Evidence Gaps Analysis
3688 outcomes from 214 review series
CD005293
Current Version: CD005293.PUB2
Current Evidence Gaps 6 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| Patients with altered sensation due to inferior alveolar nerve injury | Low-level laser treatment (photon-plus GaA1As diode laser; Rønvig Dental, Denmark: 70 mW output, continuous wavelength of 820 nm) | Placebo laser treatment | Adverse events | No Evidence Yet | N/A |
| Patients with altered sensation due to inferior alveolar nerve injury | Low-level laser treatment (photon-plus GaA1As diode laser; Rønvig Dental, Denmark: 70 mW output, continuous wavelength of 820 nm) | Placebo laser treatment | Taste | No Evidence Yet | N/A |
| Patients with altered sensation due to inferior alveolar nerve injury | Low-level laser treatment (photon-plus GaA1As diode laser; Rønvig Dental, Denmark: 70 mW output, continuous wavelength of 820 nm) | Placebo laser treatment | Pain | No Evidence Yet | N/A |
| Patients with altered sensation due to inferior alveolar nerve injury | Low-level laser treatment (photon-plus GaA1As diode laser; Rønvig Dental, Denmark: 70 mW output, continuous wavelength of 820 nm) | Placebo laser treatment | Difficulty eating | No Evidence Yet | N/A |
| Patients with altered sensation due to inferior alveolar nerve injury | Low-level laser treatment (photon-plus GaA1As diode laser; Rønvig Dental, Denmark: 70 mW output, continuous wavelength of 820 nm) | Placebo laser treatment | Difficulty speaking | No Evidence Yet | N/A |
| Patients with altered sensation due to inferior alveolar nerve injury | Low-level laser treatment (photon-plus GaA1As diode laser; Rønvig Dental, Denmark: 70 mW output, continuous wavelength of 820 nm) | Placebo laser treatment | Sensation of the chin (spontaneous or evoked - anaesthesia/paraesthesia/dysaesthesia/hyperalgesia/allodynia) | Very Low | Not specified |
CD005296
Current Version: CD005296.PUB4
| 2 older versions
Current Evidence Gaps 6 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| people receiving endodontic treatment of permanent teeth | single-visit treatment | multiple-visit treatment | Pain (dichotomous) - pain in the immediate postobturation period (until 72 hours postobturation) | Low | Not specified |
| people receiving endodontic treatment of permanent teeth | single-visit treatment | multiple-visit treatment | Pain (dichotomous) - post-treatment pain (within 1 week) | Moderate | Not specified |
| people receiving endodontic treatment of permanent teeth | single-visit treatment | multiple-visit treatment | Radiological failure | Moderate | Not specified |
| people receiving endodontic treatment of permanent teeth | single-visit treatment | multiple-visit treatment | Tooth extraction | Very Low | Not specified |
| people receiving endodontic treatment of permanent teeth | single-visit treatment | multiple-visit treatment | Pain (dichotomous) - postobturation pain at 1 week | Very Low | Not specified |
| people receiving endodontic treatment of permanent teeth | single-visit treatment | multiple-visit treatment | Swelling or flare-up | Very Low | Not specified |
| people receiving endodontic treatment of permanent teeth | single-visit treatment | multiple-visit treatment | Presence of sinus tract or fistula | Very Low | Not specified |
| people receiving endodontic treatment of permanent teeth | single-visit treatment | multiple-visit treatment | Analgesic use | Very Low | Not specified |
Previous Versions
CD005296.PUB3
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| people receiving endodontic treatment of permanent teeth | single-visit treatment | multiple-visit treatment | Pain (dichotomous) - pain at 1 week | Low | - |
| people receiving endodontic treatment of permanent teeth | single-visit treatment | multiple-visit treatment | Radiological failure | Low | - |
| people receiving endodontic treatment of permanent teeth | single-visit treatment | multiple-visit treatment | Swelling or flare-up | Low | - |
| people receiving endodontic treatment of permanent teeth | single-visit treatment | multiple-visit treatment | Sinus track or fistula formation | Low | - |
| people receiving endodontic treatment of permanent teeth | single-visit treatment | multiple-visit treatment | Pain (dichotomous) - pain in the immediate postoperative period (until 72 hours postobturation) | Moderate | - |
| people receiving endodontic treatment of permanent teeth | single-visit treatment | multiple-visit treatment | Painkiller use | Moderate | - |
| people receiving endodontic treatment of permanent teeth | single-visit treatment | multiple-visit treatment | Any complication | Moderate | - |
| people receiving endodontic treatment of permanent teeth | single-visit treatment | multiple-visit treatment | Tooth extraction due to endodontic problems | Very Low | - |
CD005296.PUB2
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| Patients requiring root canal treatment | Single visit RoCT | Multiple visit RoCT | Pain at 1 week | No Evidence Yet | - |
| Patients requiring root canal treatment | Single visit RoCT | Multiple visit RoCT | Postoperative pain (72 hours) | No Evidence Yet | - |
| Patients requiring root canal treatment | Single visit RoCT | Multiple visit RoCT | Swelling/flare-up | No Evidence Yet | - |
| Patients requiring root canal treatment | Single visit RoCT | Multiple visit RoCT | Radiological failure | No Evidence Yet | - |
| Patients requiring root canal treatment | Single visit RoCT | Multiple visit RoCT | Painkiller use | No Evidence Yet | - |
| Patients with necrotic teeth | Single visit RoCT | Multiple visit RoCT | Radiological failure | No Evidence Yet | - |
CD005511
Current Version: CD005511.PUB3
| 1 older version
Current Evidence Gaps 87 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| People requiring retreatment of periapical lesions | Calcium sulphate | No grafting | Healing - 1 year | Low | Not specified |
| People requiring retreatment of periapical lesions | Endoscope | Microscope | Healing at 2 years | Low | Not specified |
| People requiring retreatment of periapical lesions | Endoscope | Loupes | Healing at 1 year | Low | Not specified |
| People requiring retreatment of periapical lesions | GTR + Bovine bone | No grafting | Healing - 1 year | Low | Not specified |
| People requiring retreatment of periapical lesions | MTA | SuperEBA | Healing at 1 year | Low | Not specified |
| People requiring retreatment of periapical lesions | MTA | IRM | Healing at 1 year | Low | Not specified |
