Evidence Gaps Analysis
3688 outcomes from 214 review series
CD012213
Current Version: CD012213.PUB2
Current Evidence Gaps 21 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| patients reporting halitosis | brushing + cetylpyridium mouthwash | brushing | Dentist-reported OLT score | Low | Not specified |
| patients reporting halitosis | 0.3% triclosan toothpaste | control toothpaste | Patient-reported OLT score | No Evidence Yet | N/A |
| patients reporting halitosis | 0.3% triclosan toothpaste | control toothpaste | Adverse events | No Evidence Yet | N/A |
| patients reporting halitosis | 0.6% eucalyptus chewing gum | placebo chewing gum | Patient-reported OLT score | No Evidence Yet | N/A |
| patients reporting halitosis | 0.6% eucalyptus chewing gum | placebo chewing gum | Adverse events | No Evidence Yet | N/A |
| patients reporting halitosis | 1000 mg champignon | placebo | Adverse events | No Evidence Yet | N/A |
| patients reporting halitosis | 1000 mg champignon | placebo | Dentist-reported OLT score | No Evidence Yet | N/A |
| patients reporting halitosis | brushing + cetylpyridium mouthwash | brushing | Patient-reported OLT score | No Evidence Yet | N/A |
| patients reporting halitosis | brushing + cetylpyridium mouthwash | brushing | Adverse events | No Evidence Yet | N/A |
| patients reporting halitosis | hinokitiol gel | placebo gel | Patient-reported OLT score | No Evidence Yet | N/A |
| patients reporting halitosis | hinokitiol gel | placebo gel | Adverse events | No Evidence Yet | N/A |
| patients reporting halitosis | mechanical tongue cleaning | no tongue cleaning | Patient-reported OLT score | No Evidence Yet | N/A |
| patients reporting halitosis | mechanical tongue cleaning | no tongue cleaning | Adverse events | No Evidence Yet | N/A |
| patients reporting halitosis | mouthwash containing chlorhexidine and zinc acetate | placebo mouthwash | Adverse events | No Evidence Yet | N/A |
| patients reporting halitosis | mouthwash containing chlorhexidine and zinc acetate | placebo mouthwash | Patient-reported OLT score | No Evidence Yet | N/A |
| patients reporting halitosis | 0.3% triclosan toothpaste | control toothpaste | Dentist-reported breath odour score | Very Low | Not specified |
| patients reporting halitosis | 0.6% eucalyptus chewing gum | placebo chewing gum | Dentist-reported OLT score | Very Low | Not specified |
| patients reporting halitosis | 1000 mg champignon | placebo | Patient-reported VAS | Very Low | Not specified |
| patients reporting halitosis | hinokitiol gel | placebo gel | Dentist-reported OLT score | Very Low | Not specified |
| patients reporting halitosis | mechanical tongue cleaning | no tongue cleaning | Dentist-reported OLT score | Very Low | Not specified |
| patients reporting halitosis | mouthwash containing chlorhexidine and zinc acetate | placebo mouthwash | Dentist-reported OLT score | Very Low | Not specified |
CD012256
Current Version: CD012256.PUB2
Current Evidence Gaps 18 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| Completely edentulous people | Alginate | Silicone | Participant-reported oral health-related quality of life (OHIP-EDENT) | Low | Not specified |
| People requiring removable partial dentures | Altered cast | One-piece cast | Participant-reported quality of the denture: general satisfaction | Low | Not specified |
| Completely edentulous people | Alginate | Silicone | Participantâreported quality of the denture Followâup: two weeks | No Evidence Yet | N/A |
| Completely edentulous people | Alginate | Silicone | Number of border adjustments and sore spots after insertion of denture Followâup: two weeks | No Evidence Yet | N/A |
| Completely edentulous people | Single stage with alginate | Two stage-two step elastomer | Number of border adjustments and sore spots after insertion of denture | No Evidence Yet | N/A |
| Completely edentulous people | Single-stage with alginate | Two step-two stage with ZoE | Number of border adjustments and sore spots after insertion of denture | No Evidence Yet | N/A |
| Completely edentulous people | Wax | Polysulfide rubber | Participantâreported oral healthârelated quality of life (OHIPâEDENT) | No Evidence Yet | N/A |
| Completely edentulous people | Wax | Polysulfide rubber | Participantâreported quality of the denture | No Evidence Yet | N/A |
| People requiring removable partial dentures | Altered cast | One-piece cast | Participantâreported oral healthârelated quality of life | No Evidence Yet | N/A |
| Completely edentulous people | Biofunctional prosthetic system (Accu-dent System) | Traditional technique | Number of border adjustments and sore spots after insertion of denture | Very Low | Not specified |
| Completely edentulous people | Biofunctional prosthetic system (Accu-dent System) | Traditional technique | Participant-reported quality of the denture - denture satisfaction | Very Low | Not specified |
| Completely edentulous people | Biofunctional prosthetic system (Accu-dent System) | Traditional technique | Participant-reported oral health-related quality of life (OHIP-EDENT) | Very Low | Not specified |
| Completely edentulous people | Single stage with alginate | Two stage-two step elastomer | Participant-reported oral health-related quality of life (OHIP-EDENT) | Very Low | Not specified |
| Completely edentulous people | Single stage with alginate | Two stage-two step elastomer | Participant-reported quality of the denture - general satisfaction | Very Low | Not specified |
| Completely edentulous people | Single-stage with alginate | Two step-two stage with ZoE | Participant-reported oral health-related quality of life (OHIP-EDENT) | Very Low | Not specified |
| Completely edentulous people | Single-stage with alginate | Two step-two stage with ZoE | Participant-reported quality of the denture: general satisfaction | Very Low | Not specified |
| Completely edentulous people | Wax | Polysulfide rubber | Number of border adjustments and sore spots after insertion of denture | Very Low | Not specified |
| People requiring removable partial dentures | Altered cast | One-piece cast | Number of intaglio adjustments | Very Low | Not specified |
CD012293
Current Version: CD012293.PUB2
Current Evidence Gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| People on continuous oral anticoagulant treatment | Antifibrinolytic therapy (tranexamic acid (TXA) OR epsilon aminocaproic acid (EACA)) | Placebo | Postoperative bleedings requiring intervention (placebo control, 7 days follow-up) | Moderate | Not specified |
| People on continuous oral anticoagulant treatment | Antifibrinolytic therapy (tranexamic acid (TXA) OR epsilon aminocaproic acid (EACA)) | Standard Care | Postoperative bleedings requiring intervention (standard care control, 7 days follow-up) | Moderate | Not specified |
| People on continuous oral anticoagulant treatment | Antifibrinolytic therapy (tranexamic acid (TXA) OR epsilon aminocaproic acid (EACA)) | Placebo | Side effects or other adverse events requiring withdrawal (placebo control, 7 days follow-up) | Moderate | Not specified |
CD012416
Current Version: CD012416.PUB3
| 1 older version
Current Evidence Gaps 4 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| older adults | professional oral care | usual oral care | Incidence of NHAP | Low | Not specified |
| older adults | professional oral care | usual oral care | Mortality (pneumonia-associated) | Low | Not specified |
| older adults | professional oral care | usual oral care | Adverse effects of interventions | No Evidence Yet | N/A |
| older adults | professional oral care | usual oral care | Mortality (all-cause) | Very Low | Not specified |
Previous Versions
CD012416.PUB2
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| elderly people | professional oral care | usual oral care | Mortality (pneumonia-associated) | Low | - |
| elderly people | professional oral care | usual oral care | Incidence rate of NHAP | Low | - |
