Research Papers

476343 papers found
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Oral Selective Estrogen Receptor Degraders (SERDs) in Breast Cancer: Advances, Challenges, and Current Status.

Drug design, development and therapy • 2022 • Vol. 16

Several endocrine therapies are currently available for the treatment of estrogen receptor (ER) positive breast cancer, but the clinical benefit of these agents is limited by endocrine therapy drug r…

PMID: 36081610 PICO Pending DOI PMC

Downton, T; Jeselsohn, R; Lim, E

Published: Jan 01, 2022
Alterations in Oral Microbiota of Differentiated Thyroid Carcinoma Patients With Xerostomia After Radioiodine Therapy.

Frontiers in endocrinology • 2022 • Vol. 13

BACKGROUND AND AIMS: Oral xerostomia remains one of the most common complications of differentiated thyroid carcinoma patients (DTC) after radioiodine therapy (RAI). Environmental factors in the etio…

PMID: 36093087 PICO Pending DOI PMC

Chen, H; Feng, J; Guo, X

Published: Jan 01, 2022
Pyroptosis in periodontitis: From the intricate interaction with apoptosis, NETosis, and necroptosis to the therapeutic prospects.

Frontiers in cellular and infection microbiology • 2022 • Vol. 12

Periodontitis is highly prevalent worldwide. It is characterized by periodontal attachment and alveolar bone destruction, which not only leads to tooth loss but also results in the exacerbation of sy…

PMID: 36093182 PICO Pending DOI PMC

Ai, D; Qin, H; Song, J

Published: Jan 01, 2022
Case report and analysis: Behcet's disease with lower extremity vein thrombosis and pseudoaneurysm.

Frontiers in immunology • 2022 • Vol. 13

BACKGROUND: Behcet's disease (BD) is a unique autoimmune chronic systemic vasculitis that affects veins and arteries of all sizes. BD can lead to recurrent vascular events, especially venous thrombos…

PMID: 36105822 PICO Pending DOI PMC

Fang, Z; Liao, L; Lin, J

Published: Jan 01, 2022
Rare Location of a Dermoid Cyst in the Parotid Gland: A Case Report.

Prague medical report • 2022 • Vol. 123 (3)

Dermoid cyst of the parotid gland is a lesion composed of benign tissues of ectodermal and mesodermal origin. Although a dermoid cyst can be encountered across nearly all sites of the body, its locat…

PMID: 36107448 PICO Pending DOI

Babal, P; Cierna, Z; Czako, L

Published: Jan 01, 2022
Transcriptional analysis highlights three distinct immune profiles of high-risk oral epithelial dysplasia.

Frontiers in immunology • 2022 • Vol. 13

Oral potentially malignant disorders (OPMD) are precursors of oral squamous cell carcinoma (OSCC), and the presence of oral epithelial dysplasia (OED) in OPMD confers an increased risk of malignant t…

PMID: 36119104 PICO Pending DOI PMC

Ariffin, H; Cheong, S; Gan, C

Published: Jan 01, 2022
Dental health in patients with and without HPV-positive oropharyngeal and tongue cancer.

PLoS One • 2022 • Vol. 17 (9)

BACKGROUND: Human papilloma virus is associated with oral and oropharyngeal cancer. Our aim was to examine oral health in patients with oropharyngeal (OPSCC) and oral tongue cancer (OTSCC), expecting…

PMID: 36137133 PICO Pending DOI PMC

Jouhi, L; Makitie, A; Meurman, J

Published: Jan 01, 2022
Identification of Key Genes and Pathways Associated with Oxidative Stress in Periodontitis.

Oxidative medicine and cellular longevity • 2022 • Vol. 2022

METHODS: The differentially expressed genes (DEGs) were identified using periodontitis-related microarray from the GEO database, and OS-genes were extracted from GeneCards database. The intersection …

PMID: 36148415 PICO Pending DOI PMC

Bian, X; Chou, J; Liu, H

Published: Jan 01, 2022
A Unique Case of Aggressive Central Giant Cell Granuloma in a 10-Year-Old Boy With 16p13.11 Microdeletion Syndrome.

Journal of investigative medicine high impact case reports • 2022 • Vol. 10

Central giant cell granuloma (CGCG) is a rare disease characterized by sporadic, benign, intraosseous mandibular lesions of unknown etiology. Histologically, these lesions are indistinguishable from …

PMID: 36154495 PICO Pending DOI PMC

Hammoudeh, J; Kim, M; Kondra, K

Published: Jan 01, 2022
Bioinformatic Data Mining for Candidate Drugs Affecting Risk of Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) in Cancer Patients.

Disease markers • 2022 • Vol. 2022

BACKGROUND: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) leads to significant morbidity. Other coadministered drugs may modulate the risk for BRONJ. The present study aimed to leverage bio…

PMID: 36157219 PICO Pending DOI PMC

Jing, Y; Kong, P; Sun, Y

Published: Jan 01, 2022
Global trends in research on oxidative stress associated with periodontitis from 1987 to 2022: A bibliometric analysis.