| People requiring retreatment of periapical lesions | MTA | IRM | Prevalence of pain at 1 day | Low | Not specified |
| People requiring retreatment of periapical lesions | MTA | Gutta-percha | Healing - 1 year | Low | Not specified |
| People requiring retreatment of periapical lesions | MTA | Gutta-percha | Pain assessed with visual analogue scale (VAS) from 0 to 100 - 1 day | Low | Not specified |
| People requiring retreatment of periapical lesions | PRGF gel | No grafting | Pain assessed with visual analogue scale (VAS) from 0 to 100 - 1 day | Low | Not specified |
| People requiring retreatment of periapical lesions | Root-end resection (with root-end filling) | Root canal retreatment | Prevalence of pain - 1 day | Low | Not specified |
| People requiring retreatment of periapical lesions | Ultrasonic instruments | Bur | Healing at 1 year | Low | Not specified |
| People requiring retreatment of periapical lesions | CBCT | Periapical radiography | Maximum pain assessed with verbal rating scale (VRS) | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | CBCT | Periapical radiography | Pain assessed with visual analogue scale (VAS) from 0 to 100 - 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | CBCT | Periapical radiography | Occurrence of postoperative infection - 4 weeks | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | CBCT | Periapical radiography | Prevalence of pain - 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | CBCT | Periapical radiography | Height loss of interdental papilla | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Endoscope | loupes or microscope | Height loss of interdental papilla | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Endoscope | loupes or microscope | Maximum pain assessed with verbal rating scale (VRS) | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Endoscope | loupes or microscope | Pain assessed with visual analogue scale (VAS) from 0 to 100 at 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Endoscope | loupes or microscope | Prevalence of pain at 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Endoscope | loupes or microscope | Occurrence of postoperative infection at 4 weeks | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Glass ionomer cement | Amalgam | Occurrence of postoperative infection at 4 weeks | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Glass ionomer cement | Amalgam | Height loss of interdental papilla - 1 year | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Glass ionomer cement | Amalgam | Maximum pain assessed with verbal rating scale (VRS) | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Glass ionomer cement | Amalgam | Pain assessed with visual analogue scale (VAS) from 0 to 100 - 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Glass ionomer cement | Amalgam | Prevalence of pain at 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | grafting | No grafting | Maximum pain assessed with verbal rating scale (VRS) | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | grafting | No grafting | Height loss of interdental papilla - 1 year | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | grafting | No grafting | Occurrence of postoperative infection at 4 weeks | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | grafting | No grafting | Prevalence of pain at 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | IRM | Gutta-percha | Maximum pain assessed with verbal rating scale (VRS) | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | IRM | Gutta-percha | Pain assessed with visual analogue scale (VAS) from 0 to 100 - 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | IRM | Gutta-percha | Prevalence of pain at 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | IRM | Gutta-percha | Height loss of interdental papilla - 1 year | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | IRM | Gutta-percha | Occurrence of postoperative infection at 4 weeks | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | LLLT | Placebo | Pain assessed with visual analogue scale (VAS) from 0 to 100 - 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | LLLT | Placebo | Occurrence of postoperative infection at 4 weeks | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | LLLT | Placebo | Prevalence of pain at 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | LLLT | Placebo | Height loss of interdental papilla - 1 year | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | LLLT | Placebo | Healing - 1 year | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | MTA | Gutta-percha | Maximum pain assessed with verbal rating scale (VRS) | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | MTA | Gutta-percha | Prevalence of pain at 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | MTA | Gutta-percha | Occurrence of postoperative infection at 4 weeks | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | MTA | Gutta-percha | Height loss of interdental papilla - 1 year | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | MTA | IRM | Height loss of interdental papilla - 1 year | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | MTA | IRM | Maximum pain assessed with verbal rating scale (VRS) | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | MTA | IRM | Pain assessed with visual analogue scale (VAS) from 0 to 100 - 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | MTA | SuperEBA | Pain assessed with visual analogue scale (VAS) from 0 to 100 - 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | MTA | SuperEBA | Prevalence of pain at 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | MTA | SuperEBA | Occurrence of postoperative infection at 4 weeks | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | MTA | SuperEBA | Height loss of interdental papilla - 1 year | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | MTA | SuperEBA | Maximum pain assessed with verbal rating scale (VRS) | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | MTA | IRM | Occurrence of postoperative infection at 4 weeks | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | PBI | Complete mobilisation | Maximum pain assessed with verbal rating scale (VRS) | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | PBI | Complete mobilisation | Occurrence of postoperative infection at 4 weeks | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | PBI | Complete mobilisation | Prevalence of pain at 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | PBI | Complete mobilisation | Healing at 1 year | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Preoperative antibiotic prophylaxis | Placebo | Maximum pain assessed with verbal rating scale (VRS) | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Preoperative antibiotic prophylaxis | Placebo | Height loss of interdental papilla | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Preoperative antibiotic prophylaxis | Placebo | Prevalence of pain - 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Preoperative antibiotic prophylaxis | Placebo | Pain assessed with visual analogue scale (VAS) from 0 to 100 - 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Preoperative antibiotic prophylaxis | Placebo | Healing - 1 year | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Root-end resection (with root-end filling) | Root canal retreatment | Maximum pain assessed with verbal rating scale (VRS) | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Root-end resection (with root-end filling) | Root canal retreatment | Height loss of interdental papilla | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Root-end resection (with root-end filling) | Root canal retreatment | Occurrence of postoperative infection - 4 weeks | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Root-end resection (with root-end filling) | Root canal retreatment | Pain assessed with visual analogue scale (VAS) from 0 to 100 - 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | SuperEBA | IRM | Pain assessed with visual analogue scale (VAS) from 0 to 100 - 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | SuperEBA | IRM | Prevalence of pain at 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | SuperEBA | IRM | Height loss of interdental papilla - 1 year | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | SuperEBA | IRM | Occurrence of postoperative infection at 4 weeks | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | SuperEBA | IRM | Maximum pain assessed with verbal rating scale (VRS) | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Ultrasonic instruments | Bur | Maximum pain assessed with verbal rating scale (VRS) | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Ultrasonic instruments | Bur | Pain assessed with visual analogue scale (VAS) from 0 to 100 - 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Ultrasonic instruments | Bur | Prevalence of pain at 1 day | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Ultrasonic instruments | Bur | Occurrence of postoperative infection at 4 weeks | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | Ultrasonic instruments | Bur | Height loss of interdental papilla - 1 year | No Evidence Yet | N/A |
| People requiring retreatment of periapical lesions | CBCT | Periapical radiography | Healing - 1 year | Very Low | Not specified |
| People requiring retreatment of periapical lesions | Glass ionomer cement | Amalgam | Healing - 1 year | Very Low | Not specified |
| People requiring retreatment of periapical lesions | IRM | Gutta-percha | Healing - 1 year | Very Low | Not specified |
| People requiring retreatment of periapical lesions | LLLT | Control | Maximum pain assessed with verbal rating scale (VRS) | Very Low | Not specified |
| People requiring retreatment of periapical lesions | LLLT | Placebo | Maximum pain assessed with verbal rating scale (VRS) | Very Low | Not specified |
| People requiring retreatment of periapical lesions | PBI | Complete mobilisation | Height loss of interdental papilla - 1 year | Very Low | Not specified |
| People requiring retreatment of periapical lesions | PBI | Complete mobilisation | Pain assessed with visual analogue scale (VAS) from 0 to 100 - 1 day | Very Low | Not specified |
| People requiring retreatment of periapical lesions | Preoperative antibiotic prophylaxis | Placebo | Occurrence of postoperative infection - 4 weeks | Very Low | Not specified |
| People requiring retreatment of periapical lesions | Root-end resection (with root-end filling) | Root canal retreatment | Healing - 1 year | Very Low | Not specified |
| People requiring retreatment of periapical lesions | SuperEBA | IRM | Healing - 1 year | Very Low | Not specified |
Previous Versions
CD005511.PUB2
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| Patients with periapical lesions | Surgical retreatment | Non-surgical retreatment | 1-year healing rate (random effects) | No Evidence Yet | - |
| Patients with periapical lesions | Surgical retreatment | Non-surgical retreatment | Post-operative pain and swelling | No Evidence Yet | - |
| Patients with periapical lesions | Surgical retreatment | Non-surgical retreatment | 4-year healing rate | No Evidence Yet | - |
| Patients with periapical lesions | Surgical retreatment | Non-surgical retreatment | 2-year healing rate | No Evidence Yet | - |
| Patients with periapical lesions | Surgical retreatment | Non-surgical retreatment | 1-year healing rate | No Evidence Yet | - |
CD005512
Current Version: CD005512.PUB3
| 1 older version
Current Evidence Gaps 9 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| decayed primary molar teeth | preformed crown | filling | Gingival bleeding - long term (12 months) | Low | Not specified |
| decayed primary molar teeth | preformed crown | filling | Pain - long term (12 months to 24 months) | Moderate | Not specified |
| decayed primary molar teeth | preformed crown | filling | Major failure - long term (12 months to 48 months) | Moderate | Not specified |
| decayed primary molar teeth | preformed crown | filling | Discomfort associated with the procedure | Moderate | Not specified |
| children with decayed primary molar teeth | preformed crown | non-restorative caries treatment | Satisfaction with treatment | No Evidence Yet | N/A |
| children with decayed primary molar teeth | preformed crown | non-restorative caries treatment | Pain | No Evidence Yet | N/A |
| decayed primary molar teeth | preformed crown | filling | Satisfaction with treatment | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| nan | nan | nan | nan | No Evidence Yet | N/A |
| children with decayed primary molar teeth | preformed crown | non-restorative caries treatment | Discomfort associated with the procedure | Very Low | Not specified |
| children with decayed primary molar teeth | preformed crown | non-restorative caries treatment | Gingival bleeding - long term (12 months) | Very Low | Not specified |