| elderly people | professional oral care | usual oral care | Incidence proportion (cumulative incidence) of NHAP | Low | - |
| elderly people | oral care | no oral care | Adverse effects of interventions | No Evidence Yet | - |
| elderly people | oral care | no oral care | Incidence rate of NHAP | No Evidence Yet | - |
| elderly people | oral care | no oral care | Incidence proportion of NHAP | No Evidence Yet | - |
| elderly people | oral care | no oral care | Mortality (pneumonia-associated) | No Evidence Yet | - |
| elderly people | oral care | no oral care | Mortality (all-cause) | No Evidence Yet | - |
| elderly people | professional oral care | usual oral care | Mortality (all-cause) | Very Low | - |
CD012432
Current Version: CD012432.PUB3
| 1 older version
Current Evidence Gaps 11 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| People on antiresorptive treatment | Subperiosteal wound closure | Epiperiosteal wound closure after tooth extraction | MRONJ after tooth extraction | Low | Not specified |
| People with MRONJ | Teriparatide 20 μg daily | Placebo | Healing of MRONJ | Low | Not specified |
| People at risk of MRONJ | Dental examinations at three-month intervals and preventive treatments | Standard care | MRONJ (incidence proportion) | Very Low | Not specified |
| People treated with IV bisphosphonates who need dental extractions | Dental extraction protocol with PRGF | Standard dental extraction protocol without PRGF | MRONJ (incidence proportion) | Very Low | Not specified |
| People with MRONJ | Autofluorescence-guided bone surgery | Tetracycline fluorescence-guided bone surgery | Healing of MRONJ | Very Low | Not specified |
| People with MRONJ | Autofluorescence-guided surgery | Conventional surgery | Healing of MRONJ | Very Low | Not specified |
| People with MRONJ | Bone morphogenetic protein-2 together with platelet-rich fibrin | Platelet-rich fibrin alone | Healing of MRONJ | Very Low | Not specified |
| People with MRONJ | Concentrated growth factor and primary wound closure | Primary wound closure only | Healing of MRONJ | Very Low | Not specified |
| People with MRONJ | HBO as an adjunct to conventional therapy | Conventional therapy | Healing of MRONJ | Very Low | Not specified |
| People with MRONJ | Platelet-rich fibrin after bone surgery | Surgery alone | Healing of MRONJ | Very Low | Not specified |
| People with MRONJ | Teriparatide 56.5 μg weekly | Teriparatide 20 μg daily | Healing of MRONJ | Very Low | Not specified |
Previous Versions
CD012432.PUB2
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| prophylaxis of MRONJ | dental examinations at three-month intervals and preventive treatments | standard care | MRONJ (incidence proportion) | Low | - |
| people treated with IV bisphosphonates who need dental extractions | a dental extraction protocol with PRGF | a standard dental extraction protocol without PRGF | MRONJ (incidence proportion) | Very Low | - |
| treatment of MRONJ | autofluorescence-guided bone surgery | tetracycline fluorescence-guided bone surgery | Healing of MRONJ | Very Low | - |
| treatment of MRONJ | hyperbaric oxygen therapy as an adjunct to conventional therapy | conventional therapy | Healing of MRONJ | Very Low | - |
CD012568
Current Version: CD012568.PUB2
Current Evidence Gaps 70 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| Adults with periodontitis (aggressive) | Clindamycin + SRP | Doxycycline + SRP | Antimicrobial resistance | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | Metronidazole + SRP | Percentage of BOP | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | Metronidazole + SRP | Antimicrobial resistance | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | Metronidazole + SRP | Adverse events | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | SRP | Antimicrobial resistance | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | Doxycycline + SRP | Patient-reported quality of life changes | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | Metronidazole + SRP | Patient-reported quality of life changes | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | SRP | Patient-reported quality of life changes | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | SRP | Percentage of closed pockets | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | SRP | Adverse events | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | Doxycycline + SRP | Probing pocket depth | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | SRP | Percentage of BOP | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | Doxycycline + SRP | Percentage of BOP | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | Metronidazole + SRP | Percentage of closed pockets | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | Doxycycline + SRP | Adverse events | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Doxycycline + SRP | Metronidazole + SRP | Percentage of BOP | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Doxycycline + SRP | SRP | Antimicrobial resistance | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Doxycycline + SRP | SRP | Adverse events | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Doxycycline + SRP | SRP | Patient-reported quality of life changes | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Doxycycline + SRP | Metronidazole + SRP | Patient-reported quality of life changes | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Doxycycline + SRP | Metronidazole + SRP | Adverse events | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Doxycycline + SRP | Metronidazole + SRP | Antimicrobial resistance | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Doxycycline + SRP | SRP | Percentage of BOP | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Doxycycline + SRP | Metronidazole + SRP | Percentage of closed pockets | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Doxycycline + SRP | SRP | Percentage of closed pockets | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Tetracycline + SRP | SRP | Percentage of closed pockets | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Tetracycline + SRP | SRP | Probing pocket depth | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Tetracycline + SRP | SRP | Percentage of BOP | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Tetracycline + SRP | SRP | Antimicrobial resistance | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Tetracycline + SRP | SRP | Adverse events | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Tetracycline + SRP | SRP | Patient-reported quality of life changes | No Evidence Yet | N/A |
| Adults with periodontitis (chronic) | Amoxicillin + clavulanate + SRP | SRP | Antimicrobial resistance | No Evidence Yet | N/A |
| Adults with periodontitis (chronic) | Amoxicillin + clavulanate + SRP | SRP | Patient-reported quality of life changes | No Evidence Yet | N/A |
| Adults with periodontitis (chronic) | Amoxicillin + clavulanate + SRP | SRP | Percentage of closed pockets | No Evidence Yet | N/A |
| Adults with periodontitis (chronic/aggressive) | Amoxicillin + metronidazole + SRP | SRP | Patient-reported quality of life changes | No Evidence Yet | N/A |
| Adults with periodontitis (chronic/aggressive) | Amoxicillin + metronidazole + SRP | SRP | Antimicrobial resistance | No Evidence Yet | N/A |
| Adults with periodontitis (chronic/aggressive) | Azithromycin + SRP | SRP | Antimicrobial resistance | No Evidence Yet | N/A |
| Adults with periodontitis (chronic/aggressive) | Azithromycin + SRP | SRP | Patient-reported quality of life changes | No Evidence Yet | N/A |
| Adults with periodontitis (chronic/aggressive) | Metronidazole + SRP | SRP | Patient-reported quality of life changes | No Evidence Yet | N/A |
| Adults with periodontitis (chronic/aggressive) | Metronidazole + SRP | SRP | Antimicrobial resistance | No Evidence Yet | N/A |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | SRP | CAL | Very Low | Not specified |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | Doxycycline + SRP | Percentage of closed pockets | Very Low | Not specified |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | Metronidazole + SRP | Probing pocket depth | Very Low | Not specified |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | Metronidazole + SRP | CAL | Very Low | Not specified |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | SRP | Probing pocket depth | Very Low | Not specified |
