Evidence Gaps Analysis

3688 outcomes from 214 review series
Clear
CD008072
Current Version: CD008072.PUB2
Current Evidence Gaps 10 gaps
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
People with dental caries ART using H-GIC Conventional treatment using H-GIC Restoration failure (primary dentition) at 12 to 24 months Low Not specified
People with dental caries ART using H-GIC Conventional treatment using H-GIC Pain Low Not specified
People with dental caries ART using composite Conventional treatment using composite Pain No Evidence Yet N/A
People with dental caries ART using composite Conventional treatment using composite Adverse events No Evidence Yet N/A
People with dental caries ART using H-GIC Conventional treatment using H-GIC Adverse events No Evidence Yet N/A
People with dental caries ART using RM-GIC Conventional treatment using RM-GIC Adverse events No Evidence Yet N/A
People with dental caries ART using RM-GIC Conventional treatment using RM-GIC Restoration failure (primary dentition) No Evidence Yet N/A
People with dental caries ART using RM-GIC Conventional treatment using RM-GIC Pain No Evidence Yet N/A
People with dental caries ART using composite Conventional treatment using composite Restoration failure (primary dentition) Very Low Not specified
People with dental caries ART using RM-GIC Conventional treatment using RM-GIC Restoration failure (permanent teeth) Very Low Not specified
CD008092
Current Version: CD008092.PUB2
Current Evidence Gaps 18 gaps
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
Oral ELP 0.025% Clobetasol 0.05% Clobetasol Pain reduction No Evidence Yet N/A
Oral ELP 0.025% Clobetasol microspheres Conventional formulation Pain reduction No Evidence Yet N/A
Oral ELP 0.05% Clobetasol 5% Mesalazine gel Pain reduction No Evidence Yet N/A
Oral ELP 0.1% Tacrolimus 0.05% Clobetasol Pain reduction No Evidence Yet N/A
Oral ELP 0.1% Triamcinolone Betamethasone pulse Clinical severity at 24 weeks No Evidence Yet N/A
Oral ELP 1.5% Ciclosporin 0.025% Clobetasol Pain improvement ≥50% No Evidence Yet N/A
Oral ELP 1.5% Ciclosporin gel 0.025% Clobetasol Clinical improvement No Evidence Yet N/A
Oral ELP 1% Pimecrolimus cream Placebo Clinical response (strong improvement) No Evidence Yet N/A
Oral ELP 1% Pimecrolimus cream Placebo Complete clearance No Evidence Yet N/A
Oral ELP 1% Pimecrolimus cream Placebo Clinical score No Evidence Yet N/A
Oral ELP 1% Pimecrolimus cream Placebo Pain when feeding No Evidence Yet N/A
Oral ELP 1% Pimecrolimus cream Placebo Basal pain No Evidence Yet N/A
Oral ELP 1% Pimecrolimus cream Placebo Pain reduction No Evidence Yet N/A
Oral ELP Aloe vera Placebo Clinical improvement ≥50% No Evidence Yet N/A
Oral ELP Aloe vera gel Placebo Pain improvement ≥50% No Evidence Yet N/A
Oral ELP Ciclosporin Vehicle Disease severity improvement No Evidence Yet N/A
Oral ELP Ciclosporin solution 0.1% Triamcinolone acetonide Pain reduction No Evidence Yet N/A
Oral ELP TGT THT Clinical response (Grade I lesions) No Evidence Yet N/A
CD008236
Current Version: CD008236.PUB3 | 1 older version
Current Evidence Gaps 3 gaps
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
Orthodontic patients with first permanent molars Bonded molar tubes Molar bands First time failure (tooth level) No Evidence Yet N/A
Orthodontic patients with first permanent molars Bonded molar tubes Molar bands Decalcification No Evidence Yet N/A
Orthodontic patients with first permanent molars Bonded molar tubes Molar bands First time failure (participant level) No Evidence Yet N/A
Previous Versions
CD008236.PUB2
Population Intervention Comparison Outcome Evidence Level Studies
Orthodontic patients with first permanent molars Bonded molar tubes Molar bands Decalcification No Evidence Yet -
Orthodontic patients with first permanent molars Bonded molar tubes Molar bands First time failure (patient level) No Evidence Yet -
Orthodontic patients with first permanent molars Bonded molar tubes Molar bands First time failure (tooth level) No Evidence Yet -
CD008367
Current Version: CD008367.PUB4 | 2 older versions
Current Evidence Gaps 8 gaps
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
critically ill adults and children receiving mechanical ventilation chlorhexidine (mouthrinse or gel) placebo or usual care Duration of ICU stay Low Not specified