| children with decayed primary molar teeth | preformed crown | non-restorative caries treatment | Major failure (12 months) | Very Low | Not specified |
Previous Versions
CD005512.PUB2
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| Children with dental caries | Preformed metal crowns | Conventional restorations | Treatment success | No Evidence Yet | - |
CD005514
Current Version: CD005514.PUB2
Current Evidence Gaps 9 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| Adults with sleep bruxism | Occlusal splint | Palatal splint | Arousal index | No Evidence Yet | N/A |
| Adults with sleep bruxism | Occlusal splint | Palatal splint | Awakenings during sleep | No Evidence Yet | N/A |
| Adults with sleep bruxism | Occlusal splint | Palatal splint | Episodes with grinding noise | No Evidence Yet | N/A |
| Adults with sleep bruxism | Occlusal splint | Palatal splint | Total sleep time | No Evidence Yet | N/A |
| Adults with sleep bruxism | Occlusal splint | Palatal splint | Bruxism episodes per hour | No Evidence Yet | N/A |
| Adults with sleep bruxism | Occlusal splint | Palatal splint | Sleep efficiency | No Evidence Yet | N/A |
| Adults with TMD and bruxism | Occlusal splint | TENS | Clicks in TMJ (opening or closing) | No Evidence Yet | N/A |
| Adults with TMD and bruxism | Occlusal splint | TENS | Clicks in TMJ during opening/closing | No Evidence Yet | N/A |
| Children with bruxism | Occlusal splint | No treatment | Increase in wear facets size | No Evidence Yet | N/A |
CD005515
Current Version: CD005515.PUB3
| 1 older version
Current Evidence Gaps 6 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| Children with anterior open bite | FR-4 with lip-seal training | No treatment | Open bite correction | No Evidence Yet | N/A |
| Children with anterior open bite | FR-4 with lip-seal training | No treatment | Total anterior facial height change (mm) | No Evidence Yet | N/A |
| Children with anterior open bite | FR-4 with lip-seal training | No treatment | Upper incisor retrusion (degrees) | No Evidence Yet | N/A |
| Children with anterior open bite | Removable appliance with palatal crib + high-pull chincup | No treatment | Open bite correction | No Evidence Yet | N/A |
| Children with anterior open bite | Removable appliance with palatal crib + high-pull chincup | No treatment | Skeletal changes (angles SN.GoGN SN.PP NS.Gn) | No Evidence Yet | N/A |
| Children with anterior open bite | Repelling-magnet splints | Bite-blocks | Open bite correction | No Evidence Yet | N/A |
Previous Versions
CD005515.PUB2
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| Children with anterior open bite | FR-4 with lip-seal training | No treatment | Total anterior facial height change | No Evidence Yet | - |
| Children with anterior open bite | FR-4 with lip-seal training | No treatment | Total posterior facial height change | No Evidence Yet | - |
| Children with anterior open bite | FR-4 with lip-seal training | No treatment | Lower anterior facial height change | No Evidence Yet | - |
| Children with anterior open bite | FR-4 with lip-seal training | No treatment | Upper incisor retrusion (1/ANSPNS) | No Evidence Yet | - |
| Children with anterior open bite | FR-4 with lip-seal training | No treatment | Open bite correction | No Evidence Yet | - |
| Children with anterior open bite | Removable appliance with palatal crib + high-pull chincup | No treatment | Open bite correction | No Evidence Yet | - |
| Children with anterior open bite | Removable appliance with palatal crib + high-pull chincup | No treatment | Skeletal changes (SNA/SNB/angles) | No Evidence Yet | - |
| Children with anterior open bite | Repelling-magnet splints | Bite-blocks | Open bite correction | No Evidence Yet | - |
CD005516
Current Version: CD005516.PUB2
Current Evidence Gaps 5 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| Children and adults with fixed orthodontic brackets | Self etching primers (oneâstep etchant and primer system) | Conventional etchants (twoâstep etch and prime method using 37% phosphoric acid) | Bond failure rate (5 to 37 months) | Low | Not specified |
| Children and adults with fixed orthodontic brackets | Self etching primers (oneâstep etchant and primer system) | Conventional etchants (twoâstep etch and prime method using 37% phosphoric acid) | Cost of treatment | No Evidence Yet | N/A |
| Children and adults with fixed orthodontic brackets | Self etching primers (oneâstep etchant and primer system) | Conventional etchants (twoâstep etch and prime method using 37% phosphoric acid) | Damage to the teeth | No Evidence Yet | N/A |
| Children and adults with fixed orthodontic brackets | Self etching primers (oneâstep etchant and primer system) | Conventional etchants (twoâstep etch and prime method using 37% phosphoric acid) | Decay (decalcification) associated with or around the etching field | No Evidence Yet | N/A |
| Children and adults with fixed orthodontic brackets | Self etching primers (oneâstep etchant and primer system) | Conventional etchants (twoâstep etch and prime method using 37% phosphoric acid) | Participant satisfaction | No Evidence Yet | N/A |
CD005517
Current Version: CD005517.PUB3
| 1 older version
Current Evidence Gaps 13 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| patients needing retrograde filling in root canal therapy | Dentine-bonded resin composite | Glass ionomer cement | Adverse events | No Evidence Yet | N/A |
| patients needing retrograde filling in root canal therapy | Glass ionomer cement | Amalgam | Adverse events | No Evidence Yet | N/A |
| patients needing retrograde filling in root canal therapy | MTA | Super-EBA | Adverse events | No Evidence Yet | N/A |
| patients needing retrograde filling in root canal therapy | MTA | RRM | Adverse events | No Evidence Yet | N/A |
| patients needing retrograde filling in root canal therapy | MTA | IRM | Adverse events | No Evidence Yet | N/A |
| patients needing retrograde filling in root canal therapy | Super-EBA | IRM | Adverse events | No Evidence Yet | N/A |
| patients needing retrograde filling in root canal therapy | Dentine-bonded resin composite | Glass ionomer cement | Success rate â 1-year outcome PP analysis (root as unit of analysis) | Very Low | Not specified |
| patients needing retrograde filling in root canal therapy | Dentine-bonded resin composite | Glass ionomer cement | Success rate â 1-year outcome PP analysis (tooth as unit of analysis) | Very Low | Not specified |
| patients needing retrograde filling in root canal therapy | Glass ionomer cement | Amalgam | Success rate â 1-year outcome (tooth as unit of analysis) | Very Low | Not specified |