| Adults with periodontitis (aggressive) | Clindamycin + SRP | Doxycycline + SRP | CAL | Very Low | Not specified |
| Adults with periodontitis (aggressive) | Doxycycline + SRP | Metronidazole + SRP | CAL | Very Low | Not specified |
| Adults with periodontitis (aggressive) | Doxycycline + SRP | SRP | Probing pocket depth | Very Low | Not specified |
| Adults with periodontitis (aggressive) | Doxycycline + SRP | SRP | CAL | Very Low | Not specified |
| Adults with periodontitis (aggressive) | Doxycycline + SRP | Metronidazole + SRP | Probing pocket depth | Very Low | Not specified |
| Adults with periodontitis (aggressive) | Tetracycline + SRP | SRP | CAL | Very Low | Not specified |
| Adults with periodontitis (chronic) | Amoxicillin + clavulanate + SRP | SRP | Adverse events | Very Low | Not specified |
| Adults with periodontitis (chronic) | Amoxicillin + clavulanate + SRP | SRP | Probing pocket depth | Very Low | Not specified |
| Adults with periodontitis (chronic) | Amoxicillin + clavulanate + SRP | SRP | Percentage of BOP | Very Low | Not specified |
| Adults with periodontitis (chronic) | Amoxicillin + clavulanate + SRP | SRP | CAL | Very Low | Not specified |
| Adults with periodontitis (chronic/aggressive) | Amoxicillin + metronidazole + SRP | SRP | CAL | Very Low | Not specified |
| Adults with periodontitis (chronic/aggressive) | Amoxicillin + metronidazole + SRP | SRP | Percentage of closed pockets | Very Low | Not specified |
| Adults with periodontitis (chronic/aggressive) | Amoxicillin + metronidazole + SRP | SRP | Probing pocket depth | Very Low | Not specified |
| Adults with periodontitis (chronic/aggressive) | Amoxicillin + metronidazole + SRP | SRP | Percentage of BOP | Very Low | Not specified |
| Adults with periodontitis (chronic/aggressive) | Amoxicillin + metronidazole + SRP | SRP | Adverse events | Very Low | Not specified |
| Adults with periodontitis (chronic/aggressive) | Azithromycin + SRP | SRP | Percentage of BOP | Very Low | Not specified |
| Adults with periodontitis (chronic/aggressive) | Azithromycin + SRP | SRP | Percentage of closed pockets | Very Low | Not specified |
| Adults with periodontitis (chronic/aggressive) | Azithromycin + SRP | SRP | Adverse events | Very Low | Not specified |
| Adults with periodontitis (chronic/aggressive) | Azithromycin + SRP | SRP | CAL | Very Low | Not specified |
| Adults with periodontitis (chronic/aggressive) | Azithromycin + SRP | SRP | Probing pocket depth | Very Low | Not specified |
| Adults with periodontitis (chronic/aggressive) | Metronidazole + SRP | SRP | Percentage of closed pockets | Very Low | Not specified |
| Adults with periodontitis (chronic/aggressive) | Metronidazole + SRP | SRP | Percentage of BOP | Very Low | Not specified |
| Adults with periodontitis (chronic/aggressive) | Metronidazole + SRP | SRP | Probing pocket depth | Very Low | Not specified |
| Adults with periodontitis (chronic/aggressive) | Metronidazole + SRP | SRP | CAL | Very Low | Not specified |
| Adults with periodontitis (chronic/aggressive) | Metronidazole + SRP | SRP | Adverse events | Very Low | Not specified |
CD012595
Current Version: CD012595.PUB4
| 2 older versions
Current Evidence Gaps 29 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| school children in UK | criteria-based screening | no screening | Dental attendance | Low | Not specified |
| school children in India | traditional screening with motivation | traditional screening | Proportion of children with other treated/untreated oral health need | No Evidence Yet | N/A |
| school children in India | traditional screening with motivation | traditional screening | Adverse events | No Evidence Yet | N/A |
| school children in India | traditional screening with motivation | traditional screening | Proportion of children with treated/untreated caries | No Evidence Yet | N/A |
| school children in Saudi Arabia | referral to specific treatment facility | advice letter to see a dentist | Proportion of children with treated/untreated caries | No Evidence Yet | N/A |
| school children in Saudi Arabia | referral to specific treatment facility | advice letter to see a dentist | Adverse events | No Evidence Yet | N/A |
| school children in Saudi Arabia | referral to specific treatment facility | advice letter to see a dentist | Proportion of children with other treated/untreated oral health need | No Evidence Yet | N/A |
| school children in UK | criteria-based screening | traditional screening | Proportion of children with treated/untreated caries | No Evidence Yet | N/A |
| school children in UK | criteria-based screening | no screening | Adverse events | No Evidence Yet | N/A |
| school children in UK | criteria-based screening | no screening | Proportion of children with other treated/untreated oral health need | No Evidence Yet | N/A |
| school children in UK | criteria-based screening | no screening | Proportion of children with treated/untreated caries | No Evidence Yet | N/A |
| school children in UK | criteria-based screening | traditional screening | Proportion of children with other treated/untreated oral health need | No Evidence Yet | N/A |
| school children in UK | criteria-based screening | traditional screening | Adverse events | No Evidence Yet | N/A |
| school children in UK | criteria-based screening with specific referral | criteria-based screening with non-specific referral | Adverse events | No Evidence Yet | N/A |
| school children in UK | criteria-based screening with specific referral | criteria-based screening with non-specific referral | Proportion of children with treated/untreated caries | No Evidence Yet | N/A |
| school children in UK | criteria-based screening with specific referral | criteria-based screening with non-specific referral | Proportion of children with other treated/untreated oral health need | No Evidence Yet | N/A |
| school children in UK and India | traditional screening | no screening | Proportion of children with other treated/untreated oral health need | No Evidence Yet | N/A |
| school children in UK and India | traditional screening | no screening | Adverse events | No Evidence Yet | N/A |
| school children in UK and India | traditional screening | no screening | Proportion of children with treated/untreated caries | No Evidence Yet | N/A |
| school children in USA | CSM referral letter | standard referral letter | Dental attendance | No Evidence Yet | N/A |
| school children in USA | CSM referral letter | standard referral letter | Proportion of children with other treated/untreated oral health need | No Evidence Yet | N/A |
| school children in USA | CSM referral letter | standard referral letter | Adverse events | No Evidence Yet | N/A |
| school children in India | traditional screening with motivation | traditional screening | Dental attendance | Very Low | Not specified |
| school children in Saudi Arabia | referral to specific treatment facility | advice letter to see a dentist | Dental attendance | Very Low | Not specified |
| school children in UK | criteria-based screening | traditional screening | Dental attendance | Very Low | Not specified |
| school children in UK | criteria-based screening with specific referral | criteria-based screening with non-specific referral | Dental attendance at orthodontist | Very Low | Not specified |
| school children in UK | criteria-based screening with specific referral | criteria-based screening with non-specific referral | Dental attendance at general dentist | Very Low | Not specified |
| school children in UK and India | traditional screening | no screening | Dental attendance | Very Low | Not specified |
