Research Papers
METTL3-mediated m6A modification of SLC7A11 enhances nasopharyngeal carcinoma radioresistance by inhibiting ferroptosis.
International journal of biological sciences • 2025 • Vol. 21 (4)
Radiotherapy is the primary treatment for nasopharyngeal carcinoma (NPC); nonetheless, radioresistance remains the leading cause of localized recurrence. Our study demonstrates a significant increase…
Dai, Z; Liao, K; Lin, B
Evaluation of the personality traits in subjects in need of orthodontic treatment using the Big Five model: A cross-sectional questionnaire-based study.
Dental and medical problems • 2025 • Vol. 62 (1)
BACKGROUND: Malocclusion can be regarded as a civilizational disease, and its psychological implications remain a subject of debate. OBJECTIVES: The aim of the study was to examine different personal…
Bhayya, D; Kubavat, A; Shyagali, T
Comparative evaluation of mechanical effects of two designs of immediately placed customized root-analogue zirconia implants in the maxillary and mandibular posterior regions: A finite element analysis.
Dental and medical problems • 2025 • Vol. 62 (1)
BACKGROUND: Customized root-analogue implants (RAIs) with a press-fit design, inserted immediately after tooth extraction, have garnered attention from the researchers and dentists due to their abili…
Alam, M; Divakar, S; Jain, P
Comparative analysis of acute and chronic painful temporomandibular disorders: Insights into pain, behavioral, and psychosocial features.
PLoS One • 2025 • Vol. 20 (2)
OBJECTIVE: The scarcity of literature necessitates further research to differentiate between acute and chronic painful temporomandibular disorders (TMDs). This study compared pain characteristics, or…
Jo, J; Kim, S; Lee, B
Microbial dysbiosis in periodontitis and peri-implantitis: pathogenesis, immune responses, and therapeutic.
Frontiers in cellular and infection microbiology • 2025 • Vol. 15
The oral microbiome comprises over 700 distinct species, forming complex biofilms essential for maintaining oral and systemic health. When the microbial homeostasis in the periodontium is disrupted, …
Cui, Z; Gao, W; Wang, P
Weaving oral health provider perspectives to guide future dental therapy advocacy and implementation efforts.
Frontiers in public health • 2025 • Vol. 13
INTRODUCTION: American Indian and Alaska Native (AI/AN) communities in the United States (U.S.) face greater oral healthcare inequities than other groups in the country. A solution to improving oral …
Llaneza, A; Seward, J; Stone, K
Vortioxetine versus SSRI/SNRI with Pregabalin Augmentation in Treatment-Resistant Burning Mouth Syndrome: A Prospective Clinical Trial.
Current neuropharmacology • 2025 • Vol. 23 (7)
OBJECTIVES: The treatment of Burning Mouth Syndrome (BMS) represents a challenge in tailoring appropriate medication for individual patients. The augmentation of pregabalin to conventional treatment …
Adamo, D; Albert, U; Aria, M
[The use of modern wound dressings based for the treatment of palatal defects in patients with cleft lip and palate].
Stomatologiia • 2025 • Vol. 104 (1)
The favorable course of postoperative healing is a crucial stage in surgical treatment and a significant factor in achieving successful outcomes. The rehabilitation of patients with cleft lip and pal…
Chkadua, T; Egiazaryan, A; Medusheva, E
[Improving the symptomatic diagnosis of mesial occlusion - a stage of differential diagnostics of dentofacial anomalies].
Stomatologiia • 2025 • Vol. 104 (1)
THE AIM OF THE STUDY: Was to improve the quality of symptomatic diagnostics of mesial occlusion. MATERIALS AND METHODS: The object of our epidemiological study was 2842 schoolchildren aged 6 to 18 ye…
Abakarov, S; Abakarova, A; Basov, A
Is prevalence of dental anomalies site-specific in cleft lip and palate patients? A systematic review and meta-analysis.
Dental and medical problems • 2025 • Vol. 62 (1)
The prevalence of cleft lip in conjunction with cleft palate is twice that of cleft lip or palate alone. Dental abnormalities are more frequent in patients with cleft lip and palate (CLP) than in non…
Batra, P; Gupta, A; Lalfakawmi, S
The Use of Front Plateau in the Treatment of Temporomandibular Disorders: A Case Series and Literature Review.
