Research Papers

476343 papers found
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A biomimetic therapeutic nanovaccine based on dendrimer-drug conjugates coated with metal-phenolic networks for combination therapy of nasopharyngeal carcinoma: an in vitro investigation.

Journal of materials chemistry. B • 2025 • Vol. 13 (18)

Developing a minimally invasive and potent therapy for nasopharyngeal carcinoma is still challenging. In this study, we report a photothermal nanovaccine based on phenylboronic acid (PBA)-modified po…

PMID: 40241472 PICO Pending DOI

Deng, X; El-Newehy, M; Guo, Y

Published: May 07, 2025
Comparison of two surgical techniques for the extraction of mandibular horizontally impacted third molars near the mandibular canal: the displacement reduction method and the away-from-nerve method.

Clinical oral investigations • 2025 • Vol. 29 (6)

OBJECTIVES: To introduce two surgical techniques for extracting horizontally impacted wisdom teeth near the mandibular nerve canal and to assess their effectiveness. MATERIALS AND METHODS: This study…

PMID: 40329123 PICO Pending DOI

Qian, W; Wu, Y; Yang, C

Published: May 07, 2025
Efficacy of different gingival graft de-epithelialization methods: A parallel-group randomized clinical trial.

Clinical oral investigations • 2025 • Vol. 29 (6)

OBJECTIVES: The clinical outcomes of either extra-oral (eo) or intra-oral (io) de-epithelialized connective tissue graft (DE-CTG) techniques to the recipient site have not been fully elucidated yet. …

PMID: 40332625 PICO Pending DOI PMC

Avci, H; Baris, E; Caglayan, F

Published: May 07, 2025
Improving Recruitment Through Social Media and Web-Based Advertising to Evaluate the Genetic Risk and Long-Term Complications in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Community-Based Survey.

Journal of medical Internet research • 2025 • Vol. 27

BACKGROUND: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are genetically mediated, life-threatening reactions usually caused by a medication in adults. These genetic associatio…

PMID: 40334287 PICO Pending DOI PMC

Daniels, K; Marks, M; Martin-Pozo, M

Published: May 07, 2025
Assessing the influence of Katana Cleaner on the clinical performance of bulk-fill restorations in endodontically treated teeth: study protocol for a randomized clinical study.

Trials • 2025 • Vol. 26 (1)

BACKGROUND: Complete cleaning of the pulp chamber interior is a mandatory step before the restorative process. Ethanol is the most commonly used substance for cleaning the dentin surface; however, st…

PMID: 40336030 PICO Pending DOI PMC

Azevedo, J; Cardenas, A; Carvalho, C

Published: May 07, 2025
Surface Electromyographic Features for Severity Classification in Facial Palsy: Insights from a German Cohort and Implications for Future Biofeedback Use.

Sensors (Basel, Switzerland) • 2025 • Vol. 25 (9)

Facial palsy (FP) significantly impacts patients' quality of life. The accurate classification of FP severity is crucial for personalized treatment planning. Additionally, electromyographic (EMG)-bas…

PMID: 40363384 PICO Pending DOI PMC

Gorbachuk, M; Machetanz, K; Manzoor, I

Published: May 07, 2025
Comparison of clinical outcomes of polyetheretherketone and hybrid resin crowns placed on molars for over two years.

Scientific reports • 2025 • Vol. 15 (1)

This study aimed to compare the 2-year clinical outcomes of polyetheretherketone (PEEK) and hybrid resin crowns placed on molars. Patients who received PEEK (P-Cr) and hybrid resin (H-Cr) crowns at H…

PMID: 40325080 PICO Pending DOI PMC

Abekura, H; Doi, K; Kagawa, K

Published: May 05, 2025
An index system for the clinical supervision of clear aligner in extraction patients based on the Delphi method and the analytic hierarchy process.

BMC oral health • 2025 • Vol. 25 (1)

BACKGROUND: Clinical supervision of clear aligner treatment in extraction patients is essential during the long process of follow-up period. However, there is insufficient clinical guidance available…

PMID: 40325463 PICO Pending DOI PMC

Cheng, Y; Gao, J; Jin, Z

Published: May 05, 2025
The sequential association between school bullying and oral health related quality of life (OHRQoL) in Chinese children and adolescents.

BMC public health • 2025 • Vol. 25 (1)

BACKGROUND: School bullying has negative impacts on the overall health of children and adolescents, but the association between bullying and oral health-related quality of life (OHRQoL) is still uncl…

PMID: 40325468 PICO Pending DOI PMC

He, Y; Liu, S; Liu, X

Published: May 05, 2025
The effect of collagen sponge placed in the socket after surgical extraction of mandibular third molars on the incidence of alveolar osteitis: a split mouth randomized controlled trial.