| school children in USA | CSM referral letter | standard referral letter | Proportion of children with treated/untreated caries | Very Low | Not specified |
Previous Versions
CD012595.PUB3
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| school children | criteria-based screening | no screening | Dental attendance | Low | - |
| school children | criteria-based screening with specific referral | criteria-based screening with non-specific referral | Dental attendance at orthodontist | Low | - |
| school children | criteria-based screening with specific referral | criteria-based screening with non-specific referral | Dental attendance at general dentist | Low | - |
| school children | traditional screening with motivation | traditional screening | Dental attendance | Low | - |
| school children | criteria-based screening | traditional screening | Dental attendance | Very Low | - |
| school children | referral letter based on common-sense model | standard referral letter | Dental care received | Very Low | - |
| school children | referral letter based on common-sense model plus dental information guide | standard referral letter | Dental care received | Very Low | - |
| school children | referral letter based on common-sense model plus dental information guide | referral letter based on common-sense model | Dental care received | Very Low | - |
| school children | traditional screening | no screening | Dental attendance | Very Low | - |
CD012595.PUB2
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| school children | criteria-based screening | no screening | Dental attendance | Low | - |
| school children | criteria-based screening with specific referral | criteria-based screening with non-specific referral | Dental attendance at orthodontist | Low | - |
| school children | criteria-based screening with specific referral | criteria-based screening with non-specific referral | Dental attendance at general dentist | Low | - |
| school children | traditional screening with motivation | traditional screening | Dental attendance | Low | - |
| increasing dental attendance | traditional screening | no screening | Dental attendance | Very Low | - |
| school children | criteria-based screening | traditional screening | Dental attendance | Very Low | - |
CD012628
Current Version: CD012628.PUB2
Current Evidence Gaps 79 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| Adults (mean age 30.9 years) (level of ID unclear) | Scheduled dental visits (oral hygiene instruction, with or without scale and polish), with supervised daily toothbrushing by carers | Usual care ("no specific treatment") | Gingival pocketing long term (> 12 months) | Low | Not specified |
| Adults (mean age 30.9 years) (level of ID unclear) | Scheduled dental visits (oral hygiene instruction, with or without scale and polish), with supervised daily toothbrushing by carers | Usual care ("no specific treatment") | Plaque long term (> 12 months) | Low | Not specified |
| Adults (mean age 30.9 years) (level of ID unclear) | Scheduled dental visits (oral hygiene instruction, with or without scale and polish), with supervised daily toothbrushing by carers | Usual care ("no specific treatment") | Gingival bleeding long term (> 12 months) | Low | Not specified |
| Children and adults with mixed levels of ID | Electric toothbrush (self, carer or carer-assisted brushing) | Manual toothbrush (self, carer or carer-assisted brushing) | Plaque medium term (6 weeks to 12 months) | Low | Not specified |
| Children and adults with mixed levels of ID | Electric toothbrush (self, carer or carer-assisted brushing) | Manual toothbrush (self, carer or carer-assisted brushing) | Gingival inflammation short term (< 6 weeks) | Low | Not specified |
| Children and adults with mixed levels of ID | Special manual toothbrush (self, carer or carer-assisted brushing) | Conventional manual toothbrush (self, carer or carer-assisted brushing) | Gingival inflammation short term (< 6 weeks) | Low | Not specified |
| People aged 15 to 30 years with mixed levels of ID | Daily toothbrushing by dental student | Twice-weekly or once-weekly toothbrushing by dental student | Plaque short term (< 6 weeks) | Low | Not specified |
| People with mixed levels of ID (age range unclear) | Training of carers | No training of carers | Knowledge medium term (6 weeks to 12 months) | Low | Not specified |
| People with mixed levels of ID (age range unclear) | Training of carers | No training of carers | Plaque medium term (6 weeks to 12 months) | Low | Not specified |
| People with mixed levels of ID (age range unclear) | Training of carers | No training of carers | Gingival inflammation medium term (6 weeks to 12 months) | Low | Not specified |
| Children and adults with mixed levels of ID | Electric toothbrush (self, carer or carer-assisted brushing) | Manual toothbrush (self, carer or carer-assisted brushing) | Gingival inflammation medium term (6 weeks to 12 months) | Moderate | Not specified |
| Adults (mean age 30.9 years) (level of ID unclear) | Scheduled dental visits (oral hygiene instruction, with or without scale and polish), with supervised daily toothbrushing by carers | Usual care ("no specific treatment") | Dental caries | No Evidence Yet | N/A |
| Adults (mean age 30.9 years) (level of ID unclear) | Scheduled dental visits (oral hygiene instruction, with or without scale and polish), with supervised daily toothbrushing by carers | Usual care ("no specific treatment") | Quality of life | No Evidence Yet | N/A |
| Adults (mean age 30.9 years) (level of ID unclear) | Scheduled dental visits (oral hygiene instruction, with or without scale and polish), with supervised daily toothbrushing by carers | Usual care ("no specific treatment") | Plaque short term (< 6 weeks) | No Evidence Yet | N/A |
| Adults (mean age 30.9 years) (level of ID unclear) | Scheduled dental visits (oral hygiene instruction, with or without scale and polish), with supervised daily toothbrushing by carers | Usual care ("no specific treatment") | Gingival inflammation short term (< 6 weeks) | No Evidence Yet | N/A |
| Adults (mean age 30.9 years) (level of ID unclear) | Scheduled dental visits (oral hygiene instruction, with or without scale and polish), with supervised daily toothbrushing by carers | Usual care ("no specific treatment") | Adverse effects | No Evidence Yet | N/A |
| Children and adults with mild to profound ID | Oral hygiene training (toothbrushing routine) | No oral hygiene training | Quality of life | No Evidence Yet | N/A |
| Children and adults with mild to profound ID | Oral hygiene training (toothbrushing routine) | No oral hygiene training | Plaque medium term (6 weeks to 12 months) | No Evidence Yet | N/A |
| Children and adults with mild to profound ID | Oral hygiene training (toothbrushing routine) | No oral hygiene training | Gingival inflammation medium term (6 weeks to 12 months) | No Evidence Yet | N/A |
| Children and adults with mild to profound ID | Oral hygiene training (toothbrushing routine) | No oral hygiene training | Dental caries | No Evidence Yet | N/A |
| Children and adults with mild to profound ID | Oral hygiene training (toothbrushing routine) | No oral hygiene training | Adverse effects | No Evidence Yet | N/A |
| Children and adults with mixed levels of ID | Electric toothbrush (self, carer or carer-assisted brushing) | Manual toothbrush (self, carer or carer-assisted brushing) | Quality of life | No Evidence Yet | N/A |
| Children and adults with mixed levels of ID | Electric toothbrush (self, carer or carer-assisted brushing) | Manual toothbrush (self, carer or carer-assisted brushing) | Adverse effects | No Evidence Yet | N/A |
| Children and adults with mixed levels of ID | Electric toothbrush (self, carer or carer-assisted brushing) | Manual toothbrush (self, carer or carer-assisted brushing) | Dental caries | No Evidence Yet | N/A |
| Children and adults with mixed levels of ID | Special manual toothbrush (self, carer or carer-assisted brushing) | Conventional manual toothbrush (self, carer or carer-assisted brushing) | Quality of life | No Evidence Yet | N/A |
