Research Papers

476343 papers found
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Adjuvant effects of injectable platelet-rich fibrin (i-PRF) in the non-surgical periodontal therapy: a split-mouth randomized controlled clinical trial.

Clinical oral investigations • 2025 • Vol. 29 (7)

OBJECTIVE: To assess the impact of injectable platelet-rich fibrin (i-PRF) as an adjunct to scaling and root planing (SRP) in patients with periodontitis. MATERIALS AND METHODS: Twenty-four patients,…

PMID: 40522340 PICO Pending DOI

Alves Oliveira, J; de Oliveira, G; de Oliveira Alves, R

Published: Jun 16, 2025
Beyond traditional diagnosis: aptamer-based microRNA detection for the early diagnosis of periodontitis.

Molecular biology reports • 2025 • Vol. 52 (1)

Periodontitis is a prevalent, chronic inflammatory disease linked to microbial dysbiosis and host immune response, leading to destruction of the tooth-supporting structures. Traditional diagnostic me…

PMID: 40523972 PICO Pending DOI

Ashraf, M; Butt, D; Hasan, N

Published: Jun 16, 2025
Clinical Characterization of Autoimmune Hepatic Involvement in Sjogren's Disease: A Retrospective Cohort Study in Korea.

International journal of molecular sciences • 2025 • Vol. 26 (12)

Sjogren's disease (SjD) is a systemic autoimmune disease primarily affecting the exocrine glands. Systemic manifestations, including hepatic involvement, are increasingly recognized. This study aimed…

PMID: 40565197 PICO Pending DOI PMC

Ju, J; Kim, W; Kwok, S

Published: Jun 15, 2025
Histopathological and IHC evaluation of malignant non-pigmented chromatophoroma in a savannah monitor (Varanus exanthematicus).

Acta veterinaria Hungarica • 2025 • Vol. 73 (2)

Chromatophoromas are neoplasms arising from pigment cells (chromatophores) and commonly manifest as cutaneous lesions. While brown to black melanophoromas are most prevalent in reptiles, sporadic cas…

PMID: 40323657 PICO Pending DOI

Durska, M; Gesek, M; Mikiewicz, M

Published: Jun 13, 2025
Exosomes as immunomodulators in autoimmune inflammation: implications for primary Sjogren's disease.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] • 2025 • Vol. 74 (1)

Primary Sjogren's disease (pSD) is a systemic autoimmune disorder characterized by exocrine gland dysfunction and lymphocytic infiltration, leading to dry mouth and eyes. Increasing evidence implicat…

PMID: 40512213 PICO Pending DOI

Chen, S; Gao, S; Hong, Y

Published: Jun 13, 2025
Effectiveness of Hangeshashinto in delaying grade 2 radiotherapy-induced mucositis development in patients with hypopharyngeal or laryngeal cancer: Preliminary finding of a randomized clinical trial.

Medicine • 2025 • Vol. 104 (24)

BACKGROUND: The efficacy of Hangeshashinto (TJ-14) during radiotherapy administration in patients with head and neck cancer remains unknown. We investigated the effectiveness of TJ-14 in delaying gra…

PMID: 40527845 PICO Pending DOI PMC

Kawashita, Y; Kumai, Y; Murata, M

Published: Jun 13, 2025
Hemisection versus conventional extraction as interceptive treatment in congenitally missing mandibular second premolars: a randomised controlled split-mouth trial.

European journal of orthodontics • 2025 • Vol. 47 (4)

BACKGROUND: The congenital absence of mandibular second premolars is a common anomaly requiring careful treatment planning. Conventional extraction of the primary molar often causes spontaneous space…

PMID: 40501277 PICO Pending DOI PMC

Abdul Jabbar, S; Hansen, K; Naoumova, J

Published: Jun 12, 2025
Adherence to clinical practice guidelines amongst adolescents with buccal fixed orthodontic appliances in northeast Netherlands: a cross-sectional study.

European journal of orthodontics • 2025 • Vol. 47 (4)

BACKGROUND: Adolescents undergoing orthodontic fixed appliance treatment face an increased risk of dental caries and developing white spot lesions (WSLs) due to challenges in maintaining effective or…

PMID: 40517296 PICO Pending DOI PMC

Dijkstra, P; Kuijpers-Jagtman, A; Lietmeijer, S

Published: Jun 12, 2025
Determination of optimal incisor overtreatment and molar anchorage preparation for first-premolar extraction patients treated with clear aligners.

European journal of orthodontics • 2025 • Vol. 47 (4)

OBJECTIVES: This study aimed to analyze the optimal incisor overtreatment and molar anchorage preparation in premolar-extraction cases with clear aligner therapy (CAT) and generate a formula to provi…

PMID: 40528802 PICO Pending DOI

Lai, W; Long, H; Tang, Z

Published: Jun 12, 2025
Optimizing orthodontic treatment protocol for patients with periodontitis or reduced periodontium: a systematic review and meta-analysis.

European journal of orthodontics • 2025 • Vol. 47 (4)

BACKGROUND: An increasing number of adults with periodontitis are pursuing orthodontic treatment to enhance their occlusion and aesthetics. To manage these patients effectively, it is essential to de…

PMID: 40576199 PICO Pending DOI

AlDhelaan, A; Alkhaldi, A; Alrahaimi, R

Published: Jun 12, 2025
Effects of early and later timed cervical headgear treatment on the eruption timing and pattern of permanent upper canines and molars from 7 to 18 years of age: follow-up of a randomized controlled trial.