Clinical oral investigations • 2025 • Vol. 29 (5)

PURPOSE: To assess the effect of collagen plug application into the alveolar socket following surgical extraction of impacted lower third molars (IL3rdM) on pain, mouth opening, and the incidence of …

PMID: 40316795 PICO Pending DOI

Abu-Mostafa, N; Moslem, F; Naif Alanazi, S

Published: May 03, 2025
Stereotactic radiosurgery for tumor-related trigeminal neuralgia: a systematic review and meta-analysis.

BMC neurology • 2025 • Vol. 25 (1)

BACKGROUND: Tumor-related trigeminal neuralgia (TRTN) accounts for approximately 6% of all facial pain syndromes. Conventional medical treatments have short-term pain relief effects in TRTN cases; ho…

PMID: 40319265 PICO Pending DOI PMC

Amjadzadeh, M; Ebrahimi, A; Habibi, M

Published: May 03, 2025
Effect of periodontal therapy on lung function: a twelve-month follow-up intervention study.

Respiratory research • 2025 • Vol. 26 (1)

BACKGROUND: Evidence suggest an inflammatory link between respiratory health and periodontitis. This study aims to evaluate the impact of periodontal therapy on lung function. METHODS: Sixty-two neve…

PMID: 40319277 PICO Pending DOI PMC

Bertelsen, R; Bunaes, D; Heinrich, J

Published: May 03, 2025
Association Between Periodontal Pathogens and Inflammation in Patients with Acute Coronary Syndromes.

International journal of molecular sciences • 2025 • Vol. 26 (9)

(1) The link between periodontal disease (PD) and acute coronary syndromes (ACSs) is predominantly attributed to the atherosclerotic process, mediated by systemic inflammation. However, the correlati…

PMID: 40362598 PICO Pending DOI PMC

Benedek, I; Benedek, T; Blindu, E

Published: May 03, 2025
A Distinguishable Peripheral Blood and Conjunctival Transcriptome and Gut Microbiome in Sjogren's Disease: A Pilot Study.

Eye & contact lens • 2025 • Vol. 51 (7)

OBJECTIVE: To create a comprehensive multi-tissue molecular atlas of Sjogren's disease by using unbiased RNA sequencing to identify differentially expressed genes (DEGs) in peripheral blood and conju…

PMID: 40314468 PICO Pending DOI PMC

Chen, C; Doan, T; Gebreegziabher, E

Published: May 02, 2025
Improving oral health outcomes through community nursing.

British journal of community nursing • 2025 • Vol. 30 (5)

This article highlights the crucial role of community nurses in promoting and maintaining oral health in patients, which is integral to their overall wellbeing. Oral health is directly linked to vari…

PMID: 40315165 PICO Pending DOI

Palmer, S

Published: May 02, 2025
Exploring the unexpected: sensorineural hearing loss and vertigo as a complication of mumps.

BMJ case reports • 2025 • Vol. 18 (5)

Mumps, an acute viral infection characterised by parotid gland swelling, can lead to sensorineural hearing loss (SNHL) and vestibular symptoms. This report discusses a man in his early 30s who develo…

PMID: 40316282 PICO Pending DOI

Akthar, H; Barman, B; Kallyadan Veetil, A

Published: May 02, 2025
KLF7-regulated ITGA2 as a therapeutic target for inhibiting oral cancer stem cells.

Cell death & disease • 2025 • Vol. 16 (1)

Cancer stem cells (CSCs) play crucial roles in tumor metastasis, therapy resistance, and immune evasion. Identifying and understanding the factors that regulate the stemness of tumor cells presents p…

PMID: 40316546 PICO Pending DOI PMC

Cui, R; He, Y; Li, C

Published: May 02, 2025
Evaluating the efficacy of Chenopodium murale plant extract in inhibiting Streptococcus mutans and reducing dental caries risk.

Scientific reports • 2025 • Vol. 15 (1)

The relationship between Streptococcus mutans and dental caries has been a key focus of research due to the widespread prevalence of caries in humans. In this study, we have investigated the antimicr…

PMID: 40316577 PICO Pending DOI PMC

Ahmad, A; Bashir, S; Bin Jardan, Y

Published: May 02, 2025
Knowledge level of diagnostic procedures and risk factors for oral cancer among oral healthcare providers in Germany.

BMC oral health • 2025 • Vol. 25 (1)

BACKGROUND: Oral cancer is an underestimated and growing public health problem. The majority of cases are diagnosed at a late stage, even though oral cancer can be detected early by routine visual an…

PMID: 40317003 PICO Pending DOI PMC

Baumann, E; Dempfle, A; Felgendreff, L

Published: May 02, 2025
Access to oral healthcare for children during the COVID-19 pandemic: a mixed-methods study in the Aegean region of Turkiye.

BMC oral health • 2025 • Vol. 25 (1)

BACKGROUND: The COVID-19 pandemic significantly disrupted healthcare systems, particularly affecting vulnerable populations such as children and individuals with special needs, causing delays and red…

PMID: 40317032 PICO Pending DOI PMC

Arabulan, S; Ocek, Z; Oncag, R

Published: May 02, 2025
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