| Children and adults with mixed levels of ID | Special manual toothbrush (self, carer or carer-assisted brushing) | Conventional manual toothbrush (self, carer or carer-assisted brushing) | Dental caries | No Evidence Yet | N/A |
| Children and adults with mixed levels of ID | Special manual toothbrush (self, carer or carer-assisted brushing) | Conventional manual toothbrush (self, carer or carer-assisted brushing) | Adverse effects | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| People aged 15 to 30 years with mixed levels of ID | Daily toothbrushing by dental student | Twice-weekly or once-weekly toothbrushing by dental student | Gingival inflammation short term (< 6 weeks) | No Evidence Yet | N/A |
| People aged 15 to 30 years with mixed levels of ID | Daily toothbrushing by dental student | Twice-weekly or once-weekly toothbrushing by dental student | Dental caries | No Evidence Yet | N/A |
| People aged 15 to 30 years with mixed levels of ID | Daily toothbrushing by dental student | Twice-weekly or once-weekly toothbrushing by dental student | Adverse effects | No Evidence Yet | N/A |
| People aged 15 to 30 years with mixed levels of ID | Daily toothbrushing by dental student | Twice-weekly or once-weekly toothbrushing by dental student | Quality of life | No Evidence Yet | N/A |
| People aged 15 to 30 years with mixed levels of ID | Daily toothbrushing by dental student | Twice-weekly or once-weekly toothbrushing by dental student | Plaque medium term (6 weeks to 12 months) | No Evidence Yet | N/A |
| People aged 15 to 30 years with mixed levels of ID | Daily toothbrushing by dental student | Twice-weekly or once-weekly toothbrushing by dental student | Gingival inflammation medium term (6 weeks to 12 months) | No Evidence Yet | N/A |
| People aged 15 to 30 years with mixed levels of ID | individualised care plans based on a multidisciplinary assessment | usual care â continued regular oral hygiene care, which was supported by a carer following institution's standard guidelines | Quality of life | No Evidence Yet | N/A |
| People aged 15 to 30 years with mixed levels of ID | individualised care plans based on a multidisciplinary assessment | usual care â continued regular oral hygiene care, which was supported by a carer following institution's standard guidelines | Adverse effects | No Evidence Yet | N/A |
| People aged 15 to 30 years with mixed levels of ID | individualised care plans based on a multidisciplinary assessment | usual care â continued regular oral hygiene care, which was supported by a carer following institution's standard guidelines | Gingival inflammation short term (< 6 weeks) | No Evidence Yet | N/A |
| People aged 15 to 30 years with mixed levels of ID | individualised care plans based on a multidisciplinary assessment | usual care â continued regular oral hygiene care, which was supported by a carer following institution's standard guidelines | Gingival inflammation medium term (6 weeks to 12 months) | No Evidence Yet | N/A |
| People aged 15 to 30 years with mixed levels of ID | individualised care plans based on a multidisciplinary assessment | usual care â continued regular oral hygiene care, which was supported by a carer following institution's standard guidelines | Plaque short term (< 6 weeks) | No Evidence Yet | N/A |
| People aged 15 to 30 years with mixed levels of ID | individualised care plans based on a multidisciplinary assessment | usual care â continued regular oral hygiene care, which was supported by a carer following institution's standard guidelines | Dental caries | No Evidence Yet | N/A |
| People aged 15 to 30 years with mixed levels of ID | toothpaste with a plaqueâdisclosing agent | conventional toothpaste | Plaque medium term (6 weeks to 12 months) | No Evidence Yet | N/A |
| People aged 15 to 30 years with mixed levels of ID | toothpaste with a plaqueâdisclosing agent | conventional toothpaste | Quality of life | No Evidence Yet | N/A |
| People aged 15 to 30 years with mixed levels of ID | toothpaste with a plaqueâdisclosing agent | conventional toothpaste | Gingival inflammation medium term (6 weeks to 12 months) | No Evidence Yet | N/A |
| People aged 15 to 30 years with mixed levels of ID | toothpaste with a plaqueâdisclosing agent | conventional toothpaste | Dental caries | No Evidence Yet | N/A |
| People aged 15 to 30 years with mixed levels of ID | toothpaste with a plaqueâdisclosing agent | conventional toothpaste | Adverse effects | No Evidence Yet | N/A |
| People with ID (level of ID and age unclear) | Discussion of clinical photographs as OH motivators and OH instruction at monthly intervals | No discussion of clinical photographs, but did receive OH instruction at monthly intervals | Quality of life | No Evidence Yet | N/A |
| People with ID (level of ID and age unclear) | Discussion of clinical photographs as OH motivators and OH instruction at monthly intervals | No discussion of clinical photographs, but did receive OH instruction at monthly intervals | Gingival inflammation short term (< 6 weeks) | No Evidence Yet | N/A |
| People with ID (level of ID and age unclear) | Discussion of clinical photographs as OH motivators and OH instruction at monthly intervals | No discussion of clinical photographs, but did receive OH instruction at monthly intervals | Gingival inflammation medium term (6 weeks to 12 months) | No Evidence Yet | N/A |
| People with ID (level of ID and age unclear) | Discussion of clinical photographs as OH motivators and OH instruction at monthly intervals | No discussion of clinical photographs, but did receive OH instruction at monthly intervals | Plaque short term (< 6 weeks) | No Evidence Yet | N/A |
| People with ID (level of ID and age unclear) | Discussion of clinical photographs as OH motivators and OH instruction at monthly intervals | No discussion of clinical photographs, but did receive OH instruction at monthly intervals | Dental caries | No Evidence Yet | N/A |
| People with ID (level of ID and age unclear) | Discussion of clinical photographs as OH motivators and OH instruction at monthly intervals | No discussion of clinical photographs, but did receive OH instruction at monthly intervals | Adverse effects | No Evidence Yet | N/A |
| People with mixed levels of ID (age range unclear) | Training of carers | No training of carers | Gingival inflammation short term (< 6 weeks) | No Evidence Yet | N/A |
| People with mixed levels of ID (age range unclear) | Training of carers | No training of carers | Quality of life | No Evidence Yet | N/A |
| People with mixed levels of ID (age range unclear) | Training of carers | No training of carers | Dental caries | No Evidence Yet | N/A |
| People with mixed levels of ID (age range unclear) | Training of carers | No training of carers | Adverse effects | No Evidence Yet | N/A |
| People with mixed levels of ID (age range unclear) | Training of carers | No training of carers | Plaque short term (< 6 weeks) | No Evidence Yet | N/A |
| Children and adults with mild to profound ID | Oral hygiene training (toothbrushing routine) | No oral hygiene training | Behaviour, attitude and self-efficacy medium and long term (6 weeks to > 12 months) | Very Low | Not specified |
| Children and adults with mild to profound ID | Oral hygiene training (toothbrushing routine) | No oral hygiene training | Plaque short term (< 6 weeks) | Very Low | Not specified |
| Children and adults with mild to profound ID | Oral hygiene training (toothbrushing routine) | No oral hygiene training | Gingival inflammation short term (< 6 weeks) | Very Low | Not specified |
| Children and adults with mixed levels of ID | Electric toothbrush (self, carer or carer-assisted brushing) | Manual toothbrush (self, carer or carer-assisted brushing) | Plaque short term (< 6 weeks) | Very Low | Not specified |