European journal of orthodontics • 2025 • Vol. 47 (4)

BACKGROUND: Although cervical headgear (CH) is a widely studied method for the correction of Class II malocclusion, there is a lack of evidence regarding the effects of early versus later treatment t…

PMID: 40576200 PICO Pending DOI PMC

Julku, J; Kasma, K; Silvola, A

Published: Jun 12, 2025
Ionic release and electrochemical testing of 3-D printed orthodontics metallic bands made of Co-Cr and stainless-steel alloys.

European journal of orthodontics • 2025 • Vol. 47 (4)

OBJECTIVE: The aim of this study was to investigate the electrochemical characteristics and ionic release of three-dimensional (3D) printed orthodontic metallic bands made of stainless-steel (SS) and…

PMID: 40616473 PICO Pending DOI PMC

Eliades, T; Karavoltsos, S; Panayi, N

Published: Jun 12, 2025
Reporting and interpretation of subgroup analyses in orthodontic meta-analysis; a meta-epidemiological study.

European journal of orthodontics • 2025 • Vol. 47 (4)

BACKGROUND/OBJECTIVES: In systematic reviews (SRs) with a meta-analysis, a subgroup analysis can be utilised to explore heterogeneity of treatment effects across patient characteristics and assess ho…

PMID: 40677128 PICO Pending DOI

Hirst, L; Mavridis, D; Ntaga, I

Published: Jun 12, 2025
Changes in clinical crown length and the development of gingival recession associated with orthodontic treatment-induced incisor inclination changes: a retrospective cohort study.

European journal of orthodontics • 2025 • Vol. 47 (4)

BACKGROUND/OBJECTIVES: Gingival recession results from the displacement of the gingival margin apically to the cementoenamel junction. There is unclear evidence regarding the impact of orthodontic tr…

PMID: 40709396 PICO Pending DOI PMC

Alkhalidy, S; Athanasiou, A; Bin Bahar, B

Published: Jun 12, 2025
Assessing tooth mobility before and after miniscrew implantation for diagnosing root contact: a cadaveric animal study.

European journal of orthodontics • 2025 • Vol. 47 (4)

OBJECTIVE: To determine whether miniscrew-root contact can be diagnosed by assessing tooth mobility before and after miniscrew implantation. MATERIALS AND METHODS: Cadaveric pig mandibles were used, …

PMID: 40726213 PICO Pending DOI

Kusumoto, J; Miura, N; Miyawaki, S

Published: Jun 12, 2025
The impact of orthodontic-surgical treatment on female patients' temporomandibular symptoms, psychological distress, and quality of life.

European journal of orthodontics • 2025 • Vol. 47 (4)

OBJECTIVE: To analyze changes in patients' temporomandibular dysfunction (TMD) symptoms during orthodontic-surgical treatment and to investigate associations between symptoms, findings in temporomand…

PMID: 40740107 PICO Pending DOI PMC

Alanko, O; Peltomaki, T; Soukka, T

Published: Jun 12, 2025
Single-tooth resolved, whole-mouth prediction of early childhood caries via spatiotemporal variations of plaque microbiota.

Cell host & microbe • 2025 • Vol. 33 (6)

Early childhood caries (ECC) exhibits tooth specificity, highlighting the need for single-tooth-level prevention. We profiled 2,504 dental plaque microbiota samples from 89 preschoolers across two co…

PMID: 40449489 PICO Pending DOI

Huang, S; Sun, Y; Teng, F

Published: Jun 11, 2025
Pre-treatment serum apolipoprotein E: a promising prognostic indicator for nasopharyngeal carcinoma.

European journal of medical research • 2025 • Vol. 30 (1)

BACKGROUND AND PURPOSE: This preliminary study explores the prognostic value of pretreatment peripheral serum apolipoprotein E (ApoE) in patients with non-metastatic nasopharyngeal carcinoma (NPC). M…

PMID: 40495209 PICO Pending DOI PMC

Deng, S; Ding, J; He, X

Published: Jun 11, 2025
A New Classification System for Alveolar Bone Morphology around Maxillary Incisors in Adult Patients with Maxillary Protrusion.

The Chinese journal of dental research • 2025 • Vol. 28 (2)

OBJECTIVE: To develop a new alveolar bone morphology classification for maxillary incisors in patients with maxillary protrusion, and to investigate the association of alveolar morphology with skelet…

PMID: 40497765 PICO Pending DOI

Guo, R; Huang, Y; Li, W

Published: Jun 11, 2025
Evaluation of Periapical Healing Outcomes of Single-visit Non-surgical Endodontic Retreatment of Teeth with Apical Periodontitis in Patients with Type 2 Diabetes Mellitus: a Retrospective Study.

The Chinese journal of dental research • 2025 • Vol. 28 (2)

OBJECTIVE: To compare the results of non-surgical endodontic retreatment (NSER) applied in a single visit between type 2 diabetes mellitus (DM) patients with teeth with apical periodontitis (AP) and …

PMID: 40497767 PICO Pending DOI

Dogan Cankaya, T; Isik, M; Ugur Aydin, Z

Published: Jun 11, 2025
Showing 741 to 760 of 476343 papers