| patients needing retrograde filling in root canal therapy | MTA | RRM | Success rate â 1-year outcome (tooth as unit of analysis) | Very Low | Not specified |
| patients needing retrograde filling in root canal therapy | MTA | IRM | Success rate â 1-year outcome (tooth as unit of analysis) | Very Low | Not specified |
| patients needing retrograde filling in root canal therapy | MTA | Super-EBA | Success rate â 1-year outcome (tooth as unit of analysis) | Very Low | Not specified |
| patients needing retrograde filling in root canal therapy | Super-EBA | IRM | Success rate â 1-year outcome (tooth as unit of analysis) | Very Low | Not specified |
Previous Versions
CD005517.PUB2
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| patients needing retrograde filling in root canal therapy | MTA | IRM | Success rate - 1-year outcome (teeth as unit of analysis) | Low | - |
| patients needing retrograde filling in root canal therapy | Dentine-bonded resin composite | Glass ionomer cement | Success rate - 1-year outcome PP analysis (participants as unit of analysis) | Very Low | - |
| patients needing retrograde filling in root canal therapy | Dentine-bonded resin composite | Glass ionomer cement | Success rate - 1-year outcome PP analysis (root as unit of analysis) | Very Low | - |
| patients needing retrograde filling in root canal therapy | Glass ionomer cement | Amalgam | Success rate - 5-year outcome | Very Low | - |
| patients needing retrograde filling in root canal therapy | MTA | Super-EBA | Success rate - 1-year outcome (participants as unit of analysis) | Very Low | - |
| patients needing retrograde filling in root canal therapy | Super-EBA | IRM | Success rate - 1-year outcome (teeth as unit of analysis) | Very Low | - |
CD005519
Current Version: CD005519.PUB2
Current Evidence Gaps 5 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| Adults with halitosis | Tongue cleaner | Toothbrush | VSC reduction at 15-25 minutes | No Evidence Yet | N/A |
| Adults with halitosis | Tongue scraper | Toothbrush | VSC reduction | No Evidence Yet | N/A |
| Adults with halitosis | Tongue scraper | Toothbrush | VSC reduction at 15-25 minutes | No Evidence Yet | N/A |
| Adults with halitosis | Toothbrush | No intervention | VSC reduction | No Evidence Yet | N/A |
| Adults with halitosis | Toothbrush | No intervention | VSC reduction at 15-25 minutes | No Evidence Yet | N/A |
CD005520
Current Version: CD005520.PUB3
| 1 older version
Current Evidence Gaps 7 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| Children (age range 4 to 10 years old) | Oral appliance | No treatment | Daytime symptoms: Sleepiness | Very Low | Not specified |
| Children (age range 4 to 10 years old) | Oral appliance | No treatment | Daytime symptoms: Tiredness | Very Low | Not specified |
| Children (age range 4 to 10 years old) | Oral appliance | No treatment | Daytime symptoms: Irritability | Very Low | Not specified |
| Children (age range 4 to 10 years old) | Oral appliance | No treatment | Daytime symptoms: School problems | Very Low | Not specified |
| Children (age range 4 to 10 years old) | Oral appliance | No treatment | Daytime symptoms: Morning headache | Very Low | Not specified |
| Children (age range 4 to 10 years old) | Oral appliance | No treatment | Daytime symptoms: Oral breathing | Very Low | Not specified |
| Children (age range 4 to 10 years old) | Oral appliance | No treatment | Apnoeaâhypopnoea index (AHI) | Very Low | Not specified |
Previous Versions
CD005520.PUB2
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| Children 4-10 years with apnea index >1 and dysgnathia | Oral appliance | No treatment | Oral breathing | No Evidence Yet | - |
| Children 4-10 years with apnea index >1 and dysgnathia | Oral appliance | No treatment | Restless sleep | No Evidence Yet | - |
| Children 4-10 years with apnea index >1 and dysgnathia | Oral appliance | No treatment | Habitual snoring | No Evidence Yet | - |
| Children 4-10 years with apnea index >1 and dysgnathia | Oral appliance | No treatment | Nasal stuffiness | No Evidence Yet | - |
| Children 4-10 years with apnea index >1 and dysgnathia | Oral appliance | No treatment | Apnea-hypopnea index reduction | No Evidence Yet | - |
CD005620
Current Version: CD005620.PUB3
| 1 older version
Current Evidence Gaps 4 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| people with permanent or adult posterior teeth | composite | amalgam | Failure rate | Low | Not specified |
| people with permanent or adult posterior teeth | composite | amalgam | Fracture of restorations | Low | Not specified |
| people with permanent or adult posterior teeth | composite | amalgam | Secondary caries | Low | Not specified |
| people with permanent or adult posterior teeth | composite | amalgam | Harms | Very Low | Not specified |
Previous Versions
CD005620.PUB2
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| people with permanent or adult posterior teeth | composite | amalgam | Failure rate | Low | - |
| people with permanent or adult posterior teeth | composite | amalgam | Secondary caries | Low | - |
| people with permanent or adult posterior teeth | composite | amalgam | Fracture of restorations | Low | - |
| people with permanent or adult posterior teeth | composite | amalgam | Adverse events | No Evidence Yet | - |
CD005968
Current Version: CD005968.PUB3
| 1 older version
Current Evidence Gaps 10 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| Patients requiring single tooth implants | Autogenous bone graft | No augmentation | Implant failures and complications | No Evidence Yet | N/A |
| Patients requiring single tooth implants | Bio-Oss + barrier | Bio-Oss alone | Bone gain | No Evidence Yet | N/A |
| Patients requiring single tooth implants | Immediate-delayed implants | Delayed implants | Patient perception of treatment period | No Evidence Yet | N/A |
| Patients requiring single tooth implants | Immediate-delayed implants | Delayed implants | Complications at 5 years | No Evidence Yet | N/A |
| Patients requiring single tooth implants | Immediate-delayed implants | Delayed implants | Marginal mucosa level appropriateness | No Evidence Yet | N/A |
| Patients requiring single tooth implants | Immediate-delayed implants | Delayed implants | Patient satisfaction | No Evidence Yet | N/A |
| Patients requiring single tooth implants | Immediate implants | Delayed implants | Papilla height and marginal mucosa level | No Evidence Yet | N/A |