critically ill adults receiving mechanical ventilation toothbrushing (± antiseptics) no toothbrushing (± antiseptics) Mortality Low Not specified
critically ill adults receiving mechanical ventilation toothbrushing (± antiseptics) no toothbrushing (± antiseptics) Incidence of VAP Low Not specified
critically ill adults receiving mechanical ventilation toothbrushing (± antiseptics) no toothbrushing (± antiseptics) Duration of ventilation Low Not specified
critically ill adults and children receiving mechanical ventilation chlorhexidine (mouthrinse or gel) placebo or usual care Incidence of VAP Moderate Not specified
critically ill adults and children receiving mechanical ventilation chlorhexidine (mouthrinse or gel) placebo or usual care Mortality Moderate Not specified
critically ill adults and children receiving mechanical ventilation chlorhexidine (mouthrinse or gel) placebo or usual care Duration of ventilation Very Low Not specified
critically ill adults and children receiving mechanical ventilation chlorhexidine (mouthrinse or gel) placebo or usual care Adverse effects Very Low Not specified
critically ill adults receiving mechanical ventilation toothbrushing (± antiseptics) no toothbrushing (± antiseptics) Adverse effects Very Low Not specified
critically ill adults receiving mechanical ventilation toothbrushing (± antiseptics) no toothbrushing (± antiseptics) Duration of ICU stay Very Low Not specified
Previous Versions
CD008367.PUB3
Population Intervention Comparison Outcome Evidence Level Studies
critically ill adults and children receiving mechanical ventilation chlorhexidine (mouthrinse or gel) placebo or usual care Ventilator-associated pneumonia High -
critically ill adults and children receiving mechanical ventilation chlorhexidine (mouthrinse or gel) placebo or usual care Duration of ventilation Low -
critically ill patients receiving mechanical ventilation toothbrushing (± chlorhexidine) no toothbrushing (± chlorhexidine) Duration of ventilation Low -
critically ill patients receiving mechanical ventilation toothbrushing (± chlorhexidine) no toothbrushing (± chlorhexidine) Mortality Low -
critically ill adults and children receiving mechanical ventilation chlorhexidine (mouthrinse or gel) placebo or usual care Duration of ICU stay Moderate -
critically ill adults and children receiving mechanical ventilation chlorhexidine (mouthrinse or gel) placebo or usual care Mortality Moderate -
critically ill adults and children receiving mechanical ventilation chlorhexidine (mouthrinse or gel) placebo or usual care Adverse effects Very Low -
critically ill patients receiving mechanical ventilation toothbrushing (± chlorhexidine) no toothbrushing (± chlorhexidine) Duration of ICU stay Very Low -
critically ill patients receiving mechanical ventilation toothbrushing (± chlorhexidine) no toothbrushing (± chlorhexidine) Incidence of VAP Very Low -
critically ill patients receiving mechanical ventilation toothbrushing (± chlorhexidine) no toothbrushing (± chlorhexidine) Adverse effects Very Low -
CD008367.PUB2
Population Intervention Comparison Outcome Evidence Level Studies
Critically ill patients to prevent ventilator-associated pneumonia Toothbrushing (± chlorhexidine) No toothbrushing (± chlorhexidine) Incidence of VAP Low -
Critically ill patients receiving mechanical ventilation Chlorhexidine (mouthrinse or gel) Placebo or usual care VAP Moderate -
Critically ill patients receiving mechanical ventilation Chlorhexidine (mouthrinse or gel) Placebo or usual care Duration of ICU stay Moderate -
Critically ill patients receiving mechanical ventilation Chlorhexidine (mouthrinse or gel) Placebo or usual care Duration of ventilation Moderate -
Critically ill patients receiving mechanical ventilation Chlorhexidine (mouthrinse or gel) Placebo or usual care Mortality Moderate -
Critically ill patients to prevent ventilator-associated pneumonia Toothbrushing (± chlorhexidine) No toothbrushing (± chlorhexidine) Duration of ICU stay Moderate -
Critically ill patients to prevent ventilator-associated pneumonia Toothbrushing (± chlorhexidine) No toothbrushing (± chlorhexidine) Duration of ventilation Moderate -