Prague medical report • 2025 • Vol. 126 (1)
Temporomandibular disorders (TMDs) are conditions with multifactorial etiology and complex treatment. Among the non-invasive therapeutic possibilities for these conditions is the Front Plateau, a par…
Colombecky, M; de Almeida E Silva, L; de Oliveira, S
Genetic associations of Neat1 polymorphisms with clinicopathologic characteristics of tongue cancer.
International journal of medical sciences • 2025 • Vol. 22 (5)
One of the most common malignant tumors of the head and neck region is tongue cancer. Long noncoding RNAs (lncRNAs) called nuclear enriched abundant transcript 1 (Neat1) are linked to tumor growth, s…
Chen, K; Chen, M; Chuang, C
Comparison of fracture resistance between immediate and delayed composite restorations with or without fiber after root canal treatment: a field-emission-gun scanning electron microscope study.
PeerJ • 2025 • Vol. 13
BACKGROUND: This study aimed to evaluate the fracture resistance of immediate and delayed restorations after root canal treatment (RCT). METHODS: Sixty human intact premolar teeth were used. Teeth we…
Akbal Dincer, G; Donmez, N; Kaynar, Z
Unraveling the Complex Nexus of Macrophage Metabolism, Periodontitis, and Associated Comorbidities.
Journal of innate immunity • 2025 • Vol. 17 (1)
BACKGROUND: Periodontitis is recognized as one of the most prevalent oral dysbiotic inflammatory diseases, ultimately leading to the irreversible destruction of periodontal tissues. Macrophages play …
Liu, Y; Liu, Z; Yu, T
Minocycline-Loaded Titanium Dioxide Nanoparticles for Augmented Synergistic Periodontal Sonodynamic Chemotherapy.
International journal of nanomedicine • 2025 • Vol. 20
BACKGROUND: The current clinical treatment of periodontitis usually involves mechanical removal of pathogenic bacteria through ultrasonic scaling and root planing, supplemented with antibacterial med…
Chen, Y; Huang, S; Li, X
Diagnostic Accuracy and Risk of Malignancy in Salivary Lesions Reclassified Using the Revised Milan System: A Single-Institution Retrospective Analysis.
Acta cytologica • 2025 • Vol. 69 (3)
INTRODUCTION: Salivary gland tumours represent 3% of head and neck neoplasms. Fine needle aspiration cytology (FNAC) is widely used for pre-operative diagnosis, but its accuracy varies due to the div…
Agrawal, M; Ahluwalia, C; Ahuja, S
Multimodal management of a persistent labial hemangioma: a case report.
General dentistry • 2025 • Vol. 73 (1)
Hemangiomas are benign vascular tumors that are relatively unusual in the oral cavity. The management of labial hemangiomas may be challenging for functional and esthetic reasons. In the present case…
Correia-Neto, I; Faustino, I; Fernandes, D
Coronal microleakage of endodontic access restorations in zirconia crowns.
General dentistry • 2025 • Vol. 73 (1)
Inadequate marginal sealing in endodontically treated teeth can lead to microleakage and treatment failure. The purpose of this in vitro study was to quantify and compare the quality of the marginal …
Adcook, R; Avillo, A; Burns, K
Thermal effects caused by the association of hybrid light and incorporation of titanium dioxide into 37% carbamide peroxide for dental bleaching.
General dentistry • 2025 • Vol. 73 (1)
This study monitored the thermal changes in the pulp chamber and on the buccal surface of teeth during in-office bleaching with 37% carbamide peroxide (CP) either with or without the incorporation of…
Basting, R; Bronze-Uhle, E; Carlos, N
Validation of oblique line contrast (W-index) for osteoporosis risk screening in panoramic radiographs using peripheral dual-energy X-ray absorptiometry.
General dentistry • 2025 • Vol. 73 (1)
The objective of this study was to validate the usefulness of the W-index (WI) for screening patients at risk of osteoporosis by correlating the WI results with those obtained from peripheral dual-en…
Arita, E; Brandao Junior, V; Lourenco, A