| Patients requiring single tooth implants | Immediate implants | Delayed implants | Implant failures | No Evidence Yet | N/A |
| Patients requiring single tooth implants | Immediate implants | Delayed implants | Prosthesis failures | No Evidence Yet | N/A |
| Patients requiring single tooth implants | Immediate implants | Immediate-delayed implants | Marginal mucosa level | No Evidence Yet | N/A |
Previous Versions
CD005968.PUB2
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| Adults needing single tooth replacement | Immediate-delayed implants | Delayed implants | Marginal mucosa level appropriateness | No Evidence Yet | - |
| Adults needing single tooth replacement | Immediate-delayed implants | Delayed implants | Patient satisfaction - Treatment period perception | No Evidence Yet | - |
| Adults needing single tooth replacement | Immediate-delayed implants | Delayed implants | Overall patient satisfaction | No Evidence Yet | - |
| Adults needing single tooth replacement | Immediate-delayed implants | Delayed implants | Papilla height | No Evidence Yet | - |
| Adults needing single tooth replacement | Immediate-delayed implants | Delayed implants | Implant failure | No Evidence Yet | - |
| Adults needing single tooth replacement | Immediate-delayed implants | Delayed implants | Prosthesis failure | No Evidence Yet | - |
| Adults needing single tooth replacement | Immediate implants | Delayed implants | Implant failure | No Evidence Yet | - |
| Adults needing single tooth replacement | Immediate implants | Delayed implants | Complications | No Evidence Yet | - |
| Adults needing single tooth replacement | Immediate implants | Delayed implants | Prosthesis failure | No Evidence Yet | - |
CD005969
Current Version: CD005969.PUB3
| 1 older version
Current Evidence Gaps 1 gap
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| Patients requiring endodontic surgery | Magnification devices | nan | nan | No Evidence Yet | N/A |
Previous Versions
CD005969.PUB2
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| Patients requiring endodontic treatment | Magnification devices | No magnification | Treatment outcomes | No Evidence Yet | - |
CD005970
Current Version: CD005970.PUB3
| 1 older version
Current Evidence Gaps 7 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| Adults with defective amalgam restorations in a molar or premolar tooth/teeth | Repair of defective amalgam restoration (with amalgam) | Replacement of defective amalgam restoration (with amalgam) | Perioperative or postoperative pain or discomfort | No Evidence Yet | N/A |
| Adults with defective amalgam restorations in a molar or premolar tooth/teeth | Repair of defective amalgam restoration (with amalgam) | Replacement of defective amalgam restoration (with amalgam) | Patient satisfaction as measured by patient satisfaction or aesthetic scales | No Evidence Yet | N/A |
| Adults with defective amalgam restorations in a molar or premolar tooth/teeth | Repair of defective amalgam restoration (with amalgam) | Replacement of defective amalgam restoration (with amalgam) | Adverse events | No Evidence Yet | N/A |
| Adults with defective amalgam restorations in a molar or premolar tooth/teeth | Repair of defective amalgam restoration (with amalgam) | Replacement of defective amalgam restoration (with amalgam) | Success or failure of restoration using a defined criteria | No Evidence Yet | N/A |
| Adults with defective amalgam restorations in a molar or premolar tooth/teeth | Repair of defective amalgam restoration (with amalgam) | Replacement of defective amalgam restoration (with amalgam) | Further restoration required | No Evidence Yet | N/A |
| Adults with defective amalgam restorations in a molar or premolar tooth/teeth | Repair of defective amalgam restoration (with amalgam) | Replacement of defective amalgam restoration (with amalgam) | Extraction of tooth (due to decay) | No Evidence Yet | N/A |
| Adults with defective amalgam restorations in a molar or premolar tooth/teeth | Repair of defective amalgam restoration (with amalgam) | Replacement of defective amalgam restoration (with amalgam) | Presence of clinical symptoms (pain, swelling, diagnosis of pulpitis, abscess formation) | No Evidence Yet | N/A |
Previous Versions
CD005970.PUB2
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| Patients requiring dental restoration repairs | Restoration repair materials | nan | nan | No Evidence Yet | - |
CD005971
Current Version: CD005971.PUB3
| 1 older version
Current Evidence Gaps 7 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| Adults with defective resin composite restorations in a molar or premolar tooth/teeth | Repair of defective resin composite restoration (with resin composite) | Replacement of defective resin composite restoration (with resin composite) | Presence of clinical symptoms (pain, swelling, diagnosis of pulpitis, abscess formation) | No Evidence Yet | N/A |
| Adults with defective resin composite restorations in a molar or premolar tooth/teeth | Repair of defective resin composite restoration (with resin composite) | Replacement of defective resin composite restoration (with resin composite) | Adverse events | No Evidence Yet | N/A |
| Adults with defective resin composite restorations in a molar or premolar tooth/teeth | Repair of defective resin composite restoration (with resin composite) | Replacement of defective resin composite restoration (with resin composite) | Patient satisfaction as measured by patient satisfaction or aesthetic scales | No Evidence Yet | N/A |
| Adults with defective resin composite restorations in a molar or premolar tooth/teeth | Repair of defective resin composite restoration (with resin composite) | Replacement of defective resin composite restoration (with resin composite) | Perioperative or postoperative pain or discomfort | No Evidence Yet | N/A |
| Adults with defective resin composite restorations in a molar or premolar tooth/teeth | Repair of defective resin composite restoration (with resin composite) | Replacement of defective resin composite restoration (with resin composite) | Success or failure of restoration, using a defined criteria | No Evidence Yet | N/A |
| Adults with defective resin composite restorations in a molar or premolar tooth/teeth | Repair of defective resin composite restoration (with resin composite) | Replacement of defective resin composite restoration (with resin composite) | Further restoration required | No Evidence Yet | N/A |
