieman, S
Influence of non-orthodontic intervention on digit sucking and consequent anterior open bite: a preliminary study.
International dental journal • 2015 • Vol. 65 (5)
OBJECTIVES: This study aimed to assess behavioural and occlusal outcomes of non-orthodontic intervention (NOI) in a sample of children, 4-12 years of age, in Australia, in order to establish clinical…
Abbott, J; Bessho, K; Franco, C
Investigation of the potential of Raman spectroscopy for oral cancer detection in surgical margins.
Laboratory investigation; a journal of technical methods and pathology • 2015 • Vol. 95 (10)
The poor prognosis of oral cavity squamous cell carcinoma (OCSCC) patients is associated with residual tumor after surgery. Raman spectroscopy has the potential to provide an objective intra-operativ…
Baatenburg de Jong, R; Bakker Schut, T; Cals, F
Shortened dental arch and body mass index in adults 45-65 years of age: results from National Health and Nutrition Examination Survey 2005-2008.
International dental journal • 2015 • Vol. 65 (5)
OBJECTIVE: Many people have dental arches with unrestored edentulous areas posterior to natural teeth. One dental pattern is the shortened dental arch (SDA). As a result of the lack of teeth, individ…
Wiener, M; Wiener, R
MicroRNA‑214 promotes proliferation and inhibits apoptosis via targeting Bax in nasopharyngeal carcinoma cells. RETRACTED
Molecular medicine reports • 2015 • Vol. 12 (4)
The deregulation of microRNAs (miRNAs) is involved in the development and progression of various types of human malignancy. Previously, it has been suggested that miR‑214 has an oncogenic role in nas…
He, J; Tang, Y; Tian, Y
Inhibitory effects of 3-bromopyruvate in human nasopharyngeal carcinoma cells.
Oncology reports • 2015 • Vol. 34 (4)
Tumor cells depend on aerobic glycolysis for adenosine triphosphate (ATP) production, which is therefore targeted by therapeutic agents. The compound 3-bromopyruvate (3-BrPA), a strong alkylating age…
Jiang, C; Liu, H; Sun, Y
The relationships among individual and regional smoking, socioeconomic status, and oral and pharyngeal cancer survival: a mediation analysis.
Cancer medicine • 2015 • Vol. 4 (10)
Poorer survival from oral and pharyngeal cancer (OPC) has been reported for populations of lower socioeconomic status (SES), adjusting for risk factors such as patient and clinical characteristics. B…
Guo, Y; Logan, H; Marks, J
Epithelial barrier and oral bacterial infection.
Periodontology 2000 • 2015 • Vol. 69 (1)
The oral epithelial barrier separates the host from the environment and provides the first line of defense against pathogens, exogenous substances and mechanical stress. It consists of underlying con…
Groeger, S; Meyle, J
The inflammasome and danger molecule signaling: at the crossroads of inflammation and pathogen persistence in the oral cavity.
Periodontology 2000 • 2015 • Vol. 69 (1)
Inflammasomes are an oligomeric assembly of multiprotein complexes that activate the caspase-1-dependent maturation and the subsequent secretion of inflammatory interleukin-1beta and interleukin-18 c…
Lee, K; Yilmaz, O
Basic biology and role of interleukin-17 in immunity and inflammation.
Periodontology 2000 • 2015 • Vol. 69 (1)
Interleukin-17 (also known as interleukin-17A) is a key cytokine that links T-cell activation to neutrophil mobilization and activation. As such, interleukin-17 can mediate protective innate immunity…
Hajishengallis, G; Zenobia, C
Mini but mighty: microRNAs in the pathobiology of periodontal disease.
Periodontology 2000 • 2015 • Vol. 69 (1)
MicroRNAs (miRNAs) are a family of small, noncoding RNA molecules that negatively regulate protein expression either by inhibiting initiation of the translation of mRNA or by inducing the degradation…
Kebschull, M; Papapanou, P
Activation and resolution of periodontal inflammation and its systemic impact.
Periodontology 2000 • 2015 • Vol. 69 (1)
Inflammation is a highly organized event impacting upon organs, tissues and biological systems. Periodontal diseases are characterized by dysregulation or dysfunction of resolution pathways of inflam…
Hasturk, H; Kantarci, A
Nutlin-3 sensitizes nasopharyngeal carcinoma cells to cisplatin-induced cytotoxicity.
Oncology reports • 2015 • Vol. 34 (4)
The small-molecule inhibitor of p53-Mdm2 interaction, Nutlin-3, is known to be effective against cancers expressing wild-type (wt) p53. p53 mutations are rare in nasopharyngeal carcinoma (NPC), hence…
Ahmad, M; Husaini, R; Khoo, A
Parry-Romberg syndrome associated with complete agenesis of the corpus callosum: An uncommon case report.
Revue neurologique • 2015 • Vol. 171 (10)
Adali, N; Kissani, N; Zahlane, S