Frontiers in immunology • 2022 • Vol. 13

BACKGROUND: Oxidative stress has been implicated in many chronic inflammatory diseases, including periodontitis. To date, however, only a few bibliometric analyses have systematically studied this fi…

PMID: 36159848 PICO Pending DOI PMC

Hou, Y; Li, Q; Liu, X

Published: Jan 01, 2022
Post-trauma complex orthodontic approach: the impact of psychological issues of bullying on treatment decision.

Dental press journal of orthodontics • 2022 • Vol. 27 (4)

OBJECTIVE: This article aims to discuss the multidisciplinary approach required in the treatment of cases of impaction and ankylosis of permanent teeth, associated with a history of trauma, consideri…

PMID: 36169498 PICO Pending DOI PMC

Carvalho, F; Feu, D

Published: Jan 01, 2022
Saliva sample for detection of SARS-CoV-2: A possible alternative for mass testing.

PLoS One • 2022 • Vol. 17 (9)

Molecular diagnostic testing has played a critical role in the global response to the novel Coronavirus disease (COVID-19) pandemic, since its first outbreak in late 2019. At the inception of the COV…

PMID: 36170269 PICO Pending DOI PMC

Abdullah, M; Abiola, A; Akase, I

Published: Jan 01, 2022
Etiology and pattern of maxillofacial trauma.

PLoS One • 2022 • Vol. 17 (9)

INTRODUCTION: Maxillofacial trauma can be limited to superficial lacerations, abrasions, and facial bone fractures. The objective of this study was to determine the etiology, pattern, and predictors …

PMID: 36174089 PICO Pending DOI PMC

Banouri, S; Khan, T; Khan, Z

Published: Jan 01, 2022
Periodontitis-related salivary microbiota aggravates Alzheimer's disease via gut-brain axis crosstalk.

Gut microbes • 2022 • Vol. 14 (1)

The oral cavity is the initial chamber of digestive tract; the saliva swallowed daily contains an estimated 1.5 x 10(12) oral bacteria. Increasing evidence indicates that periodontal pathogens and su…

PMID: 36175166 PICO Pending DOI PMC

Huang, Y; Li, Y; Lu, J

Published: Jan 01, 2022
Context Aware Convolutional Neural Network for Children Caries Diagnosis on Dental Panoramic Radiographs.

Computational and mathematical methods in medicine • 2022 • Vol. 2022

The objective of this study is to improve traditional convolutional neural networks for more accurate children dental caries diagnosis on panoramic radiographs. A context aware convolutional neural n…

PMID: 36188109 PICO Pending DOI PMC

Liu, Y; Sun, J; Yin, Q

Published: Jan 01, 2022
Patients with obstructive sleep apnea can favor the predisposing factors of periodontitis by the presence of P. melaninogenica and C. albicans, increasing the severity of the periodontal disease.

Frontiers in cellular and infection microbiology • 2022 • Vol. 12

OBJECTIVE: The aim of this study was to analyze the cultivable oral microbiota of patients with obstructive sleep apnea (OSA) and its association with the periodontal condition. METHODS: The epidemio…

PMID: 36189359 PICO Pending DOI PMC

Arango-Jimenez, N; Cortes, M; Cuervo-Jimenez, H

Published: Jan 01, 2022
Artificial Neural Network Assisted Cancer Risk Prediction of Oral Precancerous Lesions. RETRACTED

BioMed research international • 2022 • Vol. 2022

The incidence of oral cancer is still increasing. It has become very common in patients with malignant tumors, which has forced medical personnel to continuously explore its treatment methods. What k…

PMID: 36193309 PICO Pending DOI PMC

Chen, W; Jin, Y; Sun, X

Published: Jan 01, 2022
Degreasing and bleaching bones using light sources as a tool to increase the safety of teaching osteology at the University of Veterinary Sciences Brno.

PeerJ • 2022 • Vol. 10

The key part of creating bone material for teaching is degreasing and whitening it. However, the substances used are often dangerous and toxic. We tested and compared safer methods based on two physi…

PMID: 36193429 PICO Pending DOI PMC

Horak, O; Paral, V; Pyszko, M

Published: Jan 01, 2022
Alterations of m6A RNA methylation regulators contribute to autophagy and immune infiltration in primary Sjogren's syndrome.

Frontiers in immunology • 2022 • Vol. 13

N6-methyladenosine (m6A) RNA modification is a new epigenetic regulation mechanism on eukaryotic mRNA. Few autoimmune diseases focused on the role of m6A in their pathogenies, and m6A modulation in t…

PMID: 36203590 PICO Pending DOI PMC

Cheng, L; Huang, Y; Li, H

Published: Jan 01, 2022
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