| Adults with defective resin composite restorations in a molar or premolar tooth/teeth | Repair of defective resin composite restoration (with resin composite) | Replacement of defective resin composite restoration (with resin composite) | Extraction of tooth (due to decay) | No Evidence Yet | N/A |
Previous Versions
CD005971.PUB2
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| Patients with dental restorations | Restoration repair | nan | nan | No Evidence Yet | - |
CD005972
Current Version: CD005972.PUB4
| 2 older versions
Current Evidence Gaps 1 gap
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| children with deep bite and retroclined upper front teeth | orthodontic treatment | extraction or no treatment | Dentoâocclusal results of treatment, measured with the PAR index | No Evidence Yet | N/A |
Previous Versions
CD005972.PUB3
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| nan | nan | nan | nan | No Evidence Yet | - |
CD005972.PUB2
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| nan | nan | nan | nan | No Evidence Yet | - |
CD006087
Current Version: CD006087.PUB3
| 1 older version
Current Evidence Gaps 10 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| Mandibular angle fracture patients | Combined transbuccal-intraoral | Intraoral alone | Infection at 3 months | No Evidence Yet | N/A |
| Mandibular angle fracture patients | Combined transbuccal-intraoral | Intraoral alone | Wound dehiscence at 3 months | No Evidence Yet | N/A |
| Mandibular angle fracture patients | Combined transbuccal-intraoral | Intraoral alone | Non-union | No Evidence Yet | N/A |
| Mandibular angle fracture patients | Combined transbuccal-intraoral | Intraoral alone | Plate removal | No Evidence Yet | N/A |
| Mandibular angle fracture patients | Single miniplate | Two miniplates | Post-operative infection | No Evidence Yet | N/A |
| Mandibular fracture patients | 3D miniplates | Conventional plates | Post-operative infection | No Evidence Yet | N/A |
| Mandibular fracture patients | 3D miniplates | Conventional miniplates | Post-operative MMF requirement | No Evidence Yet | N/A |
| Mandibular fracture patients | Resorbable plates | Titanium plates | Malocclusion | No Evidence Yet | N/A |
| Mandibular fracture patients | Resorbable plates | Titanium plates | Neurosensory disturbance at 1 month | No Evidence Yet | N/A |
| Mandibular fracture patients | Resorbable plates | Titanium plates | Mobility | No Evidence Yet | N/A |
Previous Versions
CD006087.PUB2
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| Edentulous patients with mandibular condyle fractures | Conservative or surgical interventions | nan | nan | No Evidence Yet | - |
CD006202
Current Version: CD006202.PUB2
Current Evidence Gaps 72 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| Adults undergoing bleaching | 16% CP + ACP gel in tray | 16% CP gel in tray | Tooth whitening - 6 months | Low | Not specified |
| Adults undergoing bleaching | 6.5% HP strips | 16% CP gel in tray | Tooth whitening - 21 days | Low | Not specified |
| Adults undergoing bleaching | 6% HP strips | Placebo | Tooth whitening - 2 weeks | Low | Not specified |
| Adults undergoing bleaching | 18% CP paint-on gel | Placebo | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | 6% HP gel | Placebo | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | 6% HP paint-on gel | Placebo | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | CP gel in tray | Placebo | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | CP gel in tray | HP gel in tray | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | CP gel in tray | CP gel in tray | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | CP paint-on gel | HP strips | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | CP paint-on gel | CP paint-on gel | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | HP mouthwash | Placebo | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | HP paint-on gel | CP paint-on gel | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | HP paint-on gel | HP strips | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | HP paint-on gel | HP paint-on gel | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | HP strips | HP gel in tray | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | HP strips | HP strips | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | HP strips | CP gel in tray | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | HP strips | Placebo | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | SHMP chewing gum | Placebo | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | SPC paint-on gel | CP paint-on gel | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | STPP chewing gum | Placebo | Adverse effects | No Evidence Yet | N/A |
| Adults undergoing bleaching | 10% CP gel (dark shade) | Placebo | Tooth whitening - 2 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 10% CP gel in tray | Placebo | Tooth whitening - 6 months | Very Low | Not specified |
| Adults undergoing bleaching | 10% CP gel in tray | 10% CP gel in tray | Tooth whitening - 2 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 10% CP gel (lighter shade) | Placebo | Tooth whitening - 2 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 10% CP gel (medium dark shade) | Placebo | Tooth whitening - 2 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 10% CP gel with desensitiser | Placebo | Tooth whitening - 2 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 10% CP + KN + NaF gel in tray | 10% CP gel in tray | Tooth whitening - 2 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 10% HP strips | Placebo | Tooth whitening - 15 days | Very Low | Not specified |
| Adults undergoing bleaching | 10% HP strips | Placebo | Tooth whitening - 8 days | Very Low | Not specified |
| Adults undergoing bleaching | 14% HP strips | 9.5% HP gel in tray | Tooth whitening - 22 days | Very Low | Not specified |
| Adults undergoing bleaching | 14% HP strips | Placebo | Tooth whitening - 3 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 14% HP strips | Placebo | Tooth whitening - 6 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 14% HP strips | 35% CP gel in tray | Tooth whitening - 30 days | Very Low | Not specified |
| Adults undergoing bleaching | 15% CP gel in tray | 10% CP gel in tray | Tooth whitening - 2 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 1.5% HP + 0.05% HF mouthwash | Placebo | Tooth whitening - 6 months | Very Low | Not specified |