| Children and adults with mixed levels of ID | Special manual toothbrush (self, carer or carer-assisted brushing) | Conventional manual toothbrush (self, carer or carer-assisted brushing) | Plaque short term | Very Low | Not specified |
| Children and adults with mixed levels of ID | Special manual toothbrush (self, carer or carer-assisted brushing) | Conventional manual toothbrush (self, carer or carer-assisted brushing) | Gingival inflammation medium term (6 weeks to 12 months) | Very Low | Not specified |
| Children and adults with mixed levels of ID | Special manual toothbrush (self, carer or carer-assisted brushing) | Conventional manual toothbrush (self, carer or carer-assisted brushing) | Plaque medium term (6 weeks to 12 months) | Very Low | Not specified |
| People aged 15 to 30 years with mixed levels of ID | individualised care plans based on a multidisciplinary assessment | usual care â continued regular oral hygiene care, which was supported by a carer following institution's standard guidelines | Plaque medium term (6 weeks to 12 months) | Very Low | Not specified |
| People aged 15 to 30 years with mixed levels of ID | toothpaste with a plaqueâdisclosing agent | conventional toothpaste | Gingival inflammation short term (< 6 weeks) | Very Low | Not specified |
| People aged 15 to 30 years with mixed levels of ID | toothpaste with a plaqueâdisclosing agent | conventional toothpaste | Plaque short term (< 6 weeks) | Very Low | Not specified |
| People with ID (level of ID and age unclear) | Discussion of clinical photographs as OH motivators and OH instruction at monthly intervals | No discussion of clinical photographs, but did receive OH instruction at monthly intervals | Plaque medium term (6 weeks to 12 months) | Very Low | Not specified |
| People with mixed levels of ID (age range unclear) | Training of carers | No training of carers | Behaviour, attitude and self-efficacy (BAS) medium term (6 weeks to 12 months) | Very Low | Not specified |
CD012851
Current Version: CD012851.PUB2
Current Evidence Gaps 4 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| young people aged 9â14 years | double primary tooth (canine and molar) extractions | single primary tooth (canine) extraction | Referred for surgical exposure of the unerupted PDC by maximum 48 months | Very Low | Not specified |
| young people aged 9â14 years | double primary tooth (canine and molar) extractions | single primary tooth (canine) extraction | Eruption of PDC at mean 18 months | Very Low | Not specified |
| young people aged 9â14 years | single primary tooth (canine) extraction | no extraction | Referral for surgical exposure of PDC at 12 months | Very Low | Not specified |
| young people aged 9â14 years | single primary tooth (canine) extraction | no extraction | Eruption of PDC at 12 months | Very Low | Not specified |
CD012981
Current Version: CD012981.PUB2
Current Evidence Gaps 23 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| children who were regular dental attenders with cariesâfree first or second primary molars | flowable resin composite | resinâbased sealants | Sealant retention, 12 months | Low | Not specified |
| children with cariesâfree (or nonâcavitated carious lesion) primary molars, aged 3â7 years | fluorideâreleasing resinâbased sealant | no treatment | Development of ⥠1 new carious lesion (caries incidence), 12 months | Low | Not specified |
| children with cariesâfree (or nonâcavitated carious lesion) primary molars, aged 3â7 years | fluorideâreleasing resinâbased sealant | no treatment | Development of ⥠1 new carious lesion (caries incidence), 24 months | Low | Not specified |
| children with cariesâfree primary first molars with or without caries affecting other teeth, aged 1â5 years | glass ionomerâbased sealants | no sealants | Development of at ⥠1 new carious lesion (caries incidence), 12-30 months | Low | Not specified |
| children with caries?free second primary molars, aged 48 years | fluoride?releasing resin?based sealants | resin?based sealants | Development of ? 1 new carious lesion (caries incidence) | Low | Not specified |
| children who were regular dental attenders with cariesâfree first or second primary molars | flowable resin composite | resinâbased sealants | Development of ⥠1 new carious lesion (caries incidence) | No Evidence Yet | N/A |
| children who were regular dental attenders with cariesâfree first or second primary molars | flowable resin composite | resinâbased sealants | Progression of nonâcavitated enamel caries | No Evidence Yet | N/A |
| children who were regular dental attenders with cariesâfree first or second primary molars | flowable resin composite | resinâbased sealants | Adverse events | No Evidence Yet | N/A |
| children with cariesâfree (or nonâcavitated carious lesion) primary molars, aged 3â7 years | fluorideâreleasing resinâbased sealant | no treatment | Progression of nonâcavitated enamel caries | No Evidence Yet | N/A |
| children with cariesâfree (or nonâcavitated carious lesion) primary molars, aged 3â7 years | fluorideâreleasing resinâbased sealant | no treatment | Adverse events | No Evidence Yet | N/A |
| children with cariesâfree primary first molars with or without caries affecting other teeth, aged 1â5 years | glass ionomerâbased sealants | no sealants | Progression of nonâcavitated enamel caries | No Evidence Yet | N/A |
| children with cariesâfree primary first molars with or without caries affecting other teeth, aged 1â5 years | glass ionomerâbased sealants | no sealants | Adverse events | No Evidence Yet | N/A |
| children with caries?free second primary molars, aged 48 years | fluoride?releasing resin?based sealants | resin?based sealants | Progression of non?cavitated enamel caries | No Evidence Yet | N/A |
| children with caries?free second primary molars, aged 48 years | fluoride?releasing resin?based sealants | resin?based sealants | Adverse events | No Evidence Yet | N/A |
| children with sound primary molars, aged 2â4 years | autopolymerised sealant application | light polymerised sealant application | Progression of nonâcavitated enamel caries | No Evidence Yet | N/A |
| children with sound primary molars, aged 2â4 years | autopolymerised sealant application | light polymerised sealant application | Adverse events | No Evidence Yet | N/A |
| 'healthy' children, with cariesâfree second primary molars, aged 3â5 years | glass ionomerâbased sealants | fluorideâreleasing or nonâfluorideâreleasing resinâbased sealants | Progression of nonâcavitated enamel caries | No Evidence Yet | N/A |
| children with caries?free second primary molars, aged 48 years | fluoride?releasing resin?based sealants | resin?based sealants | Sealant retention | Very Low | Not specified |
| children with sound primary molars, aged 2â4 years | autopolymerised sealant application | light polymerised sealant application | Sealant retention, 24â36 months | Very Low | Not specified |
| children with sound primary molars, aged 2â4 years | autopolymerised sealant application | light polymerised sealant application | Development of ⥠1 new carious lesion (caries incidence), 24â36 months | Very Low | Not specified |
| 'healthy' children, with cariesâfree second primary molars, aged 3â5 years | glass ionomerâbased sealants | fluorideâreleasing or nonâfluorideâreleasing resinâbased sealants | Adverse events | Very Low | Not specified |
| 'healthy' children, with cariesâfree second primary molars, aged 3â5 years | glass ionomerâbased sealants | fluorideâreleasing or nonâfluorideâreleasing resinâbased sealants | Development of ⥠1 new carious lesion (caries incidence), 6â24 months | Very Low | Not specified |
| 'healthy' children, with cariesâfree second primary molars, aged 3â5 years | glass ionomerâbased sealants | fluorideâreleasing or nonâfluorideâreleasing resinâbased sealants | Sealant retention, 24 months | Very Low | Not specified |
CD013039
Current Version: CD013039.PUB2
Current Evidence Gaps 13 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| treating cavitated or dentine carious lesions, primary dentition | nonâselective carious tissue removal and CR | HT | Failure of therapy | Low | Not specified |