Critically ill patients to prevent ventilator-associated pneumonia Toothbrushing (± chlorhexidine) No toothbrushing (± chlorhexidine) Mortality Moderate -
CD008375
Current Version: CD008375.PUB2
Current Evidence Gaps 9 gaps
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
children and adolescents undergoing orthodontic treatment intraoral appliance headgear Movement of upper incisor teeth (mm) Low Not specified
children and adolescents undergoing orthodontic treatment intraoral appliance headgear Change in overjet (mm) Low Not specified
children and adolescents undergoing orthodontic treatment orthodontic appliance untreated control Movement of upper incisor teeth (mm) Low Not specified
children and adolescents undergoing orthodontic treatment orthodontic appliance untreated control Change in overjet (mm) Low Not specified
children and adolescents undergoing orthodontic treatment orthodontic appliance untreated control Movement of upper first molars (mm) Low Not specified
children and adolescents undergoing orthodontic treatment intraoral appliance headgear Movement of upper first molars (mm) Very Low Not specified
children and adolescents undergoing orthodontic treatment intraoral appliance other intraoral appliance Change in overjet (mm) Very Low Not specified
children and adolescents undergoing orthodontic treatment intraoral appliance other intraoral appliance Movement of upper incisor teeth (mm) Very Low Not specified
children and adolescents undergoing orthodontic treatment intraoral appliance other intraoral appliance Movement of upper first molars (mm) Very Low Not specified
CD008392
Current Version: CD008392.PUB3 | 1 older version
Current Evidence Gaps 2 gaps
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
children and adolescents having dental treatment ibuprofen placebo Postoperative pain (continuous measure: self report using visual analogue scale) Low Not specified
children and adolescents having dental treatment paracetamol placebo Postoperative pain (dichotomous measure: parent report of presence of pain‐related behaviours) Low Not specified
Previous Versions
CD008392.PUB2
Population Intervention Comparison Outcome Evidence Level Studies
Children and adolescents having dental treatment Ibuprofen Placebo Severity of postoperative pain Moderate -
Children and adolescents having dental treatment Paracetamol Placebo Presence of postoperative pain related behaviour Moderate -
CD008397
Current Version: CD008397.PUB2 | 1 older version
Current Evidence Gaps 3 gaps
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
patients with replacing missing teeth Long implants with sinus lift Short implants Complications Low Not specified
patients with replacing missing teeth Long implants with sinus lift Short implants Implant failures Moderate Not specified
patients with replacing missing teeth Long implants with sinus lift Short implants Prosthesis failures Moderate Not specified
patients with insufficient bone below maxillary sinus sinus lift procedure sinus lift procedure Prosthesis failures No Evidence Yet N/A
patients with insufficient bone below maxillary sinus sinus lift procedure sinus lift procedure Implant failures No Evidence Yet N/A
Previous Versions
CD008397
Population Intervention Comparison Outcome Evidence Level Studies
patients with insufficient bone below maxillary sinus PRP no PRP Implant failure (at 0 to 2 years) Low -
CD008455
Current Version: CD008455.PUB2
Current Evidence Gaps 3 gaps
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
people with bisphosphonate‐related osteonecrosis of the jaw (BRONJ) hyperbaric oxygen therapy in addition to surgery, antibiotics and oral rinse surgery, antibiotics and oral rinse Adverse effects No Evidence Yet N/A
people with bisphosphonate‐related osteonecrosis of the jaw (BRONJ) hyperbaric oxygen therapy in addition to surgery, antibiotics and oral rinse surgery, antibiotics and oral rinse Healing of osteonecrosis (dichotomous outcome ('healed' vs. 'improved', 'unchanged' and 'worse') measured at 3 months) Very Low Not specified
people with bisphosphonate‐related osteonecrosis of the jaw (BRONJ) hyperbaric oxygen therapy in addition to surgery, antibiotics and oral rinse surgery, antibiotics and oral rinse Improvement in osteonecrosis (dichotomous outcome ('healed' and 'improved' vs. 'unchanged' and 'worse') measured at 3 months) Very Low Not specified