| Adults undergoing bleaching | 16.40% CP paint-on gel | 18% CP paint-on gel | Tooth whitening - 2 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 16% CP gel in tray | 10% CP gel in tray | Tooth whitening - 2-year follow-up | Very Low | Not specified |
| Adults undergoing bleaching | 17% CP gel in tray | 10% CP gel in tray | Tooth whitening - 3 weeks (patient-reported) | Very Low | Not specified |
| Adults undergoing bleaching | 18% CP paint-on gel | 6% HP strips | Tooth whitening | Very Low | Not specified |
| Adults undergoing bleaching | 18% CP paint-on gel | Placebo | Tooth whitening - 3 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 18% CP paint-on gel 4x 1 week | 18% CP paint-on gel 2x 1 week | Tooth whitening - 1 week | Very Low | Not specified |
| Adults undergoing bleaching | 19% SPC paint-on gel | 18% CP paint-on gel | Tooth whitening - 14 days | Very Low | Not specified |
| Adults undergoing bleaching | 1% STPP chewing gum | Placebo | Tooth whitening - 6 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 4% SHMP chewing gum | Placebo | Tooth whitening - 12 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 5.3% HP strips | Placebo | Tooth whitening - 6 months | Very Low | Not specified |
| Adults undergoing bleaching | 5.3% HP strips | 5% HP gel in tray | Tooth whitening - 18 months | Very Low | Not specified |
| Adults undergoing bleaching | 5.3% HP strips | 5% HP gel in tray | Patient comfort | Very Low | Not specified |
| Adults undergoing bleaching | 5.6% SHMP chewing gum | Placebo | Tooth whitening - 3 days | Very Low | Not specified |
| Adults undergoing bleaching | 5.9% HP paint-on gel | 5.9% HP strips | Tooth whitening | Very Low | Not specified |
| Adults undergoing bleaching | 5.9% HP paint-on gel | 5.9% HP strips | Patient satisfaction | Very Low | Not specified |
| Adults undergoing bleaching | 5% CP gel in tray | 10% CP gel in tray | Tooth whitening - 2 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 5% CP gel in tray | Placebo | Tooth whitening - 2 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 6.5% HP strips | 15% CP gel in tray | Tooth whitening - 3 months | Very Low | Not specified |
| Adults undergoing bleaching | 6% HP gel | Placebo | Tooth whitening - 14 days | Very Low | Not specified |
| Adults undergoing bleaching | 6% HP gel in tray | 10% CP gel in tray | Tooth whitening - 2 weeks (darker shade) | Very Low | Not specified |
| Adults undergoing bleaching | 6% HP gel in tray | 10% CP gel in tray | Tooth whitening - 2 weeks (medium dark and lighter shade) | Very Low | Not specified |
| Adults undergoing bleaching | 6% HP paint-on gel | Placebo | Tooth whitening - 2 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 6% HP paint-on gel with KF | 6% HP paint-on gel | Tooth whitening | Very Low | Not specified |
| Adults undergoing bleaching | 6% HP strips | 5% CP + 5% KN gel in tray | Tooth whitening - 1 week | Very Low | Not specified |
| Adults undergoing bleaching | 6% HP strips | 10% CP gel in tray | Tooth whitening - 2 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 6% HP strips | 10% HP thin gel strips | Tooth whitening - 15 days | Very Low | Not specified |
| Adults undergoing bleaching | 6% HP strips | Placebo | Tooth whitening - 6 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 6% HP strips | 10% CP gel in tray | Tooth whitening - 6 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 7.5% HP gel in tray | 20% CP gel in tray | Tooth whitening - 12 days | Very Low | Not specified |
| Adults undergoing bleaching | 7.5% HP gel in tray | 10% CP gel in tray | Tooth whitening - 2 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 7.5% HP gel in tray | 20% CP gel in tray | Tooth whitening - 12 weeks | Very Low | Not specified |
| Adults undergoing bleaching | 7.5% SHMP chewing gum | Placebo | Tooth whitening - 2 days | Very Low | Not specified |
| Adults undergoing bleaching | 8.75% HP paint-on gel | 25% CP paint-on gel | Tooth whitening | Very Low | Not specified |
| Adults undergoing bleaching | 9.5% adhesion HP strips | 10% HP strips | Tooth whitening - 9 days | Very Low | Not specified |
| Adults undergoing bleaching | 9% HP gel in tray | 20% CP gel in tray | Tooth whitening - 2 weeks | Very Low | Not specified |
CD006203
Current Version: CD006203.PUB2
Current Evidence Gaps 1 gap
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| nan | nan | nan | nan | No Evidence Yet | N/A |
CD006204
Current Version: CD006204.PUB3
| 1 older version
Current Evidence Gaps 5 gaps
| Population | Intervention | Comparison | Outcome | Evidence Level | Downgrade Reason |
|---|---|---|---|---|---|
| Adults undergoing orthognathic surgery | Resorbable plates | Titanium plates | Adverse effects | Very Low | Not specified |
| Adults undergoing orthognathic surgery | Resorbable plates | Titanium plates | Postoperative pain during the immediate recovery period | Very Low | Not specified |
| Adults undergoing orthognathic surgery | Resorbable plates | Titanium plates | Patient satisfaction | Very Low | Not specified |
| Adults undergoing orthognathic surgery | Resorbable plates | Titanium plates | Postoperative chronic or lasting pain | Very Low | Not specified |
| Adults undergoing orthognathic surgery | Resorbable plates | Titanium plates | Need for retreatment or replacement of fixation due to failure of the fixation | Very Low | Not specified |
Previous Versions
CD006204.PUB2
| Population | Intervention | Comparison | Outcome | Evidence Level | Studies |
|---|---|---|---|---|---|
| Adults undergoing orthognathic surgery | Resorbable plates | Titanium plates | Plate infection rate | No Evidence Yet | - |
| Adults undergoing orthognathic surgery | Resorbable plates | Titanium plates | Patient satisfaction at 4-6 months | No Evidence Yet | - |
| Adults undergoing orthognathic surgery | Resorbable plates | Titanium plates | Wound discomfort at 4-6 months | No Evidence Yet | - |
| Adults undergoing orthognathic surgery | Resorbable plates | Titanium plates | Wound dehiscence | No Evidence Yet | - |
| Adults undergoing orthognathic surgery | Resorbable plates | Titanium plates | Plate exposure rate | No Evidence Yet | - |
Showing 81 to 100 of 214 review series
Summary Statistics
214
Review Series
3688
PICO Questions
Evidence Certainty
High
(%)
Moderate
(%)
Low
(%)
Very Low
(%)
No Evidence Yet
(%)
GRADE Downgrading Reasons
Risk of Bias
985
(85.8%)
Imprecision
895
(78.0%)
Inconsistency
253
(22.0%)
Indirectness
188
(16.4%)
Publication Bias
48
(4.2%)