| treating cavitated or dentine carious lesions, primary and permanent dentition | nonâselective carious tissue removal and CR | SW | Failure of therapy: CR vs SW â permanent, deep | Moderate | Not specified |
| treating cavitated or dentine carious lesions, primary and permanent dentition | SE | SW | Failure of therapy: SW vs SE â permanent, deep | Moderate | Not specified |
| treating cavitated or dentine carious lesions | nonâselective carious tissue removal and CR | SE | Failure of therapy: CR vs SE â primary, deep | Very Low | Not specified |
| treating cavitated or dentine carious lesions | nonâselective carious tissue removal and CR | SE | Failure of therapy: CR vs SE â permanent, deep | Very Low | Not specified |
| treating cavitated or dentine carious lesions | nonâselective carious tissue removal and CR | SE | Failure of therapy: CR vs SE â primary, cavitated but not deep | Very Low | Not specified |
| treating cavitated or dentine carious lesions, permanent dentition | sealing | no treatment | Failure of therapy | Very Low | Not specified |
| treating cavitated or dentine carious lesions, permanent or primary dentition | sealing using sealant materials | nonâselective carious tissue removal and CR | Failure of therapy | Very Low | Not specified |
| treating cavitated or dentine carious lesions, primary and permanent dentition | nonâselective carious tissue removal and CR | SW | Failure of therapy: CR vs SW â primary, deep | Very Low | Not specified |
| treating cavitated or dentine carious lesions, primary and permanent dentition | SE | SW | Failure of therapy: SW vs SE â primary, deep | Very Low | Not specified |
| treating cavitated or dentine carious lesions, primary dentition | HT | NRCC | Failure of therapy | Very Low | Not specified |
| treating cavitated or dentine carious lesions, primary dentition | nonâselective carious tissue removal and CR | NRCC | Failure of therapy | Very Low | Not specified |
| treating cavitated or dentine carious lesions, primary dentition | SE | HT | Failure of therapy: SE vs HT â primary, deep | Very Low | Not specified |
| treating cavitated or dentine carious lesions, primary dentition | SE | HT | Failure of therapy: SE vs HT â primary, cavitated but not deep | Very Low | Not specified |
| treating cavitated or dentine carious lesions, primary dentition | sealing with sealant materials | SE | Failure of therapy | Very Low | Not specified |
CD013515
Current Version: CD013515.PUB2
Current Evidence Gaps 14 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| People with painful TMD | CBT | Usual care, waiting list or no treatment | Pain intensity at treatment completion | Low | Not specified |
| People with painful TMD | CBT | Alternative treatment | Pain intensity at treatment completion | Low | Not specified |
| People with painful TMD | CBT | Alternative treatment | Pain intensity at follow-up (6-12 months) | Low | Not specified |
| People with painful TMD | CBT | Alternative treatment | Disability caused by pain at treatment completion | Low | Not specified |
| People with painful TMD | CBT | Alternative treatment | Disability caused by pain at follow-up | Low | Not specified |
| People with painful TMD | CBT | Alternative treatment | Psychological distress at treatment completion | Low | Not specified |
| People with painful TMD | CBT | Alternative treatment | Psychological distress at follow-up | Low | Not specified |
| People with painful TMD | CBT | Usual care, waiting list or no treatment | Pain intensity at follow-up (12 months) | Low | Not specified |
| People with painful TMD | CBT | Usual care, waiting list or no treatment | Pain disability at treatment completion | Low | Not specified |
| People with painful TMD | CBT | Usual care, waiting list or no treatment | Pain disability at follow-up | Low | Not specified |
| People with painful TMD | CBT | Usual care, waiting list or no treatment | Psychological distress at treatment completion | Low | Not specified |
| People with painful TMD | CBT | Usual care, waiting list or no treatment | Psychological distress at follow-up | Low | Not specified |
| People with painful TMD | CBT | Alternative treatment | Adverse events | Very Low | Not specified |
| People with painful TMD | CBT | Usual care, waiting list or no treatment | Adverse events | Very Low | Not specified |
CD013686
Current Version: CD013686.PUB2
Current Evidence Gaps 18 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| people undergoing aerosol generating procedures | high-volume evacuation (HVE) | no HVE | Rate of infection of dental staff or patients | No Evidence Yet | N/A |
| people undergoing aerosol generating procedures | high-volume evacuation (HVE) | no HVE | Reduction in volume of contaminated aerosols in the operative environment | No Evidence Yet | N/A |
| people undergoing aerosol generating procedures | HVE | conventional dental suction | Rate of infection of dental staff or patients | No Evidence Yet | N/A |
| people undergoing aerosol generating procedures | HVE | conventional dental suction | Reduction in volume of contaminated aerosols in the operative environment | No Evidence Yet | N/A |
| people undergoing aerosol generating procedures | rubber dam | no rubber dam | Reduction in volume of contaminated aerosols in the operative environment | No Evidence Yet | N/A |
| people undergoing aerosol generating procedures | rubber dam | no rubber dam | Rate of infection of dental staff or patients | No Evidence Yet | N/A |
| people undergoing aerosol generating procedures | rubber dam + HVE | no rubber dam + HVE | Rate of infection of dental staff or patients | No Evidence Yet | N/A |
| people undergoing aerosol generating procedures | rubber dam + HVE | no rubber dam + HVE | Reduction in volume of contaminated aerosols in the operative environment | No Evidence Yet | N/A |
| people undergoing aerosol generating procedures | high-volume evacuation (HVE) | no HVE | Reduction in level of contamination in aerosols (CFU/mm³) during ultrasonic scaling and air polishing at more than 1 foot from oral cavity | Very Low | Not specified |
| people undergoing aerosol generating procedures | high-volume evacuation (HVE) | no HVE | Reduction in level of contamination in aerosols (CFU/mm³) during ultrasonic scaling and air polishing at less than 1 foot from oral cavity | Very Low | Not specified |
| people undergoing aerosol generating procedures | HVE | conventional dental suction | Reduction in level of contamination in aerosols during ultrasonic scaling at 40 cm | Very Low | Not specified |
| people undergoing aerosol generating procedures | HVE | conventional dental suction | Reduction in level of contamination in aerosols during ultrasonic scaling at 150 cm | Very Low | Not specified |
| people undergoing aerosol generating procedures | rubber dam | no rubber dam | Reduction in the level of contamination in aerosols during restorative procedures at 2 meters from mouth | Very Low | Not specified |
| people undergoing aerosol generating procedures | rubber dam | no rubber dam | Reduction in the level of contamination in aerosols during restorative procedures at forehead | Very Low | Not specified |
| people undergoing aerosol generating procedures | rubber dam | no rubber dam | Reduction in level of contamination in aerosols during restorative procedures at 1 meter from mouth | Very Low | Not specified |
| people undergoing aerosol generating procedures | rubber dam | no rubber dam | Reduction in the level of contamination in aerosols during restorative procedures at occiput | Very Low | Not specified |
| people undergoing aerosol generating procedures | rubber dam + HVE | no rubber dam + HVE | Reduction in level of contamination in aerosols during restorative procedures at dental unit light | Very Low | Not specified |
| people undergoing aerosol generating procedures | rubber dam + HVE | no rubber dam + HVE | Reduction in level of contamination in aerosols during restorative procedures at participant's chest | Very Low | Not specified |