CD008456
Current Version: CD008456.PUB2
Current Evidence Gaps 14 gaps
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
Burning mouth syndrome CBT Attention placebo Pain post-treatment No Evidence Yet N/A
Burning mouth syndrome CBT Attention placebo Pain at 6 months No Evidence Yet N/A
TMD patients CBT Usual care Depression No Evidence Yet N/A
TMD patients CBT Usual care Long-term pain No Evidence Yet N/A
TMD patients CBT Usual care Activity interference No Evidence Yet N/A
TMD patients CBT/biofeedback Usual care Depression No Evidence Yet N/A
TMD patients CBT/biofeedback combination Usual care Short-term pain No Evidence Yet N/A
TMD patients CBT/biofeedback combination Usual care Long-term pain No Evidence Yet N/A
TMD patients Habit reversal Waiting list control Pain post-treatment No Evidence Yet N/A
TMD patients Habit reversal Waiting list control Life interference No Evidence Yet N/A
TMD patients Hypnosis Relaxation Depression No Evidence Yet N/A
TMD patients Hypnosis Relaxation Pain intensity No Evidence Yet N/A
TMD patients Psychosocial interventions Usual care Long-term pain No Evidence Yet N/A
TMD patients Psychosocial interventions Usual care Depression No Evidence Yet N/A
CD008457
Current Version: CD008457.PUB2
Current Evidence Gaps 7 gaps
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
children and adolescents chlorhexidine gel no treatment Adverse events (24-months follow-up) No Evidence Yet N/A
children and adolescents chlorhexidine varnish placebo Caries in the primary teeth (24-months follow-up) No Evidence Yet N/A
children and adolescents chlorhexidine varnish placebo Adverse events No Evidence Yet N/A
children and adolescents chlorhexidine gel no treatment Mutans streptococci prevalence (24-months follow-up) Very Low Not specified
children and adolescents chlorhexidine gel no treatment Presence of new caries in the primary teeth (24-months follow-up) Very Low Not specified
children and adolescents chlorhexidine varnish placebo Caries in permanent dentition (DMFS) (30 to 36 months) Very Low Not specified
children and adolescents chlorhexidine varnish placebo Elevated mutans streptococci levels ≥4 with caries screen (6 to 36 months) Very Low Not specified
CD008464
Current Version: CD008464.PUB3 | 1 older version
Current Evidence Gaps 1 gap
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
nan nan nan nan No Evidence Yet N/A
Previous Versions
CD008464.PUB2
Population Intervention Comparison Outcome Evidence Level Studies
nan nan nan nan No Evidence Yet -
CD008676
Current Version: CD008676.PUB2
Current Evidence Gaps 1 gap
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
adults and children with gingivitis chlorhexidine mouthrinse placebo/control mouthrinse or no mouthrinse Gingival Index 4 to 6 weeks High None
adults and children with gingivitis chlorhexidine mouthrinse placebo/control mouthrinse or no mouthrinse Plaque 4 to 6 weeks High None
adults and children with gingivitis chlorhexidine mouthrinse placebo/control mouthrinse or no mouthrinse Tooth staining 4 to 6 weeks Moderate Not specified
adults and children with gingivitis chlorhexidine mouthrinse placebo/control mouthrinse or no mouthrinse Other adverse effects No Evidence Yet N/A
CD008694
Current Version: CD008694.PUB2
Current Evidence Gaps 6 gaps
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
children with pacifier or digit sucking habits orthodontic appliances (palatal arch/palatal crib) no treatment Sucking cessation (short term) Low Not specified
children with pacifier or digit sucking habits psychological interventions no treatment Sucking cessation (short term) Low Not specified
children with pacifier or digit sucking habits orthodontic appliances (palatal arch/palatal crib) no treatment Adverse events No Evidence Yet N/A
children with pacifier or digit sucking habits psychological interventions no treatment Occlusion No Evidence Yet N/A
children with pacifier or digit sucking habits psychological interventions no treatment Adverse events No Evidence Yet N/A
children with pacifier or digit sucking habits orthodontic appliances (palatal arch/palatal crib) no treatment Occlusion (changes in overbite) Very Low Not specified
CD008734