CD013826
Current Version: CD013826.PUB2
Current Evidence Gaps 57 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | essential oils/herbal mouthwash | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â assistant level | Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | essential oils/herbal mouthwash | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â operator level | Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental healthcare professionals treating them | CHX | water | Reduction in the level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â combined operator, assistant and patient level | Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | saline | Incidence of infection of dental healthcare providers | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | saline | Adverse events such as transient discolouration, altered taste, allergic reaction, hypersensitivity | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | saline | Reduction in the level of contamination by particles ?5 µm (droplet nuclei) at distances of ? 2 m from patient's oral cavity in the operative environment | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | CPC | Adverse events such as transient discolouration, altered taste, allergic reaction, hypersensitivity | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | CPC | Reduction in level of contamination by particles ? 5 µm (droplet nuclei) at distances of ? 2 m from patient's oral cavity in the operative environment | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | CPC | Incidence of infection of dental healthcare providers | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | povidone iodine | Adverse events such as transient discolouration, altered taste, allergic reaction, hypersensitivity | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | povidone iodine | Incidence of infection of dental healthcare providers | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | essential oils/herbal mouthwash | Adverse events such as transient discolouration, altered taste, allergic reaction, hypersensitivity | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | essential oils/herbal mouthwash | Reduction in level of contamination by particles ? 5 µm (droplet nuclei) at distances of ? 2 m from patient's oral cavity in the operative environment | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | essential oils/herbal mouthwash | Incidence of infection of dental healthcare providers | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | tempered CHX | nonâtempered CHX | Adverse events such as transient discolouration, altered taste, allergic reaction, hypersensitivity | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | tempered CHX | nonâtempered CHX | Incidence of infection of dental healthcare providers | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | tempered CHX | nonâtempered CHX | Reduction in the level of contamination by particles ?5 µm (droplet nuclei) at distances of ? 2 m from patient's oral cavity in the operative environment | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental healthcare professionals treating them | CHX | no rinsing | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment operator level | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental healthcare professionals treating them | CHX | no rinsing | Incidence of infection of dental healthcare providers | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental healthcare professionals treating them | CHX | no rinsing | Adverse events such as transient discolouration, altered taste, allergic reaction, hypersensitivity | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental healthcare professionals treating them | CHX | water | Incidence of infection of dental healthcare providers | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental healthcare professionals treating them | CHX | water | Reduction in level of contamination by particles ?5 µm (droplet nuclei) at distances of ? 2 m from patient's oral cavity in the operative environment | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental healthcare professionals treating them | CHX | water | Adverse events such as transient discolouration, altered taste, allergic reaction, hypersensitivity | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental healthcare professionals treating them | CHX | no rinsing | Reduction in level of contamination by particles ?5 µm (droplet nuclei) at distances of ? 2 m from patient's oral cavity in the operative environment | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | saline | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â operator level | Very Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | povidone iodine | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â operator level (aerobic cultures) | Very Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | povidone iodine | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â operator level (aerobic and anaerobic cultures combined) | Very Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | povidone iodine | Reduction in level of contamination by particles ⤠5 µm (droplet nuclei) at distances of ⥠2 m from patient's oral cavity in the operative environment â aerobic cultures | Very Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | povidone iodine | Reduction in level of contamination by particles ⤠5 µm (droplet nuclei) at distances of ⥠2 m from patient's oral cavity in the operative environment â anaerobic cultures | Very Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | CPC | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â operator | Very Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | CPC | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â assistant | Very Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | CPC | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â operator | Very Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | CPC | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â assistant | Very Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | CPC | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â operator | Very Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | CPC | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â assistant | Very Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | CPC | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â operator | Very Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | CPC | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â assistant | Very Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | CHX | CPC | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â operator level | Very Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | tempered CHX | nonâtempered CHX | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â combined | Very Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | tempered CHX | nonâtempered CHX | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â operator level | Very Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental care professionals treating them | tempered CHX | nonâtempered CHX | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â assistant level | Very Low | Not specified |
| dental patients undergoing aerosolâgenerating procedures and dental healthcare professionals treating them | CHX | water | Reduction in level of contamination by particles > 5 µm (droplets) at distances of < 2 m from patient's oral cavity in the operative environment â combined patient and operator level | Very Low | Not specified |
Showing 201 to 214 of 214 review series
Summary Statistics
214
Review Series
3688
PICO Questions
Evidence Certainty
High
(%)
Moderate
(%)
Low
(%)
Very Low
(%)
No Evidence Yet
(%)
GRADE Downgrading Reasons
Risk of Bias
985
(85.8%)
Imprecision
895
(78.0%)
Inconsistency
253
(22.0%)
Indirectness
188
(16.4%)
Publication Bias
48
(4.2%)