Current Version: CD008734.PUB2
Current Evidence Gaps 1 gap
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
Patients with relapse of lower front teeth Interventions to correct relapse nan nan No Evidence Yet N/A
CD008802
Current Version: CD008802.PUB3 | 1 older version
Current Evidence Gaps 18 gaps
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
People with serious mental illness Monitoring No monitoring Leaving the study early Moderate Not specified
People with serious mental illness Motivational interview plus oral health education Oral health education Leaving the study early Moderate Not specified
People with serious mental illness Oral health education Standard care Leaving the study early Moderate Not specified
People with serious mental illness Monitoring No monitoring Adverse events: Clinically important specific adverse events No Evidence Yet N/A
People with serious mental illness Monitoring No monitoring Service use: Emergency medical/dental treatment No Evidence Yet N/A
People with serious mental illness Monitoring No monitoring Oral health: Not having seen a dentist in the past year No Evidence Yet N/A
People with serious mental illness Monitoring No monitoring Dental state: No clinically important change in plaque index No Evidence Yet N/A
People with serious mental illness Monitoring No monitoring Oral health: Not brushing teeth twice a day No Evidence Yet N/A
People with serious mental illness Monitoring No monitoring Quality of life: Chronic pain No Evidence Yet N/A
People with serious mental illness Motivational interview plus oral health education Oral health education Quality of life: Chronic pain No Evidence Yet N/A
People with serious mental illness Motivational interview plus oral health education Oral health education Oral health: Not having seen a dentist in the past year No Evidence Yet N/A
People with serious mental illness Motivational interview plus oral health education Oral health education Oral health: Not brushing teeth twice a day No Evidence Yet N/A
People with serious mental illness Motivational interview plus oral health education Oral health education Adverse events: Clinically important specific adverse events No Evidence Yet N/A
People with serious mental illness Motivational interview plus oral health education Oral health education Service use: Emergency medical/dental treatment No Evidence Yet N/A
People with serious mental illness Oral health education Standard care Oral health: Not brushing teeth twice a day No Evidence Yet N/A
People with serious mental illness Oral health education Standard care Quality of life: Chronic pain No Evidence Yet N/A
People with serious mental illness Oral health education Standard care Adverse events: Clinically important specific adverse events No Evidence Yet N/A
People with serious mental illness Oral health education Standard care Service use: Emergency medical/dental treatment No Evidence Yet N/A
People with serious mental illness Oral health education Standard care Oral health: Not having seen a dentist in the past year No Evidence Yet N/A
People with serious mental illness Motivational interview plus oral health education Oral health education Dental state: No clinically important change in plaque index Very Low Not specified
People with serious mental illness Oral health education Standard care Dental state: No clinically important change in plaque index Very Low Not specified
Previous Versions
CD008802.PUB2
Population Intervention Comparison Outcome Evidence Level Studies
People with serious mental illness Oral health advice Standard care nan No Evidence Yet -
CD008829
Current Version: CD008829.PUB2
Current Evidence Gaps 7 gaps
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
everyday self-care flossing plus toothbrushing toothbrushing alone Interproximal caries No Evidence Yet N/A
everyday self-care flossing plus toothbrushing toothbrushing alone Harms and adverse effects No Evidence Yet N/A
everyday self-care flossing plus toothbrushing toothbrushing alone Quality of life No Evidence Yet N/A
everyday self-care flossing plus toothbrushing toothbrushing alone Clinical attachment loss No Evidence Yet N/A
everyday self-care flossing plus toothbrushing toothbrushing alone Calculus No Evidence Yet N/A
everyday self-care flossing plus toothbrushing toothbrushing alone Gingivitis Very Low Not specified
everyday self-care flossing plus toothbrushing toothbrushing alone Plaque Very Low Not specified
CD008857
Current Version: CD008857.PUB2
Current Evidence Gaps 1 gap
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
Patients requiring radiotherapy Extraction of teeth Leaving teeth in place nan No Evidence Yet N/A
CD008934
Current Version: CD008934.PUB2
Current Evidence Gaps 11 gaps
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
Dry mouth patients Chewing gum/lozenge Saliva spray Unstimulated whole saliva No Evidence Yet N/A
Elderly patients OGT spray Saliveeze spray Oral dryness No Evidence Yet N/A
Hemodialysis patients Chewing gum Xialine spray Mouth dryness (VAS) No Evidence Yet N/A
Hospice patients with terminal cancer Mucin spray Placebo spray Dry mouth improvement No Evidence Yet N/A
Patients with Sjogren's syndrome CMC mouthwash Glycerin mouthwash Excellent benefit No Evidence Yet N/A
Patients with Sjogren's syndrome Mucin lozenge Placebo lozenge Dry mouth (VAS) No Evidence Yet N/A
Radiotherapy patients Biotene system Control (CMC) Dry mouth (VAS) No Evidence Yet N/A
Radiotherapy patients Bioxtra system Biotene system Dry mouth No Evidence Yet N/A
Xerostomia patients Intraoral device with Biotene Manual Biotene gel Xerostomia Inventory No Evidence Yet N/A
Xerostomia patients Mucin spray Placebo spray Dry mouth (VAS) No Evidence Yet N/A
Xerostomia patients Reservoir biteguard Control biteguard Xerostomia Inventory No Evidence Yet N/A
CD008948
Current Version: CD008948.PUB2
Current Evidence Gaps 9 gaps
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
Root canal patients NaOCl 1% + Chlorhexidine 2% NaOCl 1% + Saline Positive bacterial growth No Evidence Yet N/A
Root canal patients NaOCl 2.5% Chlorhexidine 2% gel Positive bacterial growth No Evidence Yet N/A
Root canal patients NaOCl 5% NaOCl 5% + proteolytic enzyme Moderate to severe pain day 1 No Evidence Yet N/A
Root canal patients NaOCl 5% NaOCl 5% + proteolytic enzyme Swelling at day 1 No Evidence Yet N/A
Root canal patients NaOCl 5% NaOCl 1% Positive bacterial growth No Evidence Yet N/A
Root canal patients NaOCl 5.25% Chlorhexidine 2% Positive bacterial growth No Evidence Yet N/A
Root canal patients NaOCl 5.25% NaOCl 5.25% + H2O2 Moderate to severe pain No Evidence Yet N/A
Root canal patients Saline NaOCl 5.25% + H2O2 Moderate to severe pain No Evidence Yet N/A
Root canal patients Saline NaOCl 5.25% Moderate to severe pain No Evidence Yet N/A
CD009109
Current Version: CD009109.PUB3 | 1 older version
Current Evidence Gaps 3 gaps
Population Intervention Comparison Outcome Evidence Level Downgrade Reason
people with a permanent tooth that has undergone endodontic treatment composite filling with post covered with fullâcoverage metalâceramic crown (and oral hygiene instruction) composite filling with post (and oral hygiene instruction) Catastrophic failure of restoration Very Low Not specified
people with a permanent tooth that has undergone endodontic treatment composite filling with post covered with fullâcoverage metalâceramic crown (and oral hygiene instruction) composite filling with post (and oral hygiene instruction) Nonâcatastrophic failure of post Very Low Not specified
people with a permanent tooth that has undergone endodontic treatment composite filling with post covered with fullâcoverage metalâceramic crown (and oral hygiene instruction) composite filling with post (and oral hygiene instruction) Nonâcatastrophic failure of the restoration Very Low Not specified
Previous Versions
CD009109.PUB2
Population Intervention Comparison Outcome Evidence Level Studies
Adults with premolar teeth requiring endodontic treatment Composite + crown Composite only Post failure at 3 years No Evidence Yet -
Adults with premolar teeth requiring endodontic treatment Composite + crown Composite only Restoration failure at 3 years No Evidence Yet -
Showing 141 to 160 of 214 review series
Summary Statistics
214
Review Series
3688
PICO Questions
Evidence Certainty
High
(%)
Moderate
(%)
Low
(%)
Very Low
(%)
No Evidence Yet
(%)
GRADE Downgrading Reasons
Risk of Bias
985 (85.8%)
Imprecision
895 (78.0%)
Inconsistency
253 (22.0%)
Indirectness
188 (16.4%)
Publication Bias
48